Abstract
This paper verifies the robustness of a model based predictive control scheme for depth of anesthesia (DOA) regulation. The manipulated variable is Propofol, which is used in a Model based Predictive Control (MPC) algorithm for automatic induction and control of DOA. In turn, DOA is evaluated by means of the Bispectral index (BIS). The simulation tests are performed on a set of 17 virtually generated realistic patients with significantly varying sensitivity to Propofol infusion. The results show a high-efficiency, optimal dosage and robustness of the MPC algorithm to induce and maintain the desired BIS reference while rejecting typical disturbances from surgery.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2011 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Ionescu, C.M., Nascu, I., De Keyser, R. (2011). Robustness Tests of a Model Based Predictive Control Strategy for Depth of Anesthesia Regulation in a Propofol to Bispectral Index Framework. In: Vlad, S., Ciupa, R.V. (eds) International Conference on Advancements of Medicine and Health Care through Technology. IFMBE Proceedings, vol 36. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-22586-4_50
Download citation
DOI: https://doi.org/10.1007/978-3-642-22586-4_50
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-22585-7
Online ISBN: 978-3-642-22586-4
eBook Packages: EngineeringEngineering (R0)