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Epidemiology of Diabetes and Obesity in Pregnancy

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Abstract

In the general population, increases in type 2 diabetes and obesity are apparent in many countries. In some societies, particularly the USA, rises have been very marked. Incidence of type 1 diabetes in childhood has also been noted to be increasing, albeit less dramatically. These secular trends have clear and important implications for those caring for women during pregnancy as the numbers of women with diabetes present before pregnancy will increase. Women with type 1 diabetes will likely have longer duration of disease by the time they fall pregnant. Type 2 diabetes, which in many countries was a relatively uncommon condition in pregnancy, is rapidly becoming commoner than type 1 diabetes as co-morbidity of pregnancy. Increases in obesity in the population will also increase the likelihood of gestational diabetes (diabetes with first onset or recognition in pregnancy). In this chapter, I will review secular increases in diabetes and obesity and how these increases have been translated into changes in the pregnant population.

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References

  • Boulot P, Chabbert-Buffet N, d’Ercole C, Floriot M, Fontaine P, Fournier A, Gillet JY, Gin H, Grandperret-Vauthier S, Geudj AM, Guionnet B, Hauguel-de-Mouzon S, Hieronimus S, Hoffet M, Jullien D, Lamotte MF, Lejeune V, Lepercq J, Lorenzi F, Mares P, Miton A, Penfornis A, Pfister B, Renard E, Rodier M, Roth P, Sery GA, Timsit J, Valat AS, Vambergue A, Verier-Mine O (2003) French multicentric survey of outcome of pregnancy in women with pregestational diabetes. Diabetes Care 26(11):2990–2993

    Article  PubMed  Google Scholar 

  • Catalano PM, Ehrenberg HM (2006) The short- and long-term implications of maternal obesity on the mother and her offspring. BJOG 113(10):1126–1133

    Article  PubMed  CAS  Google Scholar 

  • Coetzee EJ, Jackson WP (1985) The management of non-insulin-dependent diabetes during pregnancy. Diabetes Res Clin Pract 1(5):281–287

    Article  PubMed  Google Scholar 

  • Coetzee EJ, Levitt NS (2000) Maternal diabetes and neonatal outcome. Semin Neonatol 5(3):221–229

    Article  PubMed  CAS  Google Scholar 

  • Cundy T, Gamble G, Townend K, Henley PG, MacPherson P, Roberts AB (2000) Perinatal mortality in type 2 diabetes mellitus. Diabet Med 17(1):33–39

    Article  PubMed  CAS  Google Scholar 

  • Dahlquist GG, Nystrom L, Patterson CC (2011) Incidence of type 1 diabetes in Sweden among individuals aged 0–34 years, 1983–2007: an analysis of time trends. Diabetes Care 34(8):1754–1759

    Article  PubMed  Google Scholar 

  • Danaei G, Finucane MM, Lu Y, Singh GM, Cowan MJ, Paciorek CJ, Lin JK, Farzadfar F, Khang YH, Stevens GA, Rao M, Ali MK, Riley LM, Robinson CA, Ezzati M (2011) National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2.7 million participants. Lancet 378(9785):31–40

    Article  PubMed  CAS  Google Scholar 

  • Diamond project group (2006) Incidence and trends of childhood type 1 diabetes worldwide 1990–1999. Diabet Med 23(8):857–866

    Article  Google Scholar 

  • Ekpebegh CO, Coetzee EJ, van der Merwe L, Levitt NS (2007) A 10-year retrospective analysis of pregnancy outcome in pregestational Type 2 diabetes: comparison of insulin and oral glucose-lowering agents. Diabet Med 24(3):253–258

    Article  PubMed  CAS  Google Scholar 

  • Engelgau MM, Herman WH, Smith PJ, German RR, Aubert RE (1995) The epidemiology of diabetes and pregnancy in the U.S., 1988. Diabetes Care 18(7):1029–1033

    Article  PubMed  CAS  Google Scholar 

  • Evers IM, de Valk HW, Visser GH (2004) Risk of complications of pregnancy in women with type 1 diabetes: nationwide prospective study in the Netherlands. BMJ 328(7445):915

    Article  PubMed  Google Scholar 

  • Finucane MM, Stevens GA, Cowan MJ, Danaei G, Lin JK, Paciorek CJ, Singh GM, Gutierrez HR, Lu Y, Bahalim AN, Farzadfar F, Riley LM, Ezzati M (2011) National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9.1 million participants. Lancet 377(9765):557–567

    Article  PubMed  Google Scholar 

  • Flegal KM, Carroll MD, Kuczmarski RJ, Johnson CL (1998) Overweight and obesity in the United States: prevalence and trends, 1960–1994. Int J Obes Relat Metab Disord 22(1):39–47

    Article  PubMed  CAS  Google Scholar 

  • Flegal KM, Carroll MD, Ogden CL, Curtin LR (2010) Prevalence and trends in obesity among US adults, 1999–2008. JAMA 303(3):235–241

    Article  PubMed  CAS  Google Scholar 

  • Gabbe SG, Mestman JH, Hibbard LT (1976) Maternal mortality in diabetes mellitus: an 18-year survey. Obstet Gynecol 48(5):549–551

    PubMed  CAS  Google Scholar 

  • Gale EA (2002) The rise of childhood type 1 diabetes in the 20th century. Diabetes 51(12):3353–3361

    Article  PubMed  CAS  Google Scholar 

  • Gale EA (2005) Spring harvest? Reflections on the rise of type 1 diabetes. Diabetologia 48(12):2445–2450

    Article  PubMed  CAS  Google Scholar 

  • Heslehurst N, Ells LJ, Simpson H, Batterham A, Wilkinson J, Summerbell CD (2007) Trends in maternal obesity incidence rates, demographic predictors, and health inequalities in 36,821 women over a 15-year period. BJOG 114(2):187–194

    Article  PubMed  CAS  Google Scholar 

  • Heslehurst N, Rankin J, Wilkinson JR, Summerbell CD (2010) A nationally representative study of maternal obesity in England, UK: trends in incidence and demographic inequalities in 619 323 births, 1989–2007. Int J Obes (Lond) 34(3):420–428

    Article  CAS  Google Scholar 

  • International Diabetes Federation (2011) The diabetes atlas, 4th edn. International Diabetes Federation, Brussels

    Google Scholar 

  • Johnstone FD, Lindsay RS, Steel J (2006) Type 1 diabetes and pregnancy: trends in birth weight over 40 years at a single clinic. Obstet Gynecol 107(6):1297–1302

    Article  PubMed  CAS  Google Scholar 

  • Jovanovic L, Peterson CM (1980) Management of the pregnant, insulin-dependent diabetic woman. Diabetes Care 3(1):63–68

    Article  PubMed  CAS  Google Scholar 

  • Kanagalingam MG, Forouhi NG, Greer IA, Sattar N (2005) Changes in booking body mass index over a decade: retrospective analysis from a Glasgow Maternity Hospital. BJOG 112(10):1431–1433

    Article  PubMed  Google Scholar 

  • Kuczmarski RJ, Flegal KM, Campbell SM, Johnson CL (1994) Increasing prevalence of overweight among US adults. The National Health and Nutrition Examination Surveys, 1960 to 1991. JAMA 272(3):205–211

    Article  PubMed  CAS  Google Scholar 

  • Macintosh MC, Fleming KM, Bailey JA, Doyle P, Modder J, Acolet D, Golightly S, Miller A (2006) Perinatal mortality and congenital anomalies in babies of women with type 1 or type 2 diabetes in England, Wales, and Northern Ireland: population based study. BMJ 333(7560):177

    Article  PubMed  Google Scholar 

  • National Audit Office (2001) Tackling obesity in England. National Audit Office, London

    Google Scholar 

  • Ogden CL, Carroll MD, Curtin LR, Lamb MM, Flegal KM (2010) Prevalence of high body mass index in US children and adolescents, 2007–2008. JAMA 303(3):242–249

    Article  PubMed  CAS  Google Scholar 

  • Patterson CC, Dahlquist GG, Gyurus E, Green A, Soltesz G (2009) Incidence trends for childhood type 1 diabetes in Europe during 1989–2003 and predicted new cases 2005–20: a multicentre prospective registration study. Lancet 373(9680):2027–2033

    Article  PubMed  Google Scholar 

  • Penney GC, Mair G, Pearson DW (2003) Outcomes of pregnancies in women with type 1 diabetes in Scotland: a national population-based study. BJOG 110(3):315–318

    Article  PubMed  Google Scholar 

  • Rangasami JJ, Greenwood DC, McSporran B, Smail PJ, Patterson CC, Waugh NR (1997) Rising incidence of type 1 diabetes in Scottish children, 1984–93. The Scottish Study Group for the Care of Young Diabetics. Arch Dis Child 77(3):210–213

    Article  PubMed  CAS  Google Scholar 

  • Renehan AG, Tyson M, Egger M, Heller RF, Zwahlen M (2008) Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies. Lancet 371(9612):569–578

    Article  PubMed  Google Scholar 

  • Vaarasmaki MS, Hartikainen A, Anttila M, Pramila S, Koivisto M (2000) Factors predicting peri- and neonatal outcome in diabetic pregnancy. Early Hum Dev 59(1):61–70

    Article  PubMed  CAS  Google Scholar 

  • Wang YC, McPherson K, Marsh T, Gortmaker SL, Brown M (2011) Health and economic burden of the projected obesity trends in the USA and the UK. Lancet 378(9793):815–825

    Article  PubMed  Google Scholar 

  • Yanovski SZ, Yanovski JA (2011) Obesity prevalence in the United States–up, down, or sideways? N Engl J Med 364(11):987–989

    Article  PubMed  CAS  Google Scholar 

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Correspondence to Robert Lindsay Ph.D., FRCP(Glasg) .

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© 2012 Springer-Verlag Berlin Heidelberg

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Lindsay, R. (2012). Epidemiology of Diabetes and Obesity in Pregnancy. In: Ovesen, P., Møller Jensen, D. (eds) Maternal Obesity and Pregnancy. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-25023-1_1

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  • DOI: https://doi.org/10.1007/978-3-642-25023-1_1

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-25022-4

  • Online ISBN: 978-3-642-25023-1

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