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Imaging and Imaging-Guided Intervention of the Parathyroid Glands

  • Georg M. Bongartz
  • Augustinus L. Jacob
  • Sebastian Kos
  • Egbert U. Nitzsche
  • Mehmet Ö. Öksüz
Chapter

Abstract

Primary hyperparathyroidism (HPTH) is often diagnosed accidentally as asymptomatic disease, when hypercalcemia and elevated PTH level are observed based upon a laboratory test. However, if a more vigorous patient’s history is taken, non-specific symptoms such as tiredness and irritation are frequently observed. In the majority of patients presenting with HPTH, cortical bone density is reduced, especially if measured at the distal radius. In about 80% of patients, a benign solitary parathyroid adenoma (PA) represents the cause of disease. Fourteen percent of patients present with multiple adenomas, in 5% hereditary forms of HPTH appear causative. In about 1% of cases, a parathyroid carcinoma is finally diagnosed.

Today, surgical therapy is recommended for all symptomatic patients with HPTH. Moreover, it must be emphasized that the results of several studies indicate that surgery may subsequently improve cortical bone density and the quality of life in such patients even in cases with mild HPTH [1]. Regarding surgery, minimal invasive parathyroidectomy represents the therapy of choice in the majority of patients.

Keywords

Thyroid Nodule Parathyroid Gland Superior Vena Cava Parathyroid Adenoma Parathyroid Carcinoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • Georg M. Bongartz
    • 1
  • Augustinus L. Jacob
    • 2
  • Sebastian Kos
    • 2
  • Egbert U. Nitzsche
    • 3
  • Mehmet Ö. Öksüz
    • 4
  1. 1.Department of Radiology and Nuclear MedicineUniversity Hospital BaselBaselSwitzerland
  2. 2.Division of Interventional Radiology, Department of Radiology and Nuclear MedicineUniversity Hospital BaselBaselSwitzerland
  3. 3.Department of Nuclear Medicine and PET CenterCantonal Hospital AarauAarauSwitzerland
  4. 4.Department of Radiology and Nuclear MedicineUniversity Hospital BaselBaselSwitzerland

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