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Recent Advances in the Chemistry and Biology of Stable Synthetic Lipoxin Analogues

  • Colm Duffy
Chapter
Part of the Springer Theses book series (Springer Theses)

Abstract

The Lipoxin metabolites dramatically reduce the bioactivity of this class of compounds and render them poor potential pharmacological agents. In light of the findings associated with the stabilisation and market value of the synthetic prostaglandin and prostacyclin analogues, it was thought that a similar approach could be beneficial with respect to the native Lipoxins (LX).

Keywords

Boronic Acid Heck Reaction Aryl Bromide Boronic Ester Sonogashira Coupling 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg  2012

Authors and Affiliations

  1. 1.UCD School of Chemistry and Chemical Biology, Centre for Synthesis and Chemical BiologyUniversity College DublinBelfield, Dublin 4Ireland

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