Skip to main content

Relaxation in x-space Magnetic Particle Imaging

  • Conference paper

Part of the book series: Springer Proceedings in Physics ((SPPHY,volume 140))

Abstract

Magnetic particle imaging (MPI) is an emerging medical imaging modality capable of high-sensitivity images with unprecedented contrast and without ionizing radiation [1]. Our laboratory previously developed the x-space theory for MPI, which describes MPI as a scanning process in the spatial domain [2,3]. X-space MPI is particularly critical as it permits real-time image reconstruction, orders of magnitude faster than the traditional harmonic space system matrix reconstruction methods. The x-space theory was derived assuming adiabatic and instantaneous alignment of ultra-small superparamagnetic iron oxide nanoparticles (USPIOs) with the applied magnetic field. However, in reality the magnetization lags behind the applied field due to relaxation. Here, we include relaxation in the x-space MPI theory and show that real-time reconstruction is still feasible even with relaxation effects.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD   219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Gleich, B., Weizenecker, J.: Tomographic imaging using the nonlinear response of magnetic particles. Nature 435, 1214–1217 (2005)

    Article  Google Scholar 

  2. Goodwill, P., Conolly, S.: The x-space formulation of the magnetic particle imaging process: 1-D signal, resolution, bandwidth, SNR, SAR, and magnetostimulation. IEEE Transactions on Medical Imaging 29, 1851–1859 (2010)

    Article  Google Scholar 

  3. Goodwill, P., Conolly, S.: Multidimensional x-space magnetic particle imaging. IEEE Transactions on Medical Imaging 30, 1581–1590 (2011)

    Article  Google Scholar 

  4. Lu, M., et al.: FDA report: ferumoxytol for intravenous iron therapy in adult patients with chronic kidney disease. American Journal of Hematology 85, 315–319 (2010)

    Google Scholar 

  5. Debye, P.: Polar Molecules. The Chemical Catalog Company, New York (1929)

    MATH  Google Scholar 

  6. Shliomis, M.: Magnetic fluids. Sov. Phys.-Usp. 17, 153–169 (1974)

    Article  Google Scholar 

  7. Lu, K., Goodwill, P., Zheng, B., Conolly, S.: The impact of filtering direct-feedthrough on the x-space theory of magnetic particle imaging. In: Proceedings of SPIE, vol. 7965, p. 79852I (2011)

    Google Scholar 

  8. Goodwill, P., et al.: Ferrohydrodynamic relaxometry for magnetic particle imaging. Applied Physics Letters 98, 262502–262502-3 (2011)

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Laura R. Croft .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2012 Springer-Verlag GmbH Berlin Heidelberg

About this paper

Cite this paper

Croft, L.R., Goodwill, P., Ferguson, M., Krishnan, K., Conolly, S. (2012). Relaxation in x-space Magnetic Particle Imaging. In: Buzug, T., Borgert, J. (eds) Magnetic Particle Imaging. Springer Proceedings in Physics, vol 140. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-24133-8_24

Download citation

Publish with us

Policies and ethics