Abstract
The use of magnetic nanoparticles as contrast agents in biomedical applications requires highly reproducible markers soluble in aqueous media. Here we present a modular approach for the formation of a magnetic contrast agent, which is composed of an inorganic core like iron oxide and a water solubility mediating polymer shell. The shell can also be a carrier for specific affinity molecules like antibodies or peptides, which offer the possibility to selectively target surface receptors upon cells.
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© 2012 Springer-Verlag GmbH Berlin Heidelberg
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Niehaus, J., Becker, S., Schmidtke, C., Werner, K., Weller, H. (2012). Precision Synthesis of Iron Oxide Nanoparticles and Their Use as Contrast Agents. In: Buzug, T., Borgert, J. (eds) Magnetic Particle Imaging. Springer Proceedings in Physics, vol 140. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-24133-8_14
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DOI: https://doi.org/10.1007/978-3-642-24133-8_14
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-24132-1
Online ISBN: 978-3-642-24133-8
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