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Lymph Nodes

  • Peter Spieler
  • Matthias Rössle
Part of the Essentials of Diagnostic Pathology book series (ESSENTPATH)

Abstract

A first section covers fine needle aspiration techniques, aspects of sample processing, basic aspects of ancillary analyses including a synopsis of CD-markers, and architecture and cytology of normal lymph nodes.

Cytologic criteria of common benign lymphoid disorders are presented in section 2.

The third section primarily focuses on basic diagnostic rules regarding malignant lymphoid disorders, and comprises (1) comprehensive cytologic description of the most important varieties of malignant lymphomas and myeloproliferative disorders, and (2) consideration on histiocytic sarcoma. For each entity, special attention is paid to immunophenotyping and molecular genetic studies. Furthermore, a table is included which displays common non-lymphoid immunocyto-chemical tumor cell markers and their diagnostic use on metastatic disease.

Cytodiagnostic algorithms of benign and malignant lymphoid lesions and their respective differential diagnoses are additionally presented in synoptic setups.

Keywords

Follicular Lymphoma Hodgkin Lymphoma Mantle Cell Lymphoma Anaplastic Lymphoma Kinase Myeloproliferative Disorder 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Further Reading

Further Reading (Sect. 15.1)

  1. 1.
    Aiello ADD, Giardini R, Alasio L, et al. PCR analysis of IgH and BCL2 gene rearrangement in the diagnosis of follicular lymphoma in lymph node fine-needle aspiration. A critical appraisal. Diagn Mol Pathol 1997;6:154-160.PubMedCrossRefGoogle Scholar
  2. 2.
    Alcan SLC, Sarago C, Sidawy MK, et al. Polymerase chain reaction detection of immunoglobulin gene rearrangement and bcl-2 translocation in archival glass slides of cytologic material. Diagn Mol Pathol 1995;4:25-31.CrossRefGoogle Scholar
  3. 3.
    Bangerter M, Brudler O, Heinrich B, Griesshammer M. Fine needle aspiration cytology and flow cytometry in the diagnosis and subclassification of non-Hodgkin’s lymphoma based on the World Health Organization Classification. Acta Cytol2007;51:390-398.PubMedCrossRefGoogle Scholar
  4. 4.
    Barroca H, Marques C, Candeias J.Fine needle aspiration cytology diagnosis, flow cytometry immunophenotyping and histology in clinically suspected lymphoproliferative disorder. A comparative study. Acta Cytol 2008;52:124-132.PubMedCrossRefGoogle Scholar
  5. 5.
    Caraway NP, Thomas E, Khanna A, et al. Chromosomal abnormalities detected by multicolor fluorescence in situ hybridization in fine-needle aspirates from patients with small lymphocytic lymphoma are useful for predicting survival. Cancer(Cancer Cytopathol) 2008;114:315-322.Google Scholar
  6. 6.
    Chen J-T, Lane MA, Clark DP. Inhibitors of the polymerase chain reaction in Papanicolaou stain. Removal with a simple destaining procedure. Acta Cytol 1996;40:873-877.PubMedCrossRefGoogle Scholar
  7. 7.
    Chhieng DC, Cohen JM, Cangiarella JF. Cytology and immunophenotyping of low- and intermediate-grade B-cell non Hodgkin’s lymphomas with a predominant small-cell component: a study of 56 cases. Diagn Cytopathol 2001;24:90-97.PubMedCrossRefGoogle Scholar
  8. 8.
    Das DK. Value and limitations of fine-needle aspiration cytology in diagnosis and classification of lymphomas: a review. Diagn Cytopathol 1999;21:240-249.PubMedCrossRefGoogle Scholar
  9. 9.
    Dey P. Role of ancillary techniques in diagnosing and subclassifying non-Hodgkin’s lymphomas on fine needle aspiration cytology. Cytopathology 2006;17:275-287.PubMedCrossRefGoogle Scholar
  10. 10.
    Dey P, Amir T, Al Jassar A, et al. Combined applications of fine needle aspiration cytology and flow cytometric immunophenotyping for diagnosis and classification of non-Hodgkin lymphoma. Cytojournal2006;3:24.PubMedCrossRefGoogle Scholar
  11. 11.
    Dong HY, Harris NL, Preffer FI, et al. Fine-needle aspiration biopsy in the diagnosis and classification of primary and recurrent lymphoma: a retrospective analysis of the utility of cytomorphology and flow cytometry. Mod Pathol 2001;14:472-481.PubMedCrossRefGoogle Scholar
  12. 12.
    Gall K, Pavicic D, Pavelic J, et al. PCR amplification of DNA from stained cytological smears. J Clin Pathol 1993;46:378-379.PubMedCrossRefGoogle Scholar
  13. 13.
    Garbar C, Remmelink M, Mascaux C. Fine needle aspiration cytology of lymph node: experience of 2 university hospitals with conventional smears and liquid-based cytology.Acta Cytol 2008;52: 418-423.PubMedCrossRefGoogle Scholar
  14. 14.
    Gong Y, Caraway N, Gu J, et al. Evaluation of interphase fluorescence in situ hybridization for the t(14;18)(q32;q21) translocation in the diagnosis of follicular lymphoma on fine-needle aspirates: a comparison with flow cytometry immunophenotyping.Cancer 2003;99:385-393.PubMedCrossRefGoogle Scholar
  15. 15.
    Gong JZ, Snyder MJ, Lagoo AS, et al. Diagnostic impact of coreneedle biopsy on fine-needle aspiration of non-Hodgkin lymphoma.Diagn Cytopathol 2004;31:23-30.PubMedCrossRefGoogle Scholar
  16. 16.
    Hanley KZ, Holden JT, Mosunjac MB. Fine-needle aspiration cytology of high-grade non-Hodgkin lymphomas - when flow cytometry does not support the diagnosis. (abstract)Cancer(Cancer Cytopathol) Suppl. 2008;114:418-419.Google Scholar
  17. 17.
    Jiang F, Katz RL. Use of interphase fluorescence in situ hybridization as a powerful diagnostic tool in cytology.Diagn Mol Pathol 2002;11:47-57.PubMedCrossRefGoogle Scholar
  18. 18.
    Kocjan G. Best Practice No 185: Cytological and molecular diagnosis of lymphoma. J Clin Pathol 2005;58:561-567.PubMedCrossRefGoogle Scholar
  19. 19.
    Kube MJ, McDonald DA, Quin JW, Greenberg ML. Use of archival and fresh cytologic material for the polymerase chain reaction. Analyt Quant Cytol Histol 1994;16:174-182.Google Scholar
  20. 20.
    Lennert K. Histopathologie der Non-Hodgkin-Lymphome (nach der Kiel Klassifikation). Springer Verlag Berlin-Heidelberg 1981.CrossRefGoogle Scholar
  21. 21.
    Lukes RJ, Collins RD.Afunctional approach to the classification of malignant lymphoma. Recent Results in Cancer Res1974;46:18-30.Google Scholar
  22. 22.
    Mathiot C, Decaudin D, Klijanienko J, et al. Fine-needle aspiration cytology combined with flow cytometry immunophenotyping is a rapid and accurate approach for the evaluation of suspicious superficial lymphoid lesions. Diagn Cytopathol 2006;34:472-478.PubMedCrossRefGoogle Scholar
  23. 23.
    Meda BA, Buss DH, Woodruff RD, et al. Diagnosis and subclassification of primary and recurrent lymphoma: the usefulness and limitations of combined fine-needle aspiration cytomorphology and flow cytometry.Am J Clin Pathol2000;113:688-699.PubMedCrossRefGoogle Scholar
  24. 24.
    Morris-Stiff G, Cheang P, Key S, et al. Does the surgeon still have aroletoplayinthediagnosisandmanagementoflymphomas?World J Surg Oncol 2008;6:13.PubMedCrossRefGoogle Scholar
  25. 25.
    Pugh JL, Jhala NC, Eloubeidi MA, et al. Diagnosis of deep-seated lymphoma and leukemia by endoscopic ultrasound-guided fineneedle aspiration biopsy. Am J Clin Pathol2006;125:703-709.PubMedCrossRefGoogle Scholar
  26. 26.
    Ribeiro A, Vazquez-Sequeiros E, Wiersema LM, et al. EUS-guided fine-needle aspiration combined with flow cytometry and immunocytochemistry in the diagnosis of lymphoma. Gastrointest Endosc 2001;53:485-491.PubMedCrossRefGoogle Scholar
  27. 27.
    Richmond J, Bryant R, Trotman W, et al. FISH detection of t(14;18) in follicular lymphoma on Papanicolaou-stained archival cytology slides.Cancer 2006;108:198-204.PubMedCrossRefGoogle Scholar
  28. 28.
    Roh JL, Lee YW, Kim JM. Clinical utility of fine-needle aspiration for diagnosis of head and neck lymphoma.Eur J Surg Oncol 2008;34:817-821.PubMedCrossRefGoogle Scholar
  29. 29.
    Safley AM, Buckley PJ, Creager AJ, et al. The value of fluorescence in situ hybridization and polymerase chain reaction in the diagnosis of B-cell non-Hodgkin lymphoma by fine-needle aspiration. Arch Pathol Lab Med 2004;128:1395-1403.PubMedGoogle Scholar
  30. 30.
    Sigstad E, Dong HP, Davidson B, et al. The role of flow cytometric immunophenotyping in improving the diagnostic accuracy in referred fine-needle aspiration specimens. Diagn Cytopathol 2004;31:159-163.PubMedCrossRefGoogle Scholar
  31. 31.
    Simsir A, Fetsch P, Stetler-Stevenson M, Abati A. Immunophenotypic analysis of non-Hodgkin’s lymphomas in cytologic specimens: a correlative study of immunocytochemical and flow cytometric techniques. Diagn Cytopathol 1999;20:278-284.PubMedCrossRefGoogle Scholar
  32. 32.
    Sneige N, Dekmezian RH, Katz RL, et al. Morphologic and immunocytochemical evaluation of 220 fine needle aspirates of malignant lymphoma and lymphoid hyperplasia.Acta Cytol 1990;34: 311-322.PubMedGoogle Scholar
  33. 33.
    Stewart CJR, Duncan JA, Farquharson M, Richmond J. Fine needle aspiration cytology diagnosis of malignant lymphoma and reactive lymphoid hyperplasia.J Clin Pathol 1998;51:197-203.PubMedCrossRefGoogle Scholar
  34. 34.
    Torlakovic E, Berner A, Risberg B. Detection of immunoglobulin heavy chain gene rearrangements by polymerase chain reaction analysis on lymph node imprints and fine-needle aspirate smears: a comparison of five different imprint preparations. Diagn Cytopathol 1999;20:333-338.PubMedCrossRefGoogle Scholar
  35. 35.
    Venkatraman L, Catherwood MA, Patterson A, et al. Role of polymerase chain reaction and immunocytochemistry in the cytological assessment of lymphoid proliferations. J Clin Pathol 2006;59:1160-1165.PubMedCrossRefGoogle Scholar

Further Reading (Sect. 15.2)

  1. 1.
    Alvarez Alegret R, Martinez Tello A, Ramirez T, et al. Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease): diagnosis with fine-needle aspiration in a case with nodal and nasal involvement. Diagn Cytopathol 1995;13:333-335.PubMedCrossRefGoogle Scholar
  2. 2.
    Bart PA, Meuwly JY, Corpataux JM, et al. Sampling lymphoid tissue cells by ultrasound-guided fine needle aspiration of lymph nodes in HIV-infected patients. Swiss HIV Cohort Study. AIDS 1999;13:1503-1509.PubMedCrossRefGoogle Scholar
  3. 3.
    Bezabih M, Mariam DW, Selassie SG. Fine needle aspiration cytology of suspected tuberculous lymphadenitis. Cytopathology 2002;13:284-290.PubMedCrossRefGoogle Scholar
  4. 4.
    Castleman B, Iverson L, Menendez VP. Localized mediastinal lymph node hyperplasia resembling thymoma. Cancer 1956;9: 822–30.PubMedCrossRefGoogle Scholar
  5. 5.
    Chen HC, Kang BH, Lai CT, Lin YS. Sarcoidal granuloma in cervical lymph nodes. J Chin Med Assoc 2005;68:339-342.PubMedCrossRefGoogle Scholar
  6. 6.
    Daneshbod Y, Daneshbod K, Khademi B, et al. New cytologic clues in localized Leishmania lymphadenitis. Acta Cytol 2007;51:699-710.PubMedCrossRefGoogle Scholar
  7. 7.
    Deshpande V, Verma K. Fine needle aspiration (FNA) cytology of Rosai Dorfman disease. Cytopathology 1998;9:329-335.PubMedCrossRefGoogle Scholar
  8. 8.
    Donnelly A, Hendricks G, Martens S, et al. Cytologic diagnosis of cat scratch disease (CSD) by fine-needle aspiration. Diagn Cytopathol 1995;13:103-106.PubMedCrossRefGoogle Scholar
  9. 9.
    Dorfman RF, Warnke R. Lymphadenopathy simulating the malignant lymphomas. Human Pathol 1974;5:519-550.CrossRefGoogle Scholar
  10. 10.
    Edelweiss M, Medeiros LJ, Suster S, Moran CA. Lymph node involvement by Langerhans cell histiocytosis: a clinicopathologic and immunohistochemical study of 20 cases. Hum Pathol 2007;38:1463-1469.PubMedCrossRefGoogle Scholar
  11. 11.
    Ersöz C, Polat A, Serin MS, et al. Fine needle aspiration (FNA) cytology in tuberculous lymphadenitis. Cytopathology 1998;9:201-207.PubMedCrossRefGoogle Scholar
  12. 12.
    Gaitonde S. Multifocal, extranodal sinus histiocytosis with massive lymphadenopathy: an overview. Arch Pathol Lab Med 2007;131:1117-1121.PubMedGoogle Scholar
  13. 13.
    Garbyal RS, Basu D, Roy S, Kumar P. Cryptococcal lymphadenitis: report of a case with fine needle aspiration cytology. Acta Cytol 2005;49:58-60.PubMedCrossRefGoogle Scholar
  14. 14.
    Gupta RK. Fine needle aspiration cytodiagnosis of toxoplasmic lymphadenitis. Acta Cytol 1997;41:1031-1034.PubMedCrossRefGoogle Scholar
  15. 15.
    Hjalgrim H, Askling J, Rostgaard K, et al. Characteristics of Hodgkin’s lymphoma after infectious mononucleosis. N Engl J Med 2003;349:1324-1332.PubMedCrossRefGoogle Scholar
  16. 16.
    Iyer VK, Kapila K, Verma K. Fine needle aspiration cytology of dermatopathic lymphadenitis. Acta Cytol 1998;42:1347-1351.PubMedCrossRefGoogle Scholar
  17. 17.
    Jayaram G, Chew MT. Fine needle aspiration cytology of lymph nodes in HIV-infected individuals. Acta Cytol 2000;44:960-966.PubMedCrossRefGoogle Scholar
  18. 18.
    Kakkar S, Kapila K, Verma K. Langerhans cell histiocytosis in lymph nodes. Cytomorphologic diagnosis and pitfalls. Acta Cytol 2001;45:327-332.PubMedCrossRefGoogle Scholar
  19. 19.
    Kardos TF, Kornstein MJ, Frable WJ. Cytology and immunocytology of infectious mononucleosis in fine needle aspiration of lymph nodes. Acta Cytol 1988;32:722-726.PubMedGoogle Scholar
  20. 20.
    Khurana KK, Stanley MW, Powers CN, Pitman MB. Aspiration cytology of malignant neoplasms associated with granulomas and granuloma-like features: diagnostic dilemmas. Cancer 1998;84:84-91.PubMedCrossRefGoogle Scholar
  21. 21.
    Kojima M, Morita Y, Shimizu K, et al. Plasmacytoid monocytes in cat scratch disease with special reference to the histological diversity of suppurative lesions. Pathol Res Pract 2006;202:17-22.PubMedCrossRefGoogle Scholar
  22. 22.
    Koo V, Lioe TF, Spence RA. Fine needle aspiration cytology (FNAC) in the diagnosis of granulomatous lymphadenitis. Ulster Med J 2006;75:59-64.PubMedGoogle Scholar
  23. 23.
    Kumar B, Karki S, Paudyal P. Diagnosis of sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease) by fine needle aspiration cytology. Diagn Cytopathol 2008;36:691-695.PubMedCrossRefGoogle Scholar
  24. 24.
    Kumar PV, Moosavi A, Karimi M, et al. Subclassification of localized Leishmania lymphadenitis in fine needle aspiration smears. Acta Cytol 2001;45:547-554.PubMedCrossRefGoogle Scholar
  25. 25.
    Kumar PV, Mousavi A, Karimi M, Bedayat GR. Fine needle aspiration of Langerhans cell histiocytosis of the lymph nodes. A report of six cases. Acta Cytol 2002;46:753-756.PubMedCrossRefGoogle Scholar
  26. 26.
    Laane E, Tani E, Björklund E, et al. Flow cytometric immunophenotyping including Bcl-2 detection on fine needle aspirates in the diagnosis of reactive lymphadenopathy and non-Hodgkin’s lymphoma. Cytometry B Clin Cytom 2005;64:34-42.PubMedGoogle Scholar
  27. 27.
    Lamps LW, Scott MA. Cat-scratch disease: historic, clinical, and pathologic perspectives. Am J Clin Pathol 2004;121 Suppl:S71-80.PubMedGoogle Scholar
  28. 28.
    Mallik MK, Kapila K, Das DK, et al. Cytomorphology of hyalinevascular Castleman’s disease: a diagnostic challenge. Cytopathology 2007;18:168-174.PubMedGoogle Scholar
  29. 29.
    Martin-Bates E, Tanner A, Suvarna SK, et al. Use of fine needle aspiration cytology for investigating lymphadenopathy in HIV-positive patients. J Clin Pathol 1993;46:564-566.PubMedCrossRefGoogle Scholar
  30. 30.
    Oertel J, Oertel B, Lobeck H, Huhn D. Immunocytochemical analysis of lymph node aspirates in patients with human immunodeficiency virus infection. J Clin Pathol 1990;43:844-846.PubMedCrossRefGoogle Scholar
  31. 31.
    Ohsaki H, Nakamura M, Kagawa A, et al. Fine needle aspiration cytology of an enlarged inguinal lymph node. Cytopathology 2008;19:389-393.PubMedCrossRefGoogle Scholar
  32. 32.
    Osborn M, Aqel N, Levine TS. The fine needle aspiration appearances of Kikuchi’s lymphadenitis. Cytopathology 2009;20:36-43.PubMedCrossRefGoogle Scholar
  33. 33.
    Pai MR, Adhikari P, Coimbatore RV, Ahmed S. Fine needle aspiration cytology in systemic lupus erythematosus lymphadenopathy. A case report. Acta Cytol 2000;44:67-69.PubMedCrossRefGoogle Scholar
  34. 34.
    Pathan SK, Francis IM, Das DK, et al. Fine needle aspiration cytologic diagnosis of toxoplasma lymphadenitis. A case report with detection of a Toxoplasma bradycyst in a Papanicolaou-stained smear. Acta Cytol 2003;47:299-303.PubMedCrossRefGoogle Scholar
  35. 35.
    Pilotti S, Di Palma S, Alasio L, et al. Diagnostic assessment of enlarged superficial lymph nodes by fine needle aspiration. Acta Cytol 1993;37:853-866.PubMedGoogle Scholar
  36. 36.
    Rajasekharan P, Narurkar S, Patel K, Rajpal A. Asteroid bodies in a lymph node aspirate. A case report. Acta Cytol 2007;51:66-67.PubMedCrossRefGoogle Scholar
  37. 37.
    Renshaw AA. Reporting risk of malignancy/dysplasia in cytology. A potential way to improve communication, if not reputation. Cancer (Cancer Cytopathol) 2007;111:465-466.Google Scholar
  38. 38.
    Robertson S, Kovitz KL, Moroz K. Disseminated coccidioidomycosis. The role of cytology in multidisciplinary clinical approach and diagnosis. J La State Med Soc 1999;151:409-413.PubMedGoogle Scholar
  39. 39.
    Sah SP, Prasad R, Raj GA. Fine needle aspiration of lymphadenopathy in visceral leishmaniasis. Acta Cytol 2005;49:286-290.PubMedCrossRefGoogle Scholar
  40. 40.
    Saikia UN, Dey P, Jindal B, Saikia B. Fine needle aspiration cytology in lymphadenopathy of HIV-positive cases. Acta Cytol 2001;45:589-592.PubMedCrossRefGoogle Scholar
  41. 41.
    Shapiro AL, Pincus RL. Fine-needle aspiration of diffuse cervical lymphadenopathy in patients with acquired immunodeficiency syndrome. Otolaryngol Head Neck Surg 1991;105:419-421.PubMedGoogle Scholar
  42. 42.
    Shimizu K, Ito I, Sasaki H, et al. Fine needle aspiration of toxoplasmic lymphadenitis in an intramammary lymph node. A case report. Acta Cytol 2001;45:259-262.PubMedCrossRefGoogle Scholar
  43. 43.
    Shiran MS, Tan GC, Kenali MS, et al. Multifocal nodal and extranodal Rosai-Dorfman disease initially diagnosed as histiocytic lymphoma. Malays J Pathol 2008;30:63-65.PubMedGoogle Scholar
  44. 44.
    Silverman JF. Fine needle aspiration cytology of cat scratch disease. Acta Cytol 1985;29:542-547.PubMedGoogle Scholar
  45. 45.
    Sivakumar S. Role of fine needle aspiration cytology in detection of microfilariae: report of 2 cases. Acta Cytol 2007;51:803-806.PubMedCrossRefGoogle Scholar
  46. 46.
    Sneige N, Dekmezian RH, Katz RL, et al. Morphologic and immunocytochemical evaluation of 220 fine needle aspirates of ma-lignant lymphoma and lymphoid hyperplasia. Acta Cytol 1990;34: 311-322.PubMedGoogle Scholar
  47. 47.
    Stani J. Cytologic diagnosis of reactive lymphadenopathy in fine needle aspiration biopsy specimens. Acta Cytol 1987;31:8-13.PubMedGoogle Scholar
  48. 48.
    Stanley MW, Steeper TA, Horwitz CA, et al. Fine-needle aspiration of lymph nodes in patients with acute infectious mononucleosis. Diagn Cytopathol 1990;6:323-329.PubMedCrossRefGoogle Scholar
  49. 49.
    Steel BL, Schwartz MR, Ramzy I. Fine needle aspiration biopsy in the diagnosis of lymphadenopathy in 1103 patients. Role, limitations and analysis of diagnostic pitfalls. Acta Cytol 1995;39:76-81.PubMedGoogle Scholar
  50. 50.
    Stewart CJR, Duncan JA, Farquharson M, Richmond J. Fine needle aspiration cytology diagnosis of malignant lymphoma and reactive lymphoid hyperplasia. J Clin Pathol 1998;51:197-203.PubMedCrossRefGoogle Scholar
  51. 51.
    Sudilovsky D, Cha I. Fine needle aspiration cytology of dermatopathic lymphadenitis. Acta Cytol 1998;42:1341-1346.PubMedCrossRefGoogle Scholar
  52. 52.
    Tambouret R, Geisinger KR, Powers CN, et al. The clinical application and cost analysis of fine-needle aspiration biopsy in the diagnosis of mass lesions in sarcoidosis. Chest 2000;117:1004-1011.PubMedCrossRefGoogle Scholar
  53. 53.
    Tong TR, Chan OW, Lee KC. Diagnosing Kikuchi disease on fine needle aspiration biopsy: a retrospective study of 44 cases diagnosedbycytologyand8byhistopathology.ActaCytol2001;45:953-957.Google Scholar
  54. 54.
    Tsang WY, Chan JK. Fine-needle aspiration cytologic diagnosis of Kikuchi’s lymphadenitis. A report of 27 cases. Am J Clin Pathol 1994;102:454-458.PubMedGoogle Scholar
  55. 55.
    Tuon FF, Gomes V, Pagliari C, et al. Isolated lymphadenitis due to Histoplasma capsulatum diagnosed by fine-needle aspiration biopsy and immunohistochemistry. Rev Iberoam Micol 2008;25:50-51.PubMedCrossRefGoogle Scholar
  56. 56.
    Viguer JM, Jimenez-Heffernan JA, Lopez-Ferrer P, et al. Fine needle aspiration of toxoplasmic (Piringer-Kuchinka) lymphadenitis: a cytopathologic correlation study. Acta Cytol 2005;49:139-143.PubMedCrossRefGoogle Scholar
  57. 57.
    Viguer JM, Jimenez-Heffernan JA, Perez P, et al. Fine-needle aspiration cytology of Kikuchi’s lymphadenitis: a report of ten cases. Diagn Cytopathol 2001;25:220-224.PubMedCrossRefGoogle Scholar
  58. 58.
    Wakely PE Jr, Silverman JF, Holbrook CT, et al. Fine needle aspiration biopsy cytology as an adjunct in the diagnosis of childhood sarcoidosis. Pediatr Pulmonol 1992;13:117-120.PubMedCrossRefGoogle Scholar
  59. 59.
    Zaharopoulos P. Demonstration of parasites in toxoplasma lymphadenitis by fine-needle aspiration cytology: report of two cases. Diagn Cytopathol 2000;22:11-15.PubMedCrossRefGoogle Scholar
  60. 60.
    Zaharopoulos P, Hudnall SD. Nevus-cell aggregates in lymph nodes: fine-needle aspiration cytologic findings and resulting diagnostic difficulties. Diagn Cytopathol 2004;31:180-184.PubMedCrossRefGoogle Scholar
  61. 61.
    Zardawi IM, Barker BJ, Simons DP. Hodgkin’s disease masquerading as granulomatous lymphadenitis on fine needle aspiration cytology. Acta Cytol 2005;49:224-226.PubMedGoogle Scholar

Further Reading (Sect. 15.3)

  1. 1.
    Ali EA, Boerner SL, Geddie WR, et al. Grading B-cell Non-Hodgkin lymphoma using MIB-1 proliferative index in fine needle aspirates. 2008; 114 Suppl:445.Google Scholar
  2. 2.
    Al Shanqeety O, Mourad WA. Diagnosis of peripheral T-cell lymphoma by fine-needle aspiration biopsy: a cytomorphologic and immunophenotypic approach. Diagn Cytopathol 2000;23:375-379.PubMedCrossRefGoogle Scholar
  3. 3.
    Bahler DW, Swerdlow SH. Clonal salivary gland infiltrates associated with myoepithelial sialadenitis (Sjögren’s syndrome) begin as nonmalignant antigen-selected expansions. Blood 1998;91:1864-1872.PubMedGoogle Scholar
  4. 4.
    Bangerter M, Brudler O, Heinrich B, Griesshammer M. Fine needle aspiration cytology and flow cytometry in the diagnosis and subclassification of non-Hodgkin’s lymphoma based on the World Health Organization Classification. Acta Cytol 2007;51:390-398.PubMedCrossRefGoogle Scholar
  5. 5.
    Bangerter M, Hildebrand A, Waidmann O, Griesshammer M. Diagnosis of granulocytic sarcoma by fine-needle aspiration cytology. Acta Haematol 2000;103:102-108.PubMedCrossRefGoogle Scholar
  6. 6.
    Bangerter M, Hildebrand A, Waidmann O, Griesshammer M. Fine needle aspiration cytology in extramedullary plasmacytoma. Acta Cytol 2000;44:287-291.PubMedCrossRefGoogle Scholar
  7. 7.
    Basu D, Kumar S, Shome DK, Chauhan S. Cutaneous T-cell lymphoma diagnosed by fine-needle aspiration: a case report with clinical, cytological, and immunophenotypic features. Diagn Cytopathol 1994;11:174-177.PubMedCrossRefGoogle Scholar
  8. 8.
    Bentz JS, Rowe LR, Anderson SR, et al. Rapid detection of the t(11;14) translocation in mantle cell lymphoma by interphase fluorescence in situ hybridisation on archival cytopatholgic material. Cancer 2004;102:124-131.PubMedCrossRefGoogle Scholar
  9. 9.
    Caraway NP, Gu J, Lin P, et al. The utility of interphase fluorescence in situ hybridisation for the detection of the translocation t(11;14)(q13;q32) in the diagnosis of mantle cell lymphoma on fine-needle aspiration specimens. Cancer 2005;105:110-118.PubMedCrossRefGoogle Scholar
  10. 10.
    Caraway NP, Thomas E, Khanna A, et al. Chromosomal abnormalities detected by multicolor fluorescence in situ hybridization in fine-needle aspirates from patients with small lymphocytic lymphoma are useful for predicting survival. Cancer(Cancer Cytopathol) 2008;114:315-322.Google Scholar
  11. 11.
    Carbone A, Gloghini A, Ferlito A. Pathological features of lymphoid proliferations of the salivary glands: lymphoepithelial sialadenitis versus low-grade B-cell lymphoma of the MALT type. Ann Otol Rhinol Laryngol 2000;109:1170-1175.PubMedGoogle Scholar
  12. 12.
    Chhieng DC, Cohen J-M, Cangiarella JF. Cytology and immunophenotyping of low- and intermediate-grade B-cell non-Hodgkin’s lymphomas with a predominant small-cell component: A stuy of 56 cases. Diagn Cytopathol 2001;24:90-97.PubMedCrossRefGoogle Scholar
  13. 13.
    Chhieng DC, Cangiarella JF, Symmans WF, Cohen JM. Fine-needle aspiration cytology of Hodgkin disease: a study of 89 cases with emphasis on false-negative cases. Cancer 2001;93:52-59.PubMedCrossRefGoogle Scholar
  14. 14.
    Cogliatti SB, Novak U, Henz S, et al. Diagnosis of Burkitt lymphoma in due time: a practical approach. Brit J Haematol 2006;134:294-301.CrossRefGoogle Scholar
  15. 15.
    Copie-Bergman C, Wotherspoon AC, Norton AJ, et al. True histiocytic lymphoma: a morpholgic, immunohistochemical, and molecular genetic study of 13 cases. Am J Surg Pathol 1998;22:1386-1392PubMedCrossRefGoogle Scholar
  16. 16.
    Crapanzano JP, Lin O. Cytologic findings of marginal zone lymphoma. Cancer 2003;99:301-309.PubMedCrossRefGoogle Scholar
  17. 17.
    Das DK. Value and limitations of fine-needle aspiration cytology in diagnosis and classification of lymphomas: a review. Diagn Cytopathol 1999;21:240-249.PubMedCrossRefGoogle Scholar
  18. 18.
    Das DK, Gupta SK, Datta BN, Sharma SC. Fine needle aspiration cytodiagnosis of Hodgkin’s disease and its subtypes. I. Scope and limitations. Acta Cytol 1990;34:329-336.PubMedGoogle Scholar
  19. 19.
    Dave SS, Fu K, Wright GW, et al. Molecular diagnosis of Burkitt’s lymphoma. N Engl J Med 2006;354:2431-2442.PubMedCrossRefGoogle Scholar
  20. 20.
    de Almeida MM, Chagas M, de Sousa JV, Mendonca ME. Fineneedle aspiration cytology as a tool for the early detection of testicular relapse of acute lymphoblastic leukemia in children. Diagn Cytopathol 1994;10:44-46.PubMedCrossRefGoogle Scholar
  21. 21.
    Del Giudice I, Matutes E, Morilla R, et al. The diagnostic value of CD123 in B-cell disorders with hairy or villous lymphocytes. Haematologica 2004;89:303-308.PubMedGoogle Scholar
  22. 22.
    Dey P. Role of ancillary techniques in diagnosing and subclassifying non-Hodgkin’s lymphomas on fine needle aspiration cytology. Cytopathology 2006;17:275-287.PubMedCrossRefGoogle Scholar
  23. 23.
    Dey P, Radhika S, Das A. Fine-needle aspiration biopsy of angioimmunoblastic lymphadenopathy. Diagn Cytopathol 1996;15:412-414.PubMedCrossRefGoogle Scholar
  24. 24.
    Folk GS, Abbondanzo SL, Childers EL, Foss RD. Plasmablastic lymphoma: a clinicopathologic correlation. Ann Diagn Pathol 2006;10:8-12.PubMedCrossRefGoogle Scholar
  25. 25.
    Galindo LM, Garcia FU, Hanau CA, et al. Fine-needle aspiration biopsy in the evaluation of lymphadenopathy associated with cutaneous T-cell lymphoma (mycosis fungoides/Sézary syndrome). Am J Clin Pathol 2000;113:865-871.PubMedCrossRefGoogle Scholar
  26. 26.
    Gong JZ, Stenzel TT, Bennett ER, et al. Burkitt lymphoma arising in organ transplant recipients: a clinicopathologic study of five cases. Am J Surg Pathol 2003;27:818-827.PubMedCrossRefGoogle Scholar
  27. 27.
    Gong JZ, Williams DC Jr, Liu K, Jones C. Fine-needle aspiration in non-Hodgkin lymphoma: evaluation of cell size by cytomorphology and flow cytometry. Am J Clin Pathol 2002;117:880-888.PubMedCrossRefGoogle Scholar
  28. 28.
    Gong Y, Caraway N, Gu J, et al. Evaluation of interphase fluorescence in situ hybridization for the t(14;18)(q32;q21) translocation in the diagnosis of follicular lymphoma on fine-needle aspirates: a comparison with flow cytometry immunophenotyping. Cancer 2003;99:385-393.PubMedCrossRefGoogle Scholar
  29. 29.
    Gujral S, Kumar R, Jain P, et al. Fine needle aspiration of extramedullary myeloid cell tumor in myelodysplastic syndrome. A report of three cases. Acta Cytol 1999;43:647-651.PubMedCrossRefGoogle Scholar
  30. 30.
    Huang KP, Weinstock MA, Clarke CA, et al. Second lymphomas and other malignant neoplasms in patients with mycosis fungoides and Sézary syndrome: evidence from population-based and clinical cohorts. Arch Dermatol 2007;143:45-50.PubMedCrossRefGoogle Scholar
  31. 31.
    Hummel M, Bentink S, Berger H, et al. A biologic definition of Burkitt’s lymphoma from transcriptional and genomic profiling. N Engl J Med 2006;354:2419-2430.PubMedCrossRefGoogle Scholar
  32. 32.
    Iacobuzio-Donahue CA, Clark DP, Ali SZ. Reed-Sternberg-like cells in lymph node aspirates in the absence of Hodgkin’s disease: pathologic significance and differential diagnosis. Diagn Cytopathol 2002;27:335-339.PubMedCrossRefGoogle Scholar
  33. 33.
    Iyengar KR, Mutha S. Discrete epithelioid cells: useful clue to Hodgkin’s disease cytodiagnosis. Diagn Cytopathol 2002;26:142-144.PubMedCrossRefGoogle Scholar
  34. 34.
    Jacobs JC, Katz RL, Shabb N, et al. Fine needle aspiration of lymphoblastic lymphoma. A multiparameter diagnostic approach. Acta Cytol 1992;36:887-894.PubMedGoogle Scholar
  35. 35.
    Jaffe ES, Zarate-Osorno A, Kingma DW, et al. The interrelationship between Hodgkin’s disease and non-Hodgkin’s lymphomas. Ann Oncol 1994;5 Suppl 1:7-11.PubMedGoogle Scholar
  36. 36.
    Jeffers MD, Milton J, Herriot R, McKean M. Fine needle aspiration cytology in the investigation of non-Hodgkin’s lymphoma. J Clin Pathol 1998;51:189-196.PubMedCrossRefGoogle Scholar
  37. 37.
    Jimenez-Heffernan JA, Vicandi B, Lopez-Ferrer P, et al. Value of fine needle aspiration cytology in the initial diagnosis of Hodgkin’s disease. Analysis of 188 cases with emphasis on diagnostic pitfalls. Acta Cytol 2001;45:300-306.PubMedCrossRefGoogle Scholar
  38. 38.
    Jogai S, Dey P, Al Jassar A, et al. Role of fine needle aspiration cytology in nodular sclerosis variant of Hodgkin’s lymphoma. Acta Cytol 2006;50:507-512.PubMedCrossRefGoogle Scholar
  39. 39.
    Kardos TF, Sprague RI, Wakely PE Jr, Frable WJ. Fine-needle aspiration biopsy of lymphoblastic lymphoma and leukemia. A clinical, cytologic, and immunologic study. Cancer 1987;60:2448-2453.PubMedCrossRefGoogle Scholar
  40. 40.
    Katz RL, Gritsman A, Cabanillas F, et al. Fine-needle aspiration cytology of peripheral T-cell lymphoma. Am J Clin Pathol 1989;91:120-131.PubMedGoogle Scholar
  41. 41.
    Kishimoto K, Kitamura T, Fujita K, et al. Cytologic differential diagnosis of follicular lymphoma grades 1 and 2 from reactive follicular hyperplasia: cytologic features of fine-needle aspiration smears with Pap stain and fluorescence in situ hybridization analysis to detect t(14;18)(q32;q21) chromosomal translocation. Diagn Cytopathol 2006;34:11-17.PubMedCrossRefGoogle Scholar
  42. 42.
    Koch CA, Li CY, Mesa RA, Tefferi A. Nonhepatosplenic extramedullary hematopoiesis: associated diseases, pathology, clinical course, and treatment. Mayo Clin Proc 2003;78:1223-1233.PubMedCrossRefGoogle Scholar
  43. 43.
    Kocjan G. Best Practice No 185: Cytological and molecular diagnosis of lymphoma. J Clin Pathol 2005;58:561-567.PubMedCrossRefGoogle Scholar
  44. 44.
    Kojima M, Nakamura S, Motoori T, et al. Primary marginal zone B-cell lymphoma of the lymphnode resembling plasmacytoma arising from a plasma cell variant of Castleman’s disease. A clinicopathological and immunohistochemical study of seven patients. APMIS 2002;110:875-880.PubMedCrossRefGoogle Scholar
  45. 45.
    Kollur SM, El Hag IA. Fine-needle aspiration cytology of metastatic nasopharyngeal carcinoma in cervical lymph nodes: comparison with metastatic squamous-cell carcinoma, and Hodgkin’s and non-Hodgkin’s lymphoma. Diagn Cytopathol 2003;28:18-22.PubMedCrossRefGoogle Scholar
  46. 46.
    Kost CB, Holden JT, Mann KP. Marginal zone B-cell lymphoma: a retrospective immunophenotypic analysis. Cytometry B Clin Cytom 2008;74:282-286.PubMedGoogle Scholar
  47. 47.
    Laane E, Tani E, Björklund E, et al. Flow cytometric immunophenotyping including Bcl-2 detection on fine needle aspirates in the diagnosis of reactive lymphadenopathy and non-Hodgkin’s lymphoma. Cytometry B Clin Cytom 2005;64:34-42.PubMedGoogle Scholar
  48. 48.
    Lacroix A, Jaccard A, Rouzioux C, et al. HHV-6 and EBV DNA quantitation in lymph nodes of 86 patients with Hodgkin’s lymphoma. J Med Virol 2007;79:1349-1356.PubMedCrossRefGoogle Scholar
  49. 49.
    Lin O, Gerhard R, Zerbini MC, Teruya-Feldstein J. Cytologic features of plasmablastic lymphoma. Cancer 2005;105:139-144.PubMedCrossRefGoogle Scholar
  50. 50.
    Mann R, Berard C. Criteria for the cytologic subclassification of follicular lymphomas: a proposed alternative method. Hematol Oncol 1982;1:187-192.CrossRefGoogle Scholar
  51. 51.
    Mathiot C, Decaudin D, Klijanienko J, et al. Fine-needle aspiration cytology combined with flow cytometry immunophenotyping is a rapid and accurate approach for the evaluation of suspicious superficial lymphoid lesions. Diagn Cytopathol 2006;34:472-478.PubMedCrossRefGoogle Scholar
  52. 52.
    Mathur S, Dawar R, Verma K. Diagnosis and grading of non-Hodgkin’s lymphomas on fine needle aspiration cytology. Indian J Pathol Microbiol 2007;50:46-50.PubMedGoogle Scholar
  53. 53.
    Matsushima AY, Hamele-Bena D, Osborne BM. Fine-needle aspiration biopsy findings in marginal zone B cell lymphoma. Diagn Cytopathol 1999;20:190-198.PubMedCrossRefGoogle Scholar
  54. 54.
    Matutes E. Adult T-cell leukaemia/lymphoma. J Clin Pathol 2007;60:1373-1377.PubMedCrossRefGoogle Scholar
  55. 55.
    McCluggage WG, Anderson N, Herron B, Caughley L. Fine needle aspiration cytology, histology and immunohistochemistry of anaplastic large cell Ki-1-positive lymphoma. A report of three cases. Acta Cytol 1996;40:779-785.PubMedCrossRefGoogle Scholar
  56. 56.
    Meara RS, Reddy V, Arnoletti JP, et al. Hairy cell leukemia: a diagnosis by endoscopic ultrasound guided fine needle aspiration. Cytojournal 2006;3:1.PubMedCrossRefGoogle Scholar
  57. 57.
    Miliauskas JR. Fine-needle aspiration cytology: true histiocytic lymphoma/histiocytic sarcoma. Diagn Cytopathol 2003;29:233-235.PubMedCrossRefGoogle Scholar
  58. 58.
    Moriarty AT, Schwenk GR Jr, Chua G. Splenic fine needle aspiration biopsy in the diagnosis of lymphoreticular diseases. A report of four cases. Acta Cytol 1993;37:191-196.PubMedGoogle Scholar
  59. 59.
    Mourad WA, Sneige N, Huh YO, et al. Fine needle aspiration cytology of extramedullary chronic myelogenous leukemia. Acta Cytol 1995;39:706-712.PubMedGoogle Scholar
  60. 60.
    Murphy BA, Meda BA, Buss DH, Geisinger KR. Marginal zone and mantle cell lymphomas: assessment of cytomorphology in subtyping small B-cell lymphomas. Diagn Cytopathol 2003;28:126-130.PubMedCrossRefGoogle Scholar
  61. 61.
    Nakamura N, Nakamine H, Tamaru J, et al. The distinction between Burkitt lymphoma and diffuse large B-cell lymphoma with c-myc rearrangement. Mod Pathol 2002;15:771-776.PubMedCrossRefGoogle Scholar
  62. 62.
    Ng WK, Ip P, Choy C, Collins RJ. Cytologic findings of angioimmunoblastic T-cell lymphoma: analysis of 16 fine-needle aspirates over 9-year period. Cancer 2002;96:166-173.PubMedCrossRefGoogle Scholar
  63. 63.
    Ng WK, Ip P, Choy C, Collins RJ. Cytologic and immunocytochemical findings of anaplastic large cell lymphoma: analysis of ten fine-needle aspiration specimens over a 9-year period. Cancer 2003;99:33-43.PubMedCrossRefGoogle Scholar
  64. 64.
    Ngu IW, Sinclair EC, Greenaway S, Greenberg ML. Unusual presentation of granulocytic sarcoma in the breast: a case report and review of the literature. Diagn Cytopathol 2001;24:53-57.PubMedCrossRefGoogle Scholar
  65. 65.
    Orucevic A, Reddy VB, Selvaggi SM, et al. Fine-needle aspiration of extranodal and extramedullary hematopoietic malignancies. Diagn Cytopathol 2000;23:318-321.PubMedCrossRefGoogle Scholar
  66. 66.
    Owen RG, Treon SP, Al Katib A, et al. Clinicopathological definition of Waldenstrom’s macroglobulinemia: consensus panel recommendations from the Second International Workshop on Waldenstrom’s macroglobulinemia. Semin Oncol 2003;30:110-115.PubMedCrossRefGoogle Scholar
  67. 67.
    Pai RK, Mullins FM, Kim YH, Kong CS. Cytologic evaluation of lymphadenopathy associated with mycosis fungoides and Sézary syndrome. Role of immunophenotypic and molecular ancillary studies. Cancer(Cancer Cytopathol) 2008;114:323-332.Google Scholar
  68. 68.
    Park IA, Kim CW. FNAC of malignant lymphoma in an area with a high incidence of T-cell lymphoma. Correlation of accuracy of cytologic diagnosis with histologic subtype and immunophenotype. Acta Cytol 1999;43:1059-1069.PubMedCrossRefGoogle Scholar
  69. 69.
    Paydas S, Zorludemir S, Ergin M. Granulocytic sarcoma: 32 cases and review of the literature. Leuk Lymphoma 2006;47:2527-2541.PubMedCrossRefGoogle Scholar
  70. 70.
    Pilotti S, Di Palma S, Alasio L, et al. Diagnostic assessment of enlarged superficial lymph nodes by fine needle aspiration. Acta Cytol 1993;37:853-866.PubMedGoogle Scholar
  71. 71.
    Pinto RG, Rocha PD, Vernekar JA. Fine needle aspiration of the spleen in hairy cell leukemia.Acase report.Acta Cytol 1995;39:777-780.PubMedGoogle Scholar
  72. 72.
    Pinto AE, Cabecadas J, Nobrega SD Mendonca E. Flow-cytometric S-phase fraction as a complementary biological parameter for the cytological grading of non-Hodgkin’s lymphoma. Diagn Cytopathol 2003;29:194-199.PubMedCrossRefGoogle Scholar
  73. 73.
    Policarpio-Nicolas ML, Bregman SG, Ihsan M, Atkins KA. Massforming extramedullary hematopoiesis diagnosed by fine-needle aspiration cytology. Diagn Cytopathol 2006;34:807-811.PubMedCrossRefGoogle Scholar
  74. 74.
    Pugh JL, Jhala NC, Eloubeidi MA, et al. Diagnosis of deep-seated lymphoma and leukemia by endoscopic ultrasound-guided fineneedle aspiration biopsy. Am J Clin Pathol 2006;125:703-709. 75.PubMedCrossRefGoogle Scholar
  75. 75.
    Raab SS, Silverman JF, McLeod DL, Geisinger KR. Fine-needle aspiration cytology of extramedullary hematopoiesis (myeloid metaplasia). Diagn Cytopathol 1993;9:522-526.PubMedCrossRefGoogle Scholar
  76. 76.
    Rapkiewicz A, Wen H, Sen F, Das K. Cytomorphologic examination of anaplastic large cell lymphoma by fine-needle aspiration cytology. Cancer(Cancer Cytopathol) 2007;111:499-507.Google Scholar
  77. 77.
    Rassidakis GZ, Tani E, Svedmyr E, et al. Diagnosis and subclassification of follicular center and mantle cell lymphomas on fineneedle aspirates: a cytologic and immunocytochemical approach based on the Revised European-American Lymphoma (REAL) classification. Cancer 1999;87:216-223.PubMedCrossRefGoogle Scholar
  78. 78.
    Reid-Nicholson M, Kavuri S, Ustun C, et al. Plasmablastic lymphoma: cytologic findings in 5 cases with unusual presentation. Cancer(Cancer Cytopathol) 2008;114:333-341.Google Scholar
  79. 79.
    Renshaw AA. Reporting risk of malignancy/ dysplasia in cytology. A potential way to improve communication, if not reputation. Cancer (Cancer Cytopathol) 2007;111:465-466.Google Scholar
  80. 80.
    Saikia UN, Dey P, Saikia B, Das A. Fine-needle aspiration biopsy in diagnosis of follicular lymphoma: cytomorphologic and immunohistochemical analysis. Diagn Cytopathol 2002;26:251-256.PubMedCrossRefGoogle Scholar
  81. 81.
    Skoog L, Tani E. The role of fine-needle aspiration cytology in the diagnosis of non-Hodgkin’s lymphoma. Diagn Oncol 1991;1:12-18.Google Scholar
  82. 82.
    Sneige N, Dekmezian RH, Katz RL, et al. Morphologic and immunocytochemical evaluation of 220 fine needle aspirates of malignant lymphoma and lymphoid hyperplasia. Acta Cytol 1990;34:311-322.PubMedGoogle Scholar
  83. 83.
    Spieler P, Schmid U. How exact are the diagnosis and classification of malignant lymphomas from aspiration biopsy smears? A comparison between histologic and cytologic diagnoses of 20 Hodgkin’s and 54 non-Hodgkin’s lymphomas according to Rappaport (1966) and Kiel (1974) nomenclatures. Path Res Pract 1978;163:232-250.PubMedCrossRefGoogle Scholar
  84. 84.
    Stanley MW, Powers CN. Syncytial variant of nodular sclerosing Hodgkin’s disease: fine-needle aspiration findings in two cases. Diagn Cytopathol 1997;17:477-479.PubMedCrossRefGoogle Scholar
  85. 85.
    Steel BL, Schwartz MR, Ramzy I. Fine needle aspiration biopsy in the diagnosis of lymphadenopathy in 1103 patients. Role, limitations and analysis of diagnostic pitfalls. Acta Cytol 1995;39:76-81.PubMedGoogle Scholar
  86. 86.
    Stewart CJR, Duncan JA, Farquharson M, Richmond J. Fine needle aspiration cytology diagnosis of malignant lymphoma and reactive lymphoid hyperplasia. J Clin Pathol 1998;51:197-203.PubMedCrossRefGoogle Scholar
  87. 87.
    Suh YK, Shin HJ. Fine-needle aspiration biopsy of granulocytic sarcoma: a clinicopathologic study of 27 cases. Cancer 2000;90:364-372.PubMedCrossRefGoogle Scholar
  88. 88.
    Swerdlow SH, Campo E, Harris NL, et al. (Eds.). WHO Cassification of Tumours of Haematopoietic and Lymphoid Tissues. IARC: Lyon 2008.Google Scholar
  89. 89.
    Tao J, Wu M, Fuchs A, Wasserman P. Fine-needle aspiration of granulocytic sarcomas: a morphologic and immunophenotypic study of seven cases. Ann Diagn Pathol 2000;4:17-22.PubMedCrossRefGoogle Scholar
  90. 90.
    Thieblemont C. Clinical presentation and management of marginal zone lymphomas. Hematology Am Soc Hematol Educ Program 2005;307-313.Google Scholar
  91. 91.
    Tiemann M, Asbeck R, Wacker HH. Clonal B-cell reaction in Sjögren disease and Hashimoto autoimmune thyroiditis. Pathologe 1996;17:289-295.PubMedCrossRefGoogle Scholar
  92. 92.
    Tong TR, Lee KC, Chow TC, et al. T-cell/histiocyte-rich diffuse large B-cell lymphoma. Report of a case diagnosed by fine needle aspiration biopsy with immunohistochemical and molecular pathologic correlation. Acta Cytol 2002;46:893-898.PubMedCrossRefGoogle Scholar
  93. 93.
    Traverse-Glehen A, Felman P, Callet-Bauchu E, et al. A clinicopathological study of nodal marginal zone B-cell lymphoma. A report on 21 cases. Histopathology 2006;48:162-173.PubMedCrossRefGoogle Scholar
  94. 94.
    Troxell ML, Bangs CD, Cherry AM, et al. Cytologic diagnosis of Burkitt lymphoma. Cancer 2005;105:310-318.PubMedCrossRefGoogle Scholar
  95. 95.
    Uherova P, Ross CW, Finn WG, et al. Peripheral T-cell lymphoma mimicking marginal zone B-cell lymphoma. Mod Pathol 2002;15:420-425.PubMedCrossRefGoogle Scholar
  96. 96.
    Vaillo A, Gutierrez-Martin A, Ballestin C, Ruiz-Liso JM. Marginal zone B-cell lymphoma of the parotid gland associated with epithelioid granulomas. Report of a case with fine needle aspiration. Acta Cytol 2004;48:420-424.PubMedCrossRefGoogle Scholar
  97. 97.
    Vaillo Vinagre A, Gutierrez MA, Perez Barrios A, et al. Lymphoepithelioid cell lymphoma (Lennert’s lymphoma). Report of a case with fine needle aspiration cytology.Acta Cytol 2004;48:234-238.PubMedCrossRefGoogle Scholar
  98. 98.
    Vicandi B, Jimenez-Heffernan JA, Lopez-Ferrer P, et al. Hodgkin’s disease mimicking suppurative lymphadenitis: a fine-needle aspiration report of five cases. Diagn Cytopathol 1999;20:302-306.PubMedCrossRefGoogle Scholar
  99. 99.
    Vos JA, Abbondanzo SL, Barekman CL, et al. Histiocytic sarcoma: a study of five cases including the histiocyte marker CD163. Mod Pathol 2005;18:693-704.PubMedCrossRefGoogle Scholar
  100. 100.
    Wakely P Jr, Frable WJ, Kneisl JS. Soft tissue aspiration cytopathology of malignant lymphoma and leukemia. Cancer 2001;93:35-39.PubMedCrossRefGoogle Scholar
  101. 101.
    Wakely PE Jr, Kornstein MJ. Aspiration cytopathology of lymphoblastic lymphoma and leukemia: the MCV experience. Pediatr Pathol Lab Med 1996;16:243-252.PubMedCrossRefGoogle Scholar
  102. 102.
    Yao JL, Cangiarella JF, Cohen JM, Chhieng DC. Fine-needle aspiration biopsy of peripheral T-cell lymphomas. A cytologic and immunophenotypic study of 33 cases. Cancer 2001;93:151-159.PubMedCrossRefGoogle Scholar
  103. 103.
    Yashima-Abo A, Satoh T, Abo T, et al. Distinguishing between proliferating nodal lymphoid blasts in chronic myelogenous leukemia and non-Hodgkin lymphoma: report of three cases and detection of a bcr/abl fusion signal by single-cell analysis. Pathol Int 2005;55:273-279.PubMedCrossRefGoogle Scholar
  104. 104.
    Young NA, Al-Saleem TI, Al-Saleem Z, et al. The value of transformed lymphocyte count in subclassification of non-Hodgkin’s lymphoma by fine-needle aspiration. Am J Clin Pathol 1997;108:143-151.PubMedGoogle Scholar
  105. 105.
    Zardawi IM, Barker BJ, Simons DP. Hodgkin’s disease masquerading as granulomatous lymphadenitis on fine needle aspiration cytology. Acta Cytol 2005;49:224-226.PubMedGoogle Scholar
  106. 106.
    Zardawi IM, Jain S, Bennet G. Flow-cytometric algorithm on fine-needle aspirates for the clinical workup of patients with lymphadenopathy. Diagn Cytopathol 1998;19:274-278.PubMedCrossRefGoogle Scholar
  107. 107.
    Zhang JR, Raza AS, Greaves TS, Cobb CJ. Fine-needle aspiration diagnosis of Hodgkin lymphoma using current WHO classification – re-evaluation of cases from 1999-2004 with new proposals. Diagn Cytopathol 2006;34:397-402.PubMedCrossRefGoogle Scholar
  108. 108.
    Zhao FX. Nodular lymphocyte-predominant Hodgkin lymphoma or T-cell/histiocyte rich large B-cell lymphoma: the problem in “grey zone” lymphomas. Int J Clin Exp Pathol 2008;1:300-305.PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • Peter Spieler
    • 1
  • Matthias Rössle
    • 2
  1. 1.Institut für PathologieKantonsspital St. GallenSt. GallenSwitzerland
  2. 2.Institut für Klinische PathologieUniversitätsSpital ZürichZürichSwitzerland

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