Experimental Evidence of a Role for RLKs in Innate Immunity

  • Thomas BollerEmail author
Part of the Signaling and Communication in Plants book series (SIGCOMM, volume 13)


Four lines of experimental evidence point to a major role of RLKs in plant innate immunity. First, several RLKs are located at the plasma membrane and perceive specific “microbe-associated molecular patterns” (MAMPs), such as bacterial flagellin, bacterial EF-Tu or fungal chitin. The high affinity and specificity of these RLKs for their respective ligands, and the absence of endogenous ligands in plants, strongly indicate that these RLKs serve as “pattern recognition receptors” (PRRs) to signal the presence of microbes. Second, mutational loss of individual PRRs can lead to a reduced resistance against pathogens. Third, biotechnological transfer of a PRR from one given plant species to another may lead to increased resistance against pathogens. Fourth, and most importantly, successful pathogens produce effectors that inhibit the PRRs themselves or prevent the signal transduction pathways activated upon stimulation of the PRRs.


Perception System Avirulence Gene Innate Immunity Receptor Induce Defense Response Nanomolar Level 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  1. 1.Zürich-Basel Plant Science Center, Botanical InstituteUniversity BaselBaselSwitzerland

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