Abstract
Ground glass nodules (GGNs) occur less frequent in computed tomography (CT) scans than solid nodules but have a much higher chance of being malignant. Accurate detection of these nodules is therefore highly important. A complete system for computer-aided detection of GGNs is presented consisting of initial segmentation steps, candidate detection, feature extraction and a two-stage classification process. A rich set of intensity, shape and context features is constructed to describe the appearance of GGN candidates. We apply a two-stage classification approach using a linear discriminant classifier and a GentleBoost classifier to efficiently classify candidate regions. The system is trained and independently tested on 140 scans that contained one or more GGNs from around 10,000 scans obtained in a lung cancer screening trial. The system shows a high sensitivity of 73% at only one false positive per scan.
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Jacobs, C., Sánchez, C.I., Saur, S.C., Twellmann, T., de Jong, P.A., van Ginneken, B. (2011). Computer-Aided Detection of Ground Glass Nodules in Thoracic CT Images Using Shape, Intensity and Context Features. In: Fichtinger, G., Martel, A., Peters, T. (eds) Medical Image Computing and Computer-Assisted Intervention – MICCAI 2011. MICCAI 2011. Lecture Notes in Computer Science, vol 6893. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-23626-6_26
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DOI: https://doi.org/10.1007/978-3-642-23626-6_26
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