Pharmacotechnical Assessment of Processed Watermelon Flesh as Novel Tablet Disintegrant

  • S. Pushkar
  • Nikhil K. Sachan
  • S. K. Ghosh


The biomaterial from hydro-extracted aqua soluble fraction of Citrullus lanatus was characterized and evaluated for its possible use as novel disintegrating agent in the formulation of solid dosage forms. The product was valuated as excipient for repose angle, bulk density, tapped density, water activity, particle size distribution, sorption behavior, compressibility, color, pH of the solution and excipient qualification parameters as per the guidelines of ‘International Pharmaceutical Excipient Council’. This investigation revealed the hydro-extracted watermelon flesh powder as a promising new excipient material for pharmaceutical usage.


Water Activity Fruit Pulp Solid Dosage Form Pharmaceutical Excipient Compressibility Index 
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Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • S. Pushkar
    • 1
  • Nikhil K. Sachan
    • 1
  • S. K. Ghosh
    • 2
  1. 1.University Institute of PharmacyC. S. J. M. UniversityKanpurIndia
  2. 2.Department of Pharmaceutical SciencesDibrugarh UniversityDibrugarhIndia

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