Ocular Lens Microcirculation Model, A Web-Based Bioengineering Educational Tool

Abstract

Currently a comprehensive computational model of the human body is being developed at the Auckland Bioengineering Institute. As a part of this project, the development of a global model of the human eye - the virtual eye- is also in progress. This multi-scale virtual eye model is being developed to enable a powerful educational tool for students and researchers as well as a novel form of integrative diagnosis or treatment for individuals, based on the clinical data gathered. One of the most important aspects of the ocular tissue is its fluid dynamics which is known to affect the physiological and optical properties of the eye.

During this project, a 3D finite element model of the fluid dynamics of the ocular lens was designed and executed on our high performance computer. This sophisticated computer model was then linked to a website, in order to elevate it from a local computer model to a global research and educational tool. The presentation of the 3D fluid microcirculation model of the ocular lens over the internet, combined with its user-friendly graphical user interface, has enabled it as a computer model to be used by students and researchers worldwide. Such exposure to the international lens community makes this model a unique debate point in order to obtain a better understanding of the ocular lens homeostasis and its role in the functionality.

Using the 3D microcirculation model to predict the effects of various perturbation conditions on the physiological and optical properties of the lens, could lead to better understanding of lens abnormalities such as cataracts and their causes. This model is particularly seen as a capability platform for the other ocular tissues’ fluid dynamic models to be linked into a single virtual eye platform, which is going to be accessible via the internet.