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Bessel Fourier Orientation Reconstruction: An Analytical EAP Reconstruction Using Multiple Shell Acquisitions in Diffusion MRI

  • Ameer Pasha Hosseinbor
  • Moo K. Chung
  • Yu-Chien Wu
  • Andrew L. Alexander
Part of the Lecture Notes in Computer Science book series (LNCS, volume 6892)

Abstract

The estimation of the ensemble average propagator (EAP) directly from q-space DWI signals is an open problem in diffusion MRI. Diffusion spectrum imaging (DSI) is one common technique to compute the EAP directly from the diffusion signal, but it is burdened by the large sampling required. Recently, several analytical EAP reconstruction schemes for multiple q-shell acquisitions have been proposed. One, in particular, is Diffusion Propagator Imaging (DPI) which is based on the Laplace’s equation estimation of diffusion signal for each shell acquisition. Viewed intuitively in terms of the heat equation, the DPI solution is obtained when the heat distribution between temperatuere measurements at each shell is at steady state.

We propose a generalized extension of DPI, Bessel Fourier Orientation Reconstruction (BFOR), whose solution is based on heat equation estimation of the diffusion signal for each shell acquisition. That is, the heat distribution between shell measurements is no longer at steady state. In addition to being analytical, the BFOR solution also includes an intrinsic exponential smootheing term. We illustrate the effectiveness of the proposed method by showing results on both synthetic and real MR datasets.

Keywords

Heat Equation Diffusion Spectrum Imaging Spherical Harmonic Basis White Matter Voxels Harmonic Oscillator Problem 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2011

Authors and Affiliations

  • Ameer Pasha Hosseinbor
    • 1
  • Moo K. Chung
    • 1
  • Yu-Chien Wu
    • 1
  • Andrew L. Alexander
    • 1
  1. 1.University of Wisconsin-MadisonMadisonUSA

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