Abstract
In the general population, increases in type 2 diabetes and obesity are apparent in many countries. In some societies, particularly the USA, rises have been very marked. Incidence of type 1 diabetes in childhood has also been noted to be increasing, albeit less dramatically. These secular trends have clear and important implications for those caring for women during pregnancy as the numbers of women with diabetes present before pregnancy will increase. Women with type 1 diabetes will likely have longer duration of disease by the time they fall pregnant. Type 2 diabetes, which in many countries was a relatively uncommon condition in pregnancy, is rapidly becoming commoner than type 1 diabetes as co-morbidity of pregnancy. Increases in obesity in the population will also increase the likelihood of gestational diabetes (diabetes with first onset or recognition in pregnancy). In this chapter, I will review secular increases in diabetes and obesity and how these increases have been translated into changes in the pregnant population.
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Boulot P, Chabbert-Buffet N, d’Ercole C, Floriot M, Fontaine P, Fournier A, Gillet JY, Gin H, Grandperret-Vauthier S, Geudj AM, Guionnet B, Hauguel-de-Mouzon S, Hieronimus S, Hoffet M, Jullien D, Lamotte MF, Lejeune V, Lepercq J, Lorenzi F, Mares P, Miton A, Penfornis A, Pfister B, Renard E, Rodier M, Roth P, Sery GA, Timsit J, Valat AS, Vambergue A, Verier-Mine O (2003) French multicentric survey of outcome of pregnancy in women with pregestational diabetes. Diabetes Care 26(11):2990–2993
Catalano PM, Ehrenberg HM (2006) The short- and long-term implications of maternal obesity on the mother and her offspring. BJOG 113(10):1126–1133
Coetzee EJ, Jackson WP (1985) The management of non-insulin-dependent diabetes during pregnancy. Diabetes Res Clin Pract 1(5):281–287
Coetzee EJ, Levitt NS (2000) Maternal diabetes and neonatal outcome. Semin Neonatol 5(3):221–229
Cundy T, Gamble G, Townend K, Henley PG, MacPherson P, Roberts AB (2000) Perinatal mortality in type 2 diabetes mellitus. Diabet Med 17(1):33–39
Dahlquist GG, Nystrom L, Patterson CC (2011) Incidence of type 1 diabetes in Sweden among individuals aged 0–34 years, 1983–2007: an analysis of time trends. Diabetes Care 34(8):1754–1759
Danaei G, Finucane MM, Lu Y, Singh GM, Cowan MJ, Paciorek CJ, Lin JK, Farzadfar F, Khang YH, Stevens GA, Rao M, Ali MK, Riley LM, Robinson CA, Ezzati M (2011) National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2.7 million participants. Lancet 378(9785):31–40
Diamond project group (2006) Incidence and trends of childhood type 1 diabetes worldwide 1990–1999. Diabet Med 23(8):857–866
Ekpebegh CO, Coetzee EJ, van der Merwe L, Levitt NS (2007) A 10-year retrospective analysis of pregnancy outcome in pregestational Type 2 diabetes: comparison of insulin and oral glucose-lowering agents. Diabet Med 24(3):253–258
Engelgau MM, Herman WH, Smith PJ, German RR, Aubert RE (1995) The epidemiology of diabetes and pregnancy in the U.S., 1988. Diabetes Care 18(7):1029–1033
Evers IM, de Valk HW, Visser GH (2004) Risk of complications of pregnancy in women with type 1 diabetes: nationwide prospective study in the Netherlands. BMJ 328(7445):915
Finucane MM, Stevens GA, Cowan MJ, Danaei G, Lin JK, Paciorek CJ, Singh GM, Gutierrez HR, Lu Y, Bahalim AN, Farzadfar F, Riley LM, Ezzati M (2011) National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9.1 million participants. Lancet 377(9765):557–567
Flegal KM, Carroll MD, Kuczmarski RJ, Johnson CL (1998) Overweight and obesity in the United States: prevalence and trends, 1960–1994. Int J Obes Relat Metab Disord 22(1):39–47
Flegal KM, Carroll MD, Ogden CL, Curtin LR (2010) Prevalence and trends in obesity among US adults, 1999–2008. JAMA 303(3):235–241
Gabbe SG, Mestman JH, Hibbard LT (1976) Maternal mortality in diabetes mellitus: an 18-year survey. Obstet Gynecol 48(5):549–551
Gale EA (2002) The rise of childhood type 1 diabetes in the 20th century. Diabetes 51(12):3353–3361
Gale EA (2005) Spring harvest? Reflections on the rise of type 1 diabetes. Diabetologia 48(12):2445–2450
Heslehurst N, Ells LJ, Simpson H, Batterham A, Wilkinson J, Summerbell CD (2007) Trends in maternal obesity incidence rates, demographic predictors, and health inequalities in 36,821 women over a 15-year period. BJOG 114(2):187–194
Heslehurst N, Rankin J, Wilkinson JR, Summerbell CD (2010) A nationally representative study of maternal obesity in England, UK: trends in incidence and demographic inequalities in 619 323 births, 1989–2007. Int J Obes (Lond) 34(3):420–428
International Diabetes Federation (2011) The diabetes atlas, 4th edn. International Diabetes Federation, Brussels
Johnstone FD, Lindsay RS, Steel J (2006) Type 1 diabetes and pregnancy: trends in birth weight over 40 years at a single clinic. Obstet Gynecol 107(6):1297–1302
Jovanovic L, Peterson CM (1980) Management of the pregnant, insulin-dependent diabetic woman. Diabetes Care 3(1):63–68
Kanagalingam MG, Forouhi NG, Greer IA, Sattar N (2005) Changes in booking body mass index over a decade: retrospective analysis from a Glasgow Maternity Hospital. BJOG 112(10):1431–1433
Kuczmarski RJ, Flegal KM, Campbell SM, Johnson CL (1994) Increasing prevalence of overweight among US adults. The National Health and Nutrition Examination Surveys, 1960 to 1991. JAMA 272(3):205–211
Macintosh MC, Fleming KM, Bailey JA, Doyle P, Modder J, Acolet D, Golightly S, Miller A (2006) Perinatal mortality and congenital anomalies in babies of women with type 1 or type 2 diabetes in England, Wales, and Northern Ireland: population based study. BMJ 333(7560):177
National Audit Office (2001) Tackling obesity in England. National Audit Office, London
Ogden CL, Carroll MD, Curtin LR, Lamb MM, Flegal KM (2010) Prevalence of high body mass index in US children and adolescents, 2007–2008. JAMA 303(3):242–249
Patterson CC, Dahlquist GG, Gyurus E, Green A, Soltesz G (2009) Incidence trends for childhood type 1 diabetes in Europe during 1989–2003 and predicted new cases 2005–20: a multicentre prospective registration study. Lancet 373(9680):2027–2033
Penney GC, Mair G, Pearson DW (2003) Outcomes of pregnancies in women with type 1 diabetes in Scotland: a national population-based study. BJOG 110(3):315–318
Rangasami JJ, Greenwood DC, McSporran B, Smail PJ, Patterson CC, Waugh NR (1997) Rising incidence of type 1 diabetes in Scottish children, 1984–93. The Scottish Study Group for the Care of Young Diabetics. Arch Dis Child 77(3):210–213
Renehan AG, Tyson M, Egger M, Heller RF, Zwahlen M (2008) Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies. Lancet 371(9612):569–578
Vaarasmaki MS, Hartikainen A, Anttila M, Pramila S, Koivisto M (2000) Factors predicting peri- and neonatal outcome in diabetic pregnancy. Early Hum Dev 59(1):61–70
Wang YC, McPherson K, Marsh T, Gortmaker SL, Brown M (2011) Health and economic burden of the projected obesity trends in the USA and the UK. Lancet 378(9793):815–825
Yanovski SZ, Yanovski JA (2011) Obesity prevalence in the United States–up, down, or sideways? N Engl J Med 364(11):987–989
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Lindsay, R. (2012). Epidemiology of Diabetes and Obesity in Pregnancy. In: Ovesen, P., Møller Jensen, D. (eds) Maternal Obesity and Pregnancy. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-25023-1_1
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DOI: https://doi.org/10.1007/978-3-642-25023-1_1
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