The Institute and the Comprehensive Biomedical Research Centre (CBRC)

  • University College NHS Foundation Trust and University College London


It is only fitting to acknowledge here the important contribution the CBRC has made to the further development of the Institute. Perhaps the single most important contribution was the support given to the funding of our Radiochemistry facility, now housed within UCL Chemistry. This is described in the relevant section of this book. Further support was given by the CBRC in its first quinquennial program. We outline below the last 2 years of the outcome of our CBRC program, as part of the Imaging Theme which our staff led in the first 5 years of the CBRC.


Myocardial Perfusion Imaging Interstitial Lung Disease Partial Volume Correction Primary Progressive Aphasia Patient Journey 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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21 Peer Reviewed Publications (2009–2010) acknowledging CBRC

  1. Menezes LJ, Kayani I, Bomanji J, Hutton BF, Ell PJ, Groves AM. What is the Natural History of 18F-FDG Uptake in Arterial Atheroma on PET/CT. Atherosclerosis. 2010 Jan 22. [Epub ahead of print] Pub Med PMID: 20202634.Google Scholar
  2. Taylor SA, Bomanlji JB, Mezpanzure, L, Robinson C, Groves AM, Dickson JC, Greenhalgh, R Cattinin G, Obichere A, Bloom S, Ell PJ, Halligan S. Non laxative positron emission tomography CT colonography: Feasibility, performance and acceptability in patients at higher risk of colonic neoplasia. J Nucl Med. 2010 Jun; 51(6):854–61. Epub 2010 May 19. Pub Med PMID: 20484420.PubMedCrossRefGoogle Scholar
  3. Kotze CW, Yusuf SW, Menezes LJ, Hutton BF, Ell PJ, Groves AM. Vascular Imaging with FDG PET/CT: optimal FDG circulation time. J Nucl Med. 2009 Aug 18. [Epub ahead of print] Pub Med PMID: 19690039.Google Scholar
  4. Kayani I, Conry BG, Groves AM, Caplan D, Win T, Bomanji J. A comparison of 68Ga-DOTATATE and 18F-FDG PET/CT in pulmonary neuroendocrine tumors. J Nucl Med. 2009 Dec; 50(12):1927–32. Epub 2009 Nov 12. Pub Med PMID: 19910422.PubMedCrossRefGoogle Scholar
  5. Groves AM, Speechly-Dick ME, Kayani I, Pugliese F, Habib S, Menezes L, Endozo R, Pruvlovich E, McEwan J, Ell PJ. First experience cardiac PET 64-detector/CT angiography with invasive angiography validation. Eur J Nucl Med Mol Imaging. 2009 Dec; 36(12):2027–33. Epub 2009 Jul 18. Pub Med PMID: 19618180.PubMedCrossRefGoogle Scholar
  6. Menezes LJ, Groves AM, Kayani I, Dickson JC, Endozoz R, Bomanji J, Hutton B, Ell P. Assessment of LV function at rest using Rb myocardial perfusion PET; Comparison of 4 different software algorithms with simultaneous 64 detector coronary CT. Nucl Med Commun. 2009 Dec; 30(12):918–25. PubMed PMID: 19884868.PubMedCrossRefGoogle Scholar
  7. Vijayanathan S, Butt S, Gopinath G, Groves AM. Advantages and limitations of imaging the musculoskeletal system by conventional radiological, radionuclide and hybrid modalities. Semin Nucl Med. 2009 Nov; 39(6):357–68. Review. PubMed PMID: 19801216.PubMedCrossRefGoogle Scholar
  8. Kotze CW, Menezes, L, Endozo R, Groves AM, Ell, PJ Yusuf SW. Increased metabolic activity in abdominal aortic aneurysm detected by 18F- fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT). Eur J Vasc Endovasc Surg. 2009 Jul; 38(1):93–9. Epub 2009 Feb 12. PubMed PMID: 19217326.PubMedCrossRefGoogle Scholar
  9. Groves AM, Win T, Screaton NJ, Berovic M, Endozo R, Booth H, Dickson JC, Ell PJ. Idiopathic Pulmonary Fibrosis and Diffuse Parenchymal Lung Disease: Implications from Initial Experience with 18F-FDG-PET/CT. J Nucl Med. 2009 Apr; 50(4):538–45. Epub 2009 Mar 16. PubMed PMID: 19289428.PubMedCrossRefGoogle Scholar
  10. Groves AM, Wishart GC, Shastry M, Moyle P, Iddles S, Britton P, Gaskarth M, Warren RM, Ell PJ, Miles KA. Metabolic-Flow Relationships in Primary Breast Cancer: Feasibility with Combined PET/ Dynamic Contrast Enhanced CT. Eur J Nucl Med Mol Imaging. 2009 Mar; 36(3):416–21. Epub 2008 Sep 26.PMID: 18818917.PubMedCrossRefGoogle Scholar
  11. McQuaid S, Lambrou T, Cunningham VJ, Bettinardi V, Gilardi MC, Hutton BF. The application of a statistical shape model to diaphragm tracking in respiratory gated PET images. European Journal of Nuclear Medicine and Molecular Imaging 2009; 36:416–421 Proc IEEE 2009; 97: 2039–2052. PubMed PMID:CrossRefGoogle Scholar
  12. Patton JA, Townsend DW, Hutton BF. Hybrid Imaging Technology: from dreams andVision to clinical devices. Semin Nucl Med. 2009 Jul; 39(4):247–63. Review. PubMed PMID: 19497402.PubMedCrossRefGoogle Scholar
  13. Mahmood S, Erlandsson K, Hutton BF. Design of a novel slit-slat collimator system for SPECT imaging of the human brain. Phys Med Biol. 2009 Jun 7; 54(11):3433–49. Epub 2009 May 13. PubMed PMID: 19436098.PubMedCrossRefGoogle Scholar
  14. Erlandsson K, Kacperski K, van Gramberg D, Hutton BF. Performance Evaluation of D-SPECT: a novel SPECT system designed for nuclear cardiology. Phys Med Biol. 2009 May 7; 54(9):2635–49. Epub 2009 Apr 8. PubMed PMID: 19351981.PubMedCrossRefGoogle Scholar
  15. Nunez M, Prakash V, Vila R, Mut F, Alonso O, Hutton BF. Attenuation correctionfor lung SPECT: evidence of need and validation of an attenuation map derived fromthe emission data. Eur J Nucl Med Mol Imaging. 2009 Jul; 36(7):1076–89. Epub 2009 Feb 24. PubMed PMID: 19238381.PubMedCrossRefGoogle Scholar
  16. Gambhir SS, Berman DS, Ziffer J, Nagler M, Dalia Dickman D, Rousso B, Sandler M. Patton J, Hutton B, Dichterman E, Ziv O, Melman H, Zilberstein Y, BenHaim S and Ben Haim S. A Novel High Sensitivity Rapid Acquisition Single PhotonMolecular Imaging Camera. J Nucl Med. 2009 Apr; 50(4):635–43. PubMed PMID: 19339672.PubMedCrossRefGoogle Scholar
  17. Ben-Haim SS, Kacperski K, Hain S, van Gramberg D, Hutton B, Erlandsson K, Sharir T, Roth N, Waddington WA, Berman DS and Ell PJ. Simultaneous dual-radionuclide myocardial perfusion imaging with a solid-state dedicated cardiac camera. Eur J Nucl Med Mol Imaging. 2010 Apr 11. PubMed PMID: 20383705.Google Scholar
  18. Menezes LJ, Kotze CW, Hutton BF, Endozo R, Dickson JC, Cullum I, Yusuf SW, Ell PJ, Groves AM. Vascular inflammation imaging with 18F-DFG PET/CT:when to image? J Nucl Med. 2009 Jun; 50(6):854–7. Epub 2009 May 14. PubMed PMID: 19443587.PubMedCrossRefGoogle Scholar
  19. Erlandsson K, Hutton BF. Partial volume correction in SPECT using anatomicalinformation and iterative FBP. Proc 10th International Meeting on Fully Three-DimensionalReconstruction in Radiology and Nuclear Medicine. 2009; pp 287–290. PubMed PMID:Google Scholar
  20. Torres Martin de Rosales R, Arstad E, Blower PJ. Nuclear Imaging of Molecular Processes in Cancer. Target Oncol. 2009 Sep; 4(3):183–97. Epub 2009 Sep 25. Review. PubMed PMID: 19779864.PubMedCrossRefGoogle Scholar
  21. Dickson JC, Tossici-Bolt L, Sera T, Erlandssson K, Varrone A, Tatsch K and Hutton B. The impact of reconstruction method on the quantification of DaTScan images. Eur J Nucl Med Mol Imaging. 2010 Jan; 37(1):23–35. Epub. PubMed PMID: 19618181.PubMedCrossRefGoogle Scholar

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© Springer-Verlag Berlin Heidelberg 2012

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  • University College NHS Foundation Trust and University College London

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