Skip to main content

Analgetika

  • Chapter

Zusammenfassung

Für die Schmerzbehandlung werden in erster Linie Opioide und nichtopioide Analgetika eingesetzt. Die nichtopioiden Analgetika wirken zusätzlich antipyretisch, einige auch entzündungshemmend. In manchen Fällen bereitet es Schwierigkeiten, eine eindeutige Trennung von Analgetika gegenüber den Antirheumatika und Antiphlogistika vorzunehmen. So wird Acetylsalicylsäure besonders in Deutschland vorzugsweise zur Behandlung von Schmerzen eingesetzt. Sie wirkt aber in höheren Dosen auch antiphlogistisch. Seit mehreren Jahren werden die nichtsteroidalen Antiphlogistika Ibuprofen, Naproxen und Diclofenac in geringerer Dosis als rezeptfreie Schmerzmittel verwendet.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   59.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  • Allan L, Richarz U, Simpson K, Slappendel R (2005): Transdermal fentanyl versus sustained release oral morphine in strong-opioid naive patients with chronic low back pain. Spine 30: 2484–2490.

    Article  PubMed  Google Scholar 

  • Arzneimittelkommission der deutschen Ärzteschaft (1986): Bundesgesundheitsamt schrankt Anwendungsgebiet von Metamizol-haltigen Monopraparaten ein. Dtsch Ärztebl 83: 3267.

    Google Scholar 

  • Arzneimittelkommission der deutschen Ärzteschaft (2007): Empfehlungen zur Therapie von Tumorschmerzen. AVP-Sonderheft Therapieempfehlungen, 3. Auflage. Internet: www.akdae.de/35/10/66-Tumorschmerzen-2007-3Auflage.pdf

  • Budd K (1990): Experience with partial antagonists in the treatment of cancer pain. In: Doyle D (Ed). Opioids in the treatment of cancer pain. Royal Society of Medicine, International Congress and Symposium Series No. 146, pp. 51–54.

    Google Scholar 

  • Dahan A, Yassen A, Bijl H, Romberg R, Sarton E, Teppema L, Olofsen E, Danhof M (2005): Comparison of the respiratory effects of intravenous buprenorphine and fentanyl in humans and rats. Br J Anaesth 94: 825–834.

    Article  PubMed  CAS  Google Scholar 

  • Drover DR, Angst MS, Valle M, Ramaswamy B, Naidu S, Stanski DR, Verotta D (2002): Input characteristics and bioavailability after administration of immediate and a new extended-release formulation of hydromorphone in healthy volunteers. Anesthesiology 97: 827–836.

    Article  PubMed  CAS  Google Scholar 

  • Frampton JE (2010): Tapentadol immediate release: a review of its use in the treatment of moderate to severe acute pain. Drugs 70: 1719–1743.

    Article  PubMed  CAS  Google Scholar 

  • Fürlan AD, Sandoval JA, Mailis-Gagnon A, Tunks E (2006): Opioids for chronic noncancer pain: a meta-analysis of effectiveness and side effects. CMAJ 174: 1589–1594.

    Article  PubMed  Google Scholar 

  • Hanks GW, De Conno F, Cherny N et al (Expert Working Group of the Research Network of the European Association for Palliative Care) (2001): Morphine and alternative opioids in cancer pain: the EAPC recommendations. Br J Cancer 84: 587–593.

    Article  PubMed  CAS  Google Scholar 

  • Jacox A, Carr DB, Payne R et al (Agency for Health Care Policy and Research (AHCPR) Pharmacological Management) (1994): Recommendations. In: Management of cancer pain. Clinical Practice Guideline No 9. U.S. Department of Health and Human Services, Public Health Service, AHCPR Publication No 94–0592, March, Rockville.

    Google Scholar 

  • Meissner W, Leyendecker P, Mueller-Lissner S, Nadstawek J, Hopp M, Ruckes C, Wirz S, Fleischer W, Reimer K (2009a): A randomised controlled trial with prolongedrelease oral oxycodone and naloxone to prevent and reverse opioid-induced constipation. Eur J Pain 13: 56–64.

    Article  CAS  Google Scholar 

  • Meissner W, Mueller-Lissner S, Nadstawek J, Hopp M, Ruckes C, Wirz S, Fleischer W, Reimer K, Leyendecker P (2009b): Dr. Meissner and colleagues reply to the Letter to the Editor from Andrew Wilcock entitled ‘Prolonged-release naloxone can cause systemic opioid withdrawal’. Eur J Pain 13: 1002–1003.

    Article  CAS  Google Scholar 

  • Radbruch L, Elsner F (2005): Palliative Schmerztherapie, Cannabinoide. Internist 46: 1105–1114.

    Article  PubMed  CAS  Google Scholar 

  • Ripamonti C, Fagnoni E, Campa T, Brunelli C, De Conno F (2006): Is the use of transdermal fentanyl inappropriate according to the WHO guidelines and the EAPC recommendations? A study of cancer patients in Italy. Support Care Cancer 14: 400–407.

    Article  PubMed  Google Scholar 

  • Quigley C (2002): Hydromorphone for acute and chronic pain. Cochrane Database Syst Rev. 2002 (1): CD003447.

    PubMed  Google Scholar 

  • Szelenyi I, Nickel B, Borbe HO, Brune K (1989): Mode of antinociceptive action of flupirtine in the rat. Br J Pharmacol 97: 835–842.

    PubMed  CAS  Google Scholar 

  • The Pain Society (2004): Recommendations for the appropriate use of opioids for persistent non-cancer pain. A consensus statement prepared on behalf of the Pain Society, the Royal College of Anaesthetists, the Royal College of General Practitioners and the Royal College of Psychiatrists. March 2004. Internet: www.britishpainsociety.org/pdf/opioids_doc_2004.pdf.

  • Wilcock A (2009): Prolonged-release naloxone can cause systemic opioid withdrawal. Eur J Pain 13: 1001 (2009).

    Article  PubMed  CAS  Google Scholar 

  • World Health Organization (WHO) (1986): Cancer Pain Relief. World Health Organization Publications, Geneva, Switzerland.

    Google Scholar 

  • World Health Organization (WHO) (1996): Cancer pain relief, 2nd edn. World Health Organization Publications, Geneva, Switzerland.

    Google Scholar 

  • Zhang WY, Po AL (1996): Analgesic efficacy of paracetamol and its combination with codeine and caffeine in surgical pain – a metaanalysis. J Clin Pharm Ther 21: 261–282.

    Article  PubMed  CAS  Google Scholar 

  • Zhang WY, Po AL (1997): Do codeine and caffeine enhance the analgesic effect of aspirin? A systematic overview. J Clin Pharm Ther 22: 79–97.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2011 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Böger, R.H., Schmidt, G. (2011). Analgetika. In: Schwabe, U., Paffrath, D. (eds) Arzneiverordnungs-Report 2011. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-21992-4_6

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-21992-4_6

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-21991-7

  • Online ISBN: 978-3-642-21992-4

  • eBook Packages: Medicine (German Language)

Publish with us

Policies and ethics