Clinical Manifestations of Choroidal Neovascularization in AMD
Choroidal neovascularization (CNV) presents with a variety of visual symptoms and signs that can serve as clues to the proper diagnosis [1–3]. The physical invasion of blood vessels and associated cellular infiltrate distorts retinal tissue. Associated leakage, bleeding, and eventual scarring can have profound effects on macular function. Recognition of the presence of CNV is fairly easy in advanced cases, but by then, there often is severe vision loss. CNV secondary to age-related macular degeneration (AMD) used to be the leading cause of legal blindness among older adults . With modern treatments aimed against vascular endothelial growth factor (VEGF), the visual acuity in a large majority of patients can be stabilized over the long term, but visual acuity improvement occurs in a minority of patients [5, 6]. Therefore, early diagnosis, prior to the patient suffering severe loss of vision, is the best hope of maintaining visual function in these older adults.
KeywordsOptical Coherence Tomography Fluorescein Angiography Cystoid Macular Edema Polypoidal Choroidal Vasculopathy Subretinal Fluid
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