Abstract
Magnetic particle imaging (MPI) is an emerging medical imaging modality capable of high-sensitivity images with unprecedented contrast and without ionizing radiation [1]. Our laboratory previously developed the x-space theory for MPI, which describes MPI as a scanning process in the spatial domain [2,3]. X-space MPI is particularly critical as it permits real-time image reconstruction, orders of magnitude faster than the traditional harmonic space system matrix reconstruction methods. The x-space theory was derived assuming adiabatic and instantaneous alignment of ultra-small superparamagnetic iron oxide nanoparticles (USPIOs) with the applied magnetic field. However, in reality the magnetization lags behind the applied field due to relaxation. Here, we include relaxation in the x-space MPI theory and show that real-time reconstruction is still feasible even with relaxation effects.
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References
Gleich, B., Weizenecker, J.: Tomographic imaging using the nonlinear response of magnetic particles. Nature 435, 1214–1217 (2005)
Goodwill, P., Conolly, S.: The x-space formulation of the magnetic particle imaging process: 1-D signal, resolution, bandwidth, SNR, SAR, and magnetostimulation. IEEE Transactions on Medical Imaging 29, 1851–1859 (2010)
Goodwill, P., Conolly, S.: Multidimensional x-space magnetic particle imaging. IEEE Transactions on Medical Imaging 30, 1581–1590 (2011)
Lu, M., et al.: FDA report: ferumoxytol for intravenous iron therapy in adult patients with chronic kidney disease. American Journal of Hematology 85, 315–319 (2010)
Debye, P.: Polar Molecules. The Chemical Catalog Company, New York (1929)
Shliomis, M.: Magnetic fluids. Sov. Phys.-Usp. 17, 153–169 (1974)
Lu, K., Goodwill, P., Zheng, B., Conolly, S.: The impact of filtering direct-feedthrough on the x-space theory of magnetic particle imaging. In: Proceedings of SPIE, vol. 7965, p. 79852I (2011)
Goodwill, P., et al.: Ferrohydrodynamic relaxometry for magnetic particle imaging. Applied Physics Letters 98, 262502–262502-3 (2011)
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© 2012 Springer-Verlag GmbH Berlin Heidelberg
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Croft, L.R., Goodwill, P., Ferguson, M., Krishnan, K., Conolly, S. (2012). Relaxation in x-space Magnetic Particle Imaging. In: Buzug, T., Borgert, J. (eds) Magnetic Particle Imaging. Springer Proceedings in Physics, vol 140. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-24133-8_24
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DOI: https://doi.org/10.1007/978-3-642-24133-8_24
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-24132-1
Online ISBN: 978-3-642-24133-8
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