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Localized Component Analysis for Arthritis Detection in the Trapeziometacarpal Joint

  • Martijn van de Giessen
  • Sepp de Raedt
  • Maiken Stilling
  • Torben B. Hansen
  • Mario Maas
  • Geert J. Streekstra
  • Lucas J. van Vliet
  • Frans M. Vos
Part of the Lecture Notes in Computer Science book series (LNCS, volume 6892)

Abstract

The trapeziometacarpal joint enables the prehensile function of the thumb. Unfortunately, this joint is vulnerable to osteoarthritis (OA) that typically affects the local shape of the trapezium. A novel, local statistical shape model is defined that employs a differentiable locality measure based on the weighted variance of point coordinates per mode. The simplicity of the function and the smooth derivative enable to quickly determine localized components for densely sampled surfaces.

The method is employed to assess a set of 60 trapezia (38 healthy, 22 with OA). The localized components predominantly model regions affected by OA, contrary to shape variations found with PCA. Furthermore, identification of pathological trapezia based on the localized modes of variation is improved compared to PCA.

Keywords

Surface Point Localize Component Statistical Shape Model Receiver Operating Curf Point Distribution Model 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2011

Authors and Affiliations

  • Martijn van de Giessen
    • 1
    • 2
    • 5
  • Sepp de Raedt
    • 1
  • Maiken Stilling
    • 3
  • Torben B. Hansen
    • 3
  • Mario Maas
    • 4
  • Geert J. Streekstra
    • 5
  • Lucas J. van Vliet
    • 1
  • Frans M. Vos
    • 1
    • 4
  1. 1.Quantititative Imaging GroupDelft University of TechnologyThe Netherlands
  2. 2.Division of Image ProcessingLeiden University Medical CenterThe Netherlands
  3. 3.Dept. of OrthopaedicsHolstebro Regional HospitalDenmark
  4. 4.Dept. of RadiologyAMCAmsterdamThe Netherlands
  5. 5.Dept. of Biomed. Engineering and PhysicsAMCAmsterdamThe Netherlands

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