Reconfigurable Hardware Computing for Accelerating Protein Folding Simulations Using the Harmony Search Algorithm and the 3D-HP-Side Chain Model
Proteins are essentials to life and they have countless biological functions. They are synthesized in the ribosome of cells following a template given by the messenger RNA (mRNA). During the synthesis, the protein folds into an unique three-dimensional structure, known as native conformation. This process is called protein folding. Several diseases are believed to be result of the accumulation of ill-formed proteins.Therefore, understanding the folding process can lead to important medical advancements and development of new drugs.
KeywordsHarmony Search Harmony Search Algorithm Harmony Memory Pitch Adjust Rate Functional Block Diagram
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