When Should Preoperative Short-Course Radiotherapy or Long-Course Chemoradiotherapy Be Performed?

  • David Sebag-Montefiore
  • Robert Glynne-Jones


Traditionally, there has been a high local recurrence rate after radical surgery in rectal cancer, and 10–40% of patients require a permanent stoma. Both short-course preoperative radiotherapy (SCPRT) and long-course preoperative chemoradiation (CRT) are advocated to reduce this risk of local recurrence and enable a curative resection. The role of preoperative radiotherapy to facilitate sphincter sparing surgery remains highly contentious.


Rectal Cancer Total Mesorectal Excision Late Toxicity Circumferential Resection Margin Mesorectal Fascia 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  1. 1.Department of Clinical OncologyUniversity of Leeds, St James’s Institute of Oncology, St James’s University HospitalLeedsUK
  2. 2.Department of Clinical OncologyMount Vernon Centre for Cancer TreatmentNorthwood, MiddlesexUK

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