The Potential of Magnetic Particle Imaging in the Competitive Environment of Cardiac Diagnostics

  • Gunnar Schütz
Part of the Springer Proceedings in Physics book series (SPPHY, volume 140)


Magnetic particle imaging (MPI) is a novel real-time imaging technique visualizing magnetic nanoparticles. Due to its intrinsic features it is especially suited for functional cardiac diagnosis, including angiography, cardiac wall motion assessment and quantitative myocardial perfusion imaging. In addition it may be suitable for cardiac intervention. MPI may reduce the overall diagnostic procedure duration and the complexity of recommended diagnostic pathways, thereby providing medical benefits to patients and economical benefits to hospitals / cardiologists due to the expected increased patient throughput.


Percutaneous Coronary Intervention Myocardial Perfusion Imaging Stable Angina Invasive Coronary Angiography Diagnostic Pathway 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Gleich, B., Weizenecker, J.: Tomographic imaging using the nonlinear response of magnetic particles. Nature 435(7046), 1214–1217 (2005)CrossRefGoogle Scholar
  2. 2.
    Walker, R., et al.: Chest pain of recent onset: Assessment and diagnosis of recent onset chest pain or discomfort of suspected cardiac origin. National Institute for Health and Clinical Excellence (2003)Google Scholar
  3. 3.
    Dangas, G., et al.: Vascular complications after percutaneous coronary interventions following hemostasis with manual compression versus arteriotomy closure devices. J. Am. Coll. Cardiol. 38(3), 638–641 (2001)CrossRefGoogle Scholar
  4. 4.
    Bruckenberger, E.: Herzbericht 2010, vol. 23, p. 56 (2010)Google Scholar
  5. 5.
    Iida, H., Eberl, S.: Quantitative assessment of regional myocardial blood flow with thallium-201 and SPECT. J. Nucl. Cardiol. 5(3), 313–331 (1998)CrossRefGoogle Scholar
  6. 6.
    Di Carli, M.F., et al.: Clinical myocardial perfusion PET/CT. J. Nucl. Med. 48(5), 783–793 (2007)CrossRefGoogle Scholar
  7. 7.
    Bamberg, F., et al.: Dynamic myocardial stress perfusion imaging using fast dual-source CT with alternating table positions: initial experience. Eur. Radiol. 20(5), 1168–1173 (2010)MathSciNetCrossRefGoogle Scholar
  8. 8.
    Porter, T.R., Xie, F.: Myocardial perfusion imaging with contrast ultrasound. JACC Cardiovasc. Imaging 3(2), 176–187 (2010)CrossRefGoogle Scholar
  9. 9.
    Bluemke, D.A., et al.: Noninvasive coronary artery imaging: magnetic resonance angiography and multidetector computed tomography angiography: a scientific statement from the american heart association committee on cardiovascular imaging and intervention of the council on cardiovascular radiology and intervention, and the councils on clinical cardiology and cardiovascular disease in the young. Circulation 118(5), 586–606 (2008)CrossRefGoogle Scholar
  10. 10.
    Breton, E., et al.: Quantitative contrast-enhanced first-pass cardiac perfusion MRI at 3 tesla with accurate arterial input function and myocardial wall enhancement. J. Magn. Reson. Imaging (2011)Google Scholar
  11. 11.
    Serruys, P.W., et al.: Percutaneous coronary intervention versus coronary-artery bypass grafting for severe coronary artery disease. N. Engl. J. Med. 360(10), 961–972 (2009)CrossRefGoogle Scholar
  12. 12.
    Sattel, T.F., et al.: Single-sided device for magnetic particle imaging. Journal of Physics D: Applied Physics 42(2) (2009)Google Scholar

Copyright information

© Springer-Verlag GmbH Berlin Heidelberg 2012

Authors and Affiliations

  1. 1.MR & CT Contrast Media ResearchBayer Pharma AGBerlinGermany

Personalised recommendations