Projection X-Space MPI Mouse Scanner

  • Patrick Goodwill
  • Justin Konkle
  • Bo Zheng
  • Steven Conolly
Part of the Springer Proceedings in Physics book series (SPPHY, volume 140)

Abstract

Here we describe the construction and images of the first projection x-space MPI scanner. The scanner is a side-access quadrupole design, and generates a 2.35 T/m main field gradient. The system excites the sample and receives signal in one axis, and reconstructs full-body images using x-space reconstruction. The resulting images are of high quality, and we demonstrate linear and shift invariance of the imaging system by imaging a resolution phantom and mice injected with Resovist.

Keywords

Magnetic Particle Point Spread Function NdFeB Magnet Mouse Image Shift Invariance 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Gleich, B., Weizenecker, J.: Tomographic imaging using the nonlinear response of magnetic particles. Nature 435, 1214–1217 (2005)CrossRefGoogle Scholar
  2. 2.
    Weizenecker, J., Gleich, B., Borgert, J.: Magnetic particle imaging using a field free line. Journal of Physics D: Applied Physics 41 (2008)Google Scholar
  3. 3.
    Knopp, T., Sattel, T.F., Biederer, S., Buzug, T.M.: Field-free line formation in a magnetic field. Journal of Physics A: Mathematical and Theoretical 43(1), 012002 (2010)CrossRefGoogle Scholar
  4. 4.
    Goodwill, P., Conolly, S.: The x-space formulation of the magnetic particle imaging process: 1-D signal, resolution, bandwidth, SNR, SAR, and magnetostimulation. IEEE Transactions on Medical Imaging 29, 1851–1859 (2010)CrossRefGoogle Scholar
  5. 5.
    Goodwill, P., Conolly, S.: Multidimensional x-space magnetic particle imaging. IEEE Transactions on Medical Imaging 30, 1581–1590 (2011)CrossRefGoogle Scholar
  6. 6.
    Goodwill, P., et al.: Ferrohydrodynamic relaxometry for magnetic particle imaging. Applied Physics Letters 98, 262502–262502-3 (2011)Google Scholar
  7. 7.
    Ferguson, R.M., Minard, K.R., Khandhar, A.P., Krishnan, K.M.: Optimizing magnetite nanoparticles for mass sensitivity in magnetic particle imaging. Medical Physics 38(3), 1619 (2011)CrossRefGoogle Scholar
  8. 8.
    Lu, K., Goodwill, P., Zheng, B., Conolly, S.: The impact of filtering direct-feedthrough on the x-space theory of magnetic particle imaging. In: Proceedings of SPIE, vol. 7965, p. 79852 (2011)Google Scholar

Copyright information

© Springer-Verlag GmbH Berlin Heidelberg 2012

Authors and Affiliations

  • Patrick Goodwill
    • 1
  • Justin Konkle
    • 1
  • Bo Zheng
    • 1
  • Steven Conolly
    • 1
  1. 1.Department of Bioengineering and EECSUC-BerkeleyBerkeleyUSA

Personalised recommendations