With single photon emission tomography being at the time the only practical tomographic imaging technology for radiolabeled probes, Costa and staff at the Institute published very early on an important study, characterizing in vivo an I-123 labelled neuroreceptor for the D2/D3 dopaminergic system – 3-iodo-6- methoxybenzamide – IBZM (European J Nuclear Medicine 1990). We show an IBZM study in a normal and a medicated patient, over a period of time, and the different degrees of receptor blockade in the striatum.
KeywordsReceptor Blockade Single Photon Emission Tomography Coronary Bypass Surgery Focal Epilepsy Brain Blood Flow
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