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Magnetic-Particle-Imaging for Sentinel Lymph Node Biopsy in Breast Cancer

  • Ksenija GräfeEmail author
  • Timo F. Sattel
  • Kerstin Lüdtke-Buzug
  • Dominique Finas
  • Jörn Borgert
  • Thorsten M. Buzug
Part of the Springer Proceedings in Physics book series (SPPHY, volume 140)

Abstract

Magnetic Particle Imaging (MPI) is a very recent medical imaging technique providing tomographic data avoiding use of ionizing radiation. The first MPI scanner presented by Gleich and Weizenecker has a closed geometry which has to fit the object of interest [1]. In order to be able to examine larger objects, Sattel et al. developed a new coil configuration, the single-sided MPI scanner geometry [2]. The detection of axillary sentinel lymph nodes is one medical application scenario. MPI improves the surgical procedure by real-time 3D image guidance and may contribute towards reducing cost and the time needs per patient. This contribution presents improvements of various coil topologies. Furthermore, the cooling system is optimized and the send and receive chain will be improved.

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References

  1. 1.
    Gleich, B., Weizenecker, J.: Tomographic imaging using the nonlinear response of magnetic particles. Nature 435, 1214–1217 (2005)CrossRefGoogle Scholar
  2. 2.
    Sattel, T., Knopp, T., Biederer, S., Gleich, B., Weizenecker, J., Borgert, J., Buzug, T.M.: Single-sided device for magnetic particle imaging. Journal of Physics D: Applied Physics 42(2), 1–5 (2009)CrossRefGoogle Scholar
  3. 3.
    Sattel, T.F., Biederer, S., Knopp, T., Buzug, T.M.: Magnetic Field Generation for Multi-Dimensional Single-Sided Magentic Particle Imaging. In: Proceedings of the Inetrnetional Society for Magnetic Resonance in Medicine, Mai, Stockholm,18, p. 3297 (2010)Google Scholar

Copyright information

© Springer-Verlag GmbH Berlin Heidelberg 2012

Authors and Affiliations

  • Ksenija Gräfe
    • 1
    Email author
  • Timo F. Sattel
    • 1
  • Kerstin Lüdtke-Buzug
    • 1
  • Dominique Finas
    • 2
  • Jörn Borgert
    • 3
  • Thorsten M. Buzug
    • 1
  1. 1.Institute of Medical EngineeringUniversity of LübeckLübeckGermany
  2. 2.Department of Obstetrics and GynacologyUniversity of LübeckLübeckGermany
  3. 3.Research LaboratoriesPhillips Technologie GmbH, Innovative TechnologiesHamburgGermany

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