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Clinical Manifestations of Choroidal Neovascularization in AMD

  • R. F. SpaideEmail author
Chapter

Abstract

Choroidal neovascularization (CNV) presents with a variety of visual symptoms and signs that can serve as clues to the proper diagnosis [1–3]. The physical invasion of blood vessels and associated cellular infiltrate distorts retinal tissue. Associated leakage, bleeding, and eventual scarring can have profound effects on macular function. Recognition of the presence of CNV is fairly easy in advanced cases, but by then, there often is severe vision loss. CNV secondary to age-related macular degeneration (AMD) used to be the leading cause of legal blindness among older adults [4]. With modern treatments aimed against vascular endothelial growth factor (VEGF), the visual acuity in a large majority of patients can be stabilized over the long term, but visual acuity improvement occurs in a minority of patients [5, 6]. Therefore, early diagnosis, prior to the patient suffering severe loss of vision, is the best hope of maintaining visual function in these older adults.

Keywords

Optical Coherence Tomography Fluorescein Angiography Cystoid Macular Edema Polypoidal Choroidal Vasculopathy Subretinal Fluid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  1. 1.Vitreous-Retina-Macula Consultants of New YorkManhattan Eye, Ear, and Throat HospitalNew YorkUSA

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