Assembly and Fragmentation of Tat Pores

  • Ksenia Guseva
Part of the Springer Theses book series (Springer Theses)


In this chapter we determine how the formation of transient pores on the membrane depends on the dynamics of its assembly process. We analyse the temporary pores formed by the Tat translocation system, which is responsible for protein transport through the membrane. Its main mechanism is the polymerisation of its subunits, in response to a signal of demand of the transport from a protein in the cell cytoplasm. The direct correlation of the size of the assembled pore and the size of the protein determines the speed of the translocation process. Using a differential equation approach we obtain that the flux of a given protein depends quadratically on its size.


Export Rate Subunit Assembly Free Monomer Translocation System Twin Arginine Translocation 
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Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  1. 1.Department of Physics, Institute of Complex Systems and Mathematical BiologyUniversity of AberdeenAberdeenUK

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