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Morphology and Location of Electrophysiologically Identified Sensory Airway Receptors

  • Inge BrounsEmail author
  • Isabel Pintelon
  • Jean-Pierre Timmermans
  • Dirk Adriaensen
Chapter
Part of the Advances in Anatomy, Embryology and Cell Biology book series (ADVSANAT, volume 211)

Abstract

Technical and methodological limitations prevent direct measurements and manipulation of individual intrapulmonary sensory airway receptors, forcing lung physiologists to make indirect interpretations of the events that occur at the level of the (sensory) receptor endings. Recent reviews described at least six subtypes of vagal sensory airway receptors, including SARs, RARs, bronchial and pulmonary CFRs, HTARs and cough receptors (Widdicombe 2009). Knowledge of the characteristics of intrapulmonary sensory receptor morphology is, however, crucial because the behaviour of sensory units largely depends on it. To allow for reproducible location and morphological identification of the distinct populations of electrophysiologically identified airway receptors, the neurochemical characteristics of afferent nerve terminals need to be determined, and likely will turn out to be essential to (finally) define the actual targets of the many subpopulations of airway-related vagal afferents (Yu 2009).

Keywords

Airway Smooth Muscle Afferent Nerve Terminal Complex Terminal Smooth Muscle Bundle Neurochemical Characteristic 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • Inge Brouns
    • 1
    Email author
  • Isabel Pintelon
    • 1
  • Jean-Pierre Timmermans
    • 2
  • Dirk Adriaensen
    • 2
  1. 1.Department of Veterinary Sciences Laboratory of Cell Biology and HistologyUniversity of AntwerpAntwerpBelgium
  2. 2.Department of Veterinary Sciences Laboratory of Cell Biology and HistologyUniversity of AntwerpAntwerpenBelgium

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