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Rasayana Therapy and Rejuvenation

  • Ram Harsh Singh
  • Sanjeev Rastogi
Chapter

Abstract

Rasayana is an important aspect of Ayurvedic therapeutics where drugs and formulations are used to improve the quality of life by improving the tissue quality and by reducing the age-related tissue degeneration. Rasayana therapeutics has got its own comprehensive yet traditional know-how of indications, methods of use, and formulations. We have come across many studies exploring the possible mechanisms of action of such rasayana drugs for their health-promotive and disease-preventive role. To make rasayana a dependable and reproducible method of intervention from Ayurveda, it however still requires a substantial sum of work. An evidence-based practice of rasayana would come as an eventuality if we are able to answer the questions about its mechanism, indication, suitability, and actual end points of the therapy in the form of primary and secondary outcomes. This chapter reviews the concept of rasayana in Ayurveda and gleams into the future needs to make it a more dependable form of therapy from Ayurveda.

Keywords

Andrographis Paniculata Phyllanthus Emblica Senile Change Health Care Modality Antiaging Effect 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Caraka (700 BC) Caraka Samhita. Sharma PV (ed) Cikitsa Sthana, Chapter I, Pada 1–4. Choukhamba Orientalia, VaranasiGoogle Scholar
  2. 2.
    Sarangadhara (1300 AD) Sarangadhara Samhita Khand II, Chapter 6, vs. 20. Choukhmbha Prakasana, VaranasiGoogle Scholar
  3. 3.
    Susruta Samhita, Singhal GD & Associates (eds) Cikitsa Sthana, Chapters 27–30. Choukhamba Surbharati, Varanasi/New DelhiGoogle Scholar
  4. 4.
    Udupa KN, Singh RH (1974) Science and philosophy of Indian medicine. Sri Baidyanath Ayurveda Bhawan, NagpurGoogle Scholar
  5. 5.
    Vagbhatt (300 AD) Astanga Hridaya Uttara Tantra, Chapter 39 on Rasayana. Choukhamba Prakasan, VaranasiGoogle Scholar
  6. 6.
    Vagbhatta (300 AD) Astanga Sangraha Uttara Tantra, Rasayana Chapter. Choukhamba Publications, VaranasiGoogle Scholar
  7. 7.
    Singh RH (2005) Advances in Ayurvedic medicine, vol 1–5. Chaukhamba Vishwabharati, VaranasiGoogle Scholar
  8. 8.
    Singh RH (2005) Kayachikitsa, vol. I, Chap. 13 on Rasayana. Choukhambha Surbharati, VaranasiGoogle Scholar
  9. 9.
    Singh RH (2005) Swasthavrtta Vigyana, Chaps. 3, 4, 7, 22–23. Choukhamba Surbharati, VaranasiGoogle Scholar
  10. 10.
    Singh RH (2009) Mind-body-spirit integrative medicine. Choukhamba Surbharati, VaranasiGoogle Scholar
  11. 11.
    Singh RH and Associates (2008) Advances in Ayurvedic Medicine, vol 1–5. Choukhamba Vishwabharati, VaranasiGoogle Scholar
  12. 12.
    Singh RH, Narsimhamurthy K, Singh G (2008) Neuronutrient impact of Ayurvedic rasayana therapy in brain aging. Biogerontology 9:369–374PubMedCrossRefGoogle Scholar
  13. 13.
    Singh RH (2010) Rasayana therapy and rejuvenation. In: Singh RH (ed) Manual of geriatric health care through Ayurveda. Department of AYUSH, Govt. of India, New DelhiGoogle Scholar
  14. 14.
    Strength of Ayurveda in geriatric health care. Key Note Lecture by Singh RH, Launching National Campaign on Geriatric Health Care, Department of AYUSH, Ministry of Health, Government of India, 2008Google Scholar
  15. 15.
    Singh RH (2005) Pancakarma therapy. Choukhambha Sanskrit Series, VaranasiGoogle Scholar
  16. 16.
    Agrawal SC, Singh RH (1998) Effect of Medhya Rasayana drug, Mandukaparni (Centella asiatica) on cognitive functions and social adaptability in mental retardation. J Res Ayur Siddha 18:97–107Google Scholar
  17. 17.
    Archana R, Namasiwayam A (1999) Antistress effect of Withania somnifera. J Ethnopharmacol 64:91–93PubMedCrossRefGoogle Scholar
  18. 18.
    Bhattacharya SK et al (1997) Anxiolytic activity of Glyco-withanolides from Withania somnifera (Ashwagandha). J Exp Biol 35:236Google Scholar
  19. 19.
    Caraka (700 BC) Caraka Samhita. In: Sharma PV (ed) Cikitsa Sthana, Chap. I, Pada 1–4. Pub Choukhamba Orientalia, VaranasiGoogle Scholar
  20. 20.
    Choudhary MI et al (2004) Cholinesterase inhibiting Withanolides from Withania somnifera. Chem Pharm Bull (Tokyo) 52:1358–1361CrossRefGoogle Scholar
  21. 21.
    Dwivedi KK, Singh RH (1997) A study on geriatric patients and response of Ashwagandha as anti-aging agent. Ph.D. Thesis, Kayachikitsa, Banaras Hindu UniversityGoogle Scholar
  22. 22.
    Holcomb L et al (2006) Bacopa monnieri extract reduces Amyloid levels in PSAPP mice. J Alzheimers Dis 9:251Google Scholar
  23. 23.
    Kuboyama T et al (2005) Neuritic regeneration and synaptic reconstruction induced by Withanolide-A. Br J Pharmacol 144:961–971PubMedCrossRefGoogle Scholar
  24. 24.
    Pathak SR, Singh RH (1986) Study on influence of some plant products on brain function. Ph.D. Thesis (Ayu-Zoology), Banaras Hindu University, Varanasi, IndiaGoogle Scholar
  25. 25.
    Singh HK, Dhawan BN (1997) Neuropsychopharmacological studies on Brahmi. Indian J Pharmacol 29:5359–5365Google Scholar
  26. 26.
    Singh L, Singh RH (1978) Study on psychotropic effect of Brahmi (Bacopa monnieri). M.D. Ay. Thesis, Banaras Hindu University, Varanasi, IndiaGoogle Scholar
  27. 27.
    Singh N (1987) Study of Antistress effect of plant drugs. Ann Acad Ind Med 1(1):1–15Google Scholar
  28. 28.
    Sharma HM, Hanna AN, Kauffman EM, Newman HAI (1992) Inhibition of human low density lipoprotein oxidation in vitro by maharshi Ayurveda herbal mixtures. Pharmacol Biochem Behav 43:1175–1182PubMedCrossRefGoogle Scholar
  29. 29.
    Rekha PS, Kuttan G, Kuttan R (2001) Effect of brahma Rasayana on antioxidant system after radiation. Indian J Exp Biol 39:1173–1175PubMedGoogle Scholar
  30. 30.
    Puri HS (2003) Rasayana—Ayurvedic herbs for longevity and rejuvenation. Taylor and Francis, LondonCrossRefGoogle Scholar
  31. 31.
    Govindarajan R, Vijayakumar M, Pushpagandan P (2005) Antioxidant approach to disease management and the role of Rasayana herbs of Ayurveda. J Ethnopharmacol 99:165–178PubMedCrossRefGoogle Scholar
  32. 32.
    Narasingarao B (2003) Bioactive phytochemicals in Indian foods and their potential in health promotion and disease prevention. Asia Pac J Clin Nutr 12:9–22Google Scholar
  33. 33.
    Priyadarshini S, Ashadevi JS, Nagarjun V, Prasanna KS (2010) Increase in Drosophila melanogaster longevity due to rasayana diet: Preliminary results. J Ayur Integr Med 1:114–119CrossRefGoogle Scholar
  34. 34.
    Priyandoko D, Ishii T, Kaul SC, Wadhwa R (2011) Ashwagandha leaf derived Withanone protects normal human cells against the toxicity of methoxyacetic acid, a major industrial metabolite. PLoS One 6:e19552. doi: 10.1371/journal.pone.0019552 PubMedCrossRefGoogle Scholar
  35. 35.
    Prasad R (2011) Evaluation of immunomodulation by Withania Somnifera used as an adjunct DOTS-RNTCP to chemotherapy for increased effectiveness in pulmonary-tuberculosis patients. Available at http://www.cstup.gov.in/pdfs/MedicalSc.pdf. Accessed on 15 May 2011
  36. 36.
    Rastogi S (2010) Building bridges between Ayurveda and modern science. Int J Ayur Res 1:41–46CrossRefGoogle Scholar
  37. 37.
    Balasubramani SP, Venkatasubramanian P, Kukkupuni SK, Patwardhan B (2011) Plant-based Rasayana drugs from Ayurveda. Chin J Integr Med 17:88–94, Epub 9 Mar 2011PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  1. 1.Department of Kaya Chikitsa, Institute of Medical SciencesBanaras Hindu UniversityVaranasiIndia
  2. 2.PG Department of Kaya Chikitsa, State Ayurvedic CollegeLucknow UniversityLucknowIndia

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