Part of the Use R! book series (USE R)
Estimation Under Order Restrictions
Chapter 2 covers the basic setting on which we focus in the first part of this book, i.e., the one in which a response variable Y is expected to increase or decrease monotonically with respect to increasing levels of a predictor variable x which in biomedical applications is usually the dose or concentration of a drug. We assume that the mean response is given by
where μ( ) is an unknown monotone function. In Chap. 2, we focus on the estimation problem under order restriction using isotonic regression.
$$E(Y \vert x) = \mu (x),$$
KeywordsMaximum Likelihood Estimate Design Point Final Number Order Restriction Graphical Interpretation
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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