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Anaplastic Thyroid Carcinoma

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Surgery of the Thyroid and Parathyroid Glands

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Abstract

Undifferentiated (anaplastic) thyroid carcinoma (ATC) is a highly malignant tumor that histologically appears wholly or partially composed of undifferentiated cells that exhibit immunohistochemical or ultrastructural features indicative of epithelial differentiation.

In older literature, synonyms such as “spindle and giant cell carcinoma,” “sarcomatoid carcinoma,” “pleomorphic carcinoma,” “dedifferentiated carcinoma,” “metaplastic carcinoma,” or “carcinosarcoma” are used to describe this very aggressive and lethal tumor, leading to death within a few months in most of the patients.

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Authors and Affiliations

  1. Department of Surgery, Division of General Surgery, Endocrine Surgery, Medical University of Vienna, Währinger Gürtel 18-20, A-1090, Vienna, Austria

    Reza Asari M.D., Christian Scheuba M.D. & Bruno Niederle M.D.

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  1. Reza Asari M.D.
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  2. Christian Scheuba M.D.
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  3. Bruno Niederle M.D.
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Correspondence to Reza Asari M.D. .

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Editors and Affiliations

  1. Chairman, Department of Surgery, University Hospital Basel, Spitalstr. 21, Basel, 4031, Switzerland

    Daniel Oertli

  2. Yale-New Haven Hospital, Department of Surgery, Yale University School of Medicine, Cedar Street 330FMB 102, New Haven, CT, 06520-8062, USA

    Robert Udelsman

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Asari, R., Scheuba, C., Niederle, B. (2012). Anaplastic Thyroid Carcinoma. In: Oertli, D., Udelsman, R. (eds) Surgery of the Thyroid and Parathyroid Glands. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-23459-0_19

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