Surgery for Solitary Thyroid Nodule Including Differentiated Thyroid Cancer

  • Leslie S. Wu
  • Sanziana Roman


Thyroid nodules are common in the United States, with a prevalence of 4–7% for palpable nodules. However, nonpalpable nodules discovered incidentally on ultrasound or at autopsy suggest an overall prevalence of 19–67%. The incidence of thyroid cancer has increased from 3.6 per 100,000 in 1973 to 8.7 per 100,000 in 2002—a 2.4-fold increase—with 87% of the increase due to the diagnosis of small differentiated thyroid cancers. The association between increasing age and incidence of thyroid nodules makes their diagnosis and treatment an important public health issue.

The majority of thyroid nodules are benign. Colloid nodules, cysts, and thyroiditis account for approximately 80%, and benign follicular and Hürthle cell adenomas account for 10–15% of all thyroid nodules. Overall, only 5% of thyroid nodules are malignant. The challenge for a clinician is to distinguish patients with malignancy, who are treated surgically, from patients with benign disease, who often are followed clinically.


Thyroid Cancer Papillary Thyroid Carcinoma Thyroid Nodule Total Thyroidectomy Papillary Thyroid Cancer 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  1. 1.Department of SurgeryMaine Medical CenterPortlandUSA
  2. 2.Department of SurgeryYale University School of MedicineNew HavenUSA

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