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46,XY DSD

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Disorders of Sex Development

Abstract

46,XY DSD comprise a very heterogeneous group of conditions where the male hormones are not produced in sufficient quantities or the target organs are unable to respond. The most commonly diagnosed conditions are androgen insensitivity syndrome (AIS) – partial or complete, and defects in androgen synthesis. Many 46,XY DSD, however, are not yet able to be diagnosed at a molecular level, and much current research is directed to trying to resolve this dilemma, to improve treatment options.

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  1. Department of Endocrinology and Diabetes, Royal Children’s Hospital Melbourne, Parkville, VIC, Australia

    Jacqueline K. Hewitt & Garry L. Warne

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  1. Jacqueline K. Hewitt
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  2. Garry L. Warne
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Correspondence to Jacqueline K. Hewitt .

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  1. , Department of Urology, The Royal Children's Hospital, Flemington Road, Parkville, 3052, Victoria, Australia

    John M. Hutson

  2. , Department of Endocrinology and Diabetes, The Royal Children's Hospital, Flemington Road, Parkville, 3052, Victoria, Australia

    Garry L. Warne

  3. , Department of Gynaecology, Royal Children's Hospital, Flemington Road, Parkville, 3052, Victoria, Australia

    Sonia R. Grover

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Hewitt, J.K., Warne, G.L. (2012). 46,XY DSD. In: Hutson, J., Warne, G., Grover, S. (eds) Disorders of Sex Development. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-22964-0_7

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