Surgical Therapy

  • B. KirchhofEmail author


The term “maculoplasty” is a future vision.So far, “surgical therapy” stands for the autologous replacement of affected retinal pigment epithelium by a hybrid of functioning retinal pigment epithelium and choroid.


Retinal Pigment Epithelium Pigment Epithelium Subretinal Space Secondary Bleeding Macular Dystrophy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. 1.
    del Priore LV, Tezel TH, Kaplan HJ (2006) Maculoplasty for age-related macular degeneration: reengineering Bruch’s membrane and the human macula. Prog Retin Eye Res 25:539–562PubMedCrossRefGoogle Scholar
  2. 2.
    Schrader WF (2006) Age-related macular degeneration: a socioeconomic time bomb in our aging society. Ophthalmologe 103:742–748PubMedCrossRefGoogle Scholar
  3. 3.
    Maclaren RE, Pearson RA, Macneil A et al (2006) Retinal repair by transplantation of photoreceptor precursors. Nature 444:203–207PubMedCrossRefGoogle Scholar
  4. 4.
    Bressler NM, Bressler SB, Hawkins BS, Marsh MJ, Sternberg P Jr, Thomas MA (2000) Submacular surgery trials randomized pilot trial of laser photocoagulation versus surgery for recurrent choroidal neovascularization secondary to age-related macular degeneration: I. Ophthalmic outcomes submacular surgery trials pilot study report number 1. Am J Ophthalmol 130:387–407PubMedCrossRefGoogle Scholar
  5. 5.
    Kirchhof B (2009) Full macular translocation in exsudative age related macular degeneration. doi: 10.3207/0663207832. 14 Aug 2009
  6. 6.
    Machemer R (1998) Macular translocation. Am J Ophthalmol 125:698–700PubMedCrossRefGoogle Scholar
  7. 7.
    Cahill MT, Freedman SF, Toth CA (2003) Macular translocation with 360 degrees peripheral retinectomy for geographic atrophy. Arch Ophthalmol 121:132–133PubMedCrossRefGoogle Scholar
  8. 8.
    Lappas A, Foerster AM, Weinberger AW, Coburger S, Schrage NF, Kirchhof B (2004) Translocation of iris pigment epithelium in patients with exudative age-related macular degeneration: long-term results. Graefes Arch Clin Exp Ophthalmol 242:638–647PubMedCrossRefGoogle Scholar
  9. 9.
    van Meurs JC, Ter AE, Hofland LJ et al (2004) Autologous peripheral retinal pigment epithelium translocation in patients with subfoveal neovascular membranes. Br J Ophthalmol 88:110–113PubMedCrossRefGoogle Scholar
  10. 10.
    Cereda MG, Parolini B, Bellesini E, Pertile G (2010) Surgery for CNV and autologous choroidal RPE patch transplantation: exposing the submacular space. Graefes Arch Clin Exp Ophthalmol 248:37–47PubMedCrossRefGoogle Scholar
  11. 11.
    Kirchhof B (2009) RPE and choroid translocation in anti-VEGF-non-responder. doi: 10.3207/0274288554. 24 July 2009
  12. 12.
    Heimes B, Lommatzsch A, Zeimer M, Gutfleisch M, Spital G, Dietzel M, Pauleikhoff D (2011) Long-term visual course after anti-VEGF therapy for exudative AMD in clinical practice evaluation of the German reinjection scheme. Graefes Arch Clin Exp Ophthalmol 249:639–644Google Scholar
  13. 13.
    Gerding H, Loukopoulos V, Riese J, Hefner L, Timmermann M (2011) Results of flexible ranibizumab treatment in age-related macular degeneration and search for parameters with impact on outcome. Graefes Arch Clin Exp Ophthalmol 249:653–662Google Scholar
  14. 14.
    Heussen FM, Fawzy NF, Joeres S et al (2008) Autologous translocation of the choroid and RPE in age-related macular degeneration: 1-year follow-up in 30 patients and recommendations for patient selection. Eye (Lond) 22:799–807CrossRefGoogle Scholar
  15. 15.
    Kuhli-Hattenbach C, Fischer IB, Schalnus R, Hattenbach LO (2010) Subretinal hemorrhages associated with age-related macular degeneration in patients receiving anticoagulation or antiplatelet therapy. Am J Ophthalmol 149:316–321PubMedCrossRefGoogle Scholar
  16. 16.
    Chen CY, Hooper C, Chiu D, Chamberlain M, Karia N, Heriot WJ (2007) Management of submacular hemorrhage with intravitreal injection of tissue plasminogen activator and expansile gas. Retina 27:321–328PubMedCrossRefGoogle Scholar
  17. 17.
    Kirchhof B (2009) RPE and choroid translocation in geographic atrophy. doi: 10.3207/2833590479. 4 July 2009
  18. 18.
    Caramoy A, Liakopoulos S, Menrath E, Kirchhof B (2010) Autologous translocation of choroid and retinal pigment epithelium in geographic atrophy: long-term functional and anatomical outcome. Br J Ophthalmol 94(8):1040–1044PubMedCrossRefGoogle Scholar
  19. 19.
    Chen FK, Uppal GS, Rubin GS, Webster AR, Coffey PJ, Da CL (2008) Evidence of retinal function using microperimetry following autologous retinal pigment epithelium-choroid graft in macular dystrophy. Invest Ophthalmol Vis Sci 49:3143–3150PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  1. 1.Department of OphthalmologyUniversity of CologneCologneGermany

Personalised recommendations