Abstract
The history of parathyroid reoperation is as long as the history of parathyroid surgery. The first patient operated for hyperparathyroidism (HPT), the Vienese tram conductor Albert Jahne operated by Felix Mandl in 1925, initially experienced the benefit of successful removal of a parathyroid tumor. However, Jahne subsequently developed recurrent disease, possibly due to parathyroid carcinoma, was reoperated in 1932, without finding, and died from renal failure soon after the second exploration. Captain Charles Martell had persistent HPT with severe osteitis fibrosa cystica after six previous operations, including total thyroidectomy and excision of two normal-sized parathyroids, until Oliver Cope, at the Massachusetts General Hospital, in 1936 at the seventh operation found a mediastinal parathyroid adenoma (3 cm large). Martell had insisted on a mediastinal exploration after reading about the variable parathyroid anatomy. The hypercalcemia was reversed, but despite autotransplantation of part of the adenoma to muscle, the patient experienced severe hypocalcemia and died from tetany and sepsis 6 weeks later, after an operation for an impacted ureter stone.
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Åkerström, G., Stålberg, P., Hessman, O. (2012). Remedial Parathyroid Surgery. In: Oertli, D., Udelsman, R. (eds) Surgery of the Thyroid and Parathyroid Glands. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-23459-0_39
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