Robust and Stable Small-World Topology of Brain Intrinsic Organization during Pre- and Post-Task Resting States

  • Zhijiang Wang
  • Jiming Liu
  • Ning Zhong
  • Yulin Qin
  • Haiyan Zhou
  • Kuncheng Li
Part of the Lecture Notes in Computer Science book series (LNCS, volume 6889)


Brain functional network studies have demonstrated the small-world topology as the nature of large-scale spontaneous brain activity. Studies have also revealed that the temporal coherence of spontaneous activity could be reshaped during task-dependent (or post-task) resting states within local spatial patterns such as task-related and the default-mode networks. However, to our best knowledge, it is still a lack of rigorous investigations that whether the small-world topology of spontaneous intrinsic organization remains robust and stable during different resting states. To address the problem, we recorded blood oxygen level-dependent (BOLD) signals from two rests (namely, pre- and post-task resting states) before and after a simple semantic-matching task, and investigated the preceding task influences on the topology of the large-scale spontaneous intrinsic organization during the post-task resting state. The major findings are that the small-world configuration of spontaneous intrinsic organization remains robust and stable during resting states regardless of preceding task influences.


Functional Connectivity Temporal Coherence Characteristic Path Length Preceding Task Brain Functional Network 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2011

Authors and Affiliations

  • Zhijiang Wang
    • 1
    • 2
  • Jiming Liu
    • 1
    • 2
    • 3
  • Ning Zhong
    • 1
    • 2
    • 4
  • Yulin Qin
    • 1
    • 2
    • 5
  • Haiyan Zhou
    • 1
    • 2
  • Kuncheng Li
    • 6
    • 2
  1. 1.International WIC InstituteBeijing University of TechnologyChina
  2. 2.Beijing Municipal Lab of Brain InformaticsChina
  3. 3.Dept. of Computer ScienceHong Kong Baptist UniversityChina
  4. 4.Dept. of Life Science and InformaticsMaebashi Institute of TechnologyJapan
  5. 5.Dept. of PsychologyCarnegie Mellon UniversityUSA
  6. 6.Dept. of RadiologyXuanwu Hospital, Capital Medical UniversityChina

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