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Synthesis of Heck Coupling Partner for the Preparation of Heteroaromatic Lipoxin A4 Analogues

  • Colm Duffy
Chapter
Part of the Springer Theses book series (Springer Theses)

Abstract

Our research group recently developed a short and efficient synthetic route for the preparation of novel stable benzene-containing Lipoxin A4 and Lipoxin B4 analogues. One of the key synthetic steps relies on the construction of a trans double bond via a palladium-catalysed Heck reaction, a reliable and powerful method for the assembly of this class of alkene.

Keywords

Cumene Hydroperoxide Allylic Alcohol Ammonium Chloride Solution Copper Iodide Allyl Acetate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg  2012

Authors and Affiliations

  1. 1.UCD School of Chemistry and Chemical Biology, Centre for Synthesis and Chemical BiologyUniversity College DublinBelfield, Dublin 4Ireland

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