Abstract
Recent studies showed that gum-chewing induced significant increases in cerebral blood flow and blood-oxygenation level in the widespread brain regions. However, little is known about the underlying mechanism of chewing-induced regional interconnection and interaction within the brain. In this study, we investigated the human brain functional network during chewing of gum by using functional magnetic resonance imaging and complex network theory. Adjacency matrix of the network was constructed by the active voxels of chewing-related. The global statistical properties of the network revealed the brain functional network for chewing of gum had small-world effect and scale-free property. Computing the degree and betweenness which belong to the centrality indices, we found that the neocortical hubs of the network were distributed in the sense and motor cortex, and the nodes in the thalamus and lentiform nucleus held the largest betweenness. The sense and motor cortices as well as thalamus and lentiform nucleus have the important roles in dispatch and transfer information of network.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
References
Momose, I., Nishikawa, J., Watanabe, T., Sasaki, Y., Senda, M., Kubota, K., Sato, Y., Funakoshi, M., Minakuchi, S.: Effector of mastication on regional cerebral blood flow in humans examined by positron-emission tomography with 15O-labelled water and magnetic resonance imaging. Arch. Oral. Biol. 42(1), 57–61 (1997)
Kubota, K., Momose, T., Abe, A., Narita, N., Ohtomo, K., Minaguchi, S., Funakoshi, M., Sasaki, Y., Kojima, Y.: Nuclear medical PET-study in the causal relationship between mastication and brain function in human evolutionary and developmental processes. Ann. Anat. 185, 565–569 (2003)
Onozuka, M., Fujita, M., Watanabe, K., Hirano, Y., Niwa, M., Nishiyama, K., Saito, S.: Mapping Brain Region Activity during Chewing: A Functional Magnetic Resonance Imaging Study. J. Dent. Res. 81(11), 743–746 (2002)
Takada, T., Miyamoto, T.: A fronto-parietal network for chewing of gum: a study on human participants with functional magnetic resonance imaging. Neurosciece 360, 137–140 (2004)
Hirano, Y., Obata, T., Kashikura, K., Nonaka, H., Tachibana, A., Ikehira, H., Onozuka, M.: Effects of chewing in working memory processing. Neurosci. Lett. 436(2), 189–192 (2008)
Sporns, O., Chialvo, D.R., Kaiser, M., Hilgetag, C.C.: Organization, development and function of complex brain networks. Trends Cogn. Sci. 8, 418–425 (2004)
Salvador, R., Suckling, J., Schwarzbauer, C., Bullmore, E.: Undirected graphs of frequency-dependent functional connectivity in whole brain networks. Phil. Trans. R. Soc. B 360, 937–946 (2005)
Watts, D.J., Strogatz, S.H.: Collective dynamics of ”small-world” network”. Nature 393, 440–442 (1998)
Achard, S., Salvador, R., Whitcher, B., Suckling, J., Bullmore, E.D.: A Resilient, Low-Frequency,Small-World Human Brain Functional Network with Highly Connected Assocaition Cortical Hubs. The Journal of Neursoscience 26, 63–72 (2006)
Tzourio-Mazoyer, N., Landeau, B., Papathanassiou, D., Crivello, F., Etard, O., Delcroix, N., Mazoyer, B., Joliot, M.: Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain. NeuroImage 15, 273–289 (2002)
Eguíluz, V.M., Chialvo, D.R., Cecchi, G.A., Baliki, M., Apkarian, A.V.: Scale-free brain functional networks. Physical Review Letters 94, 018102 (2005)
Newman, M.E.J.: A measure of betweenness centrality based on random walks. Social Networks 27, 39–54 (2005)
Onozuka, M., Fujita, M., Watanabe, K., Hirano, Y., Niwa, M., Nishiyama, K., Saito, S.: Ages-related changes in brain regional activity during Chewing: A Functional Magnetic Resonance Imaging Study. J. Dent. Res. 82, 657–660 (2003)
Fallon, J.H., Opole, I.O., Potkin, S.G.: The neuroanatomy of schizophrenia: circuitry and neurotransmitter systems. J. Clinical Neuroscience Research 3, 77–107 (2003)
Kandel, E.R., Schwartz, J.H., Jessell, T.M.: Principles of neural science, 4th edn., New York, vol. 3, pp. 77–107 (2003)
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2011 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Ke, M., Shen, H., Zhou, Z., Zhou, X., Hu, D., Chen, X. (2011). Brain Functional Network for Chewing of Gum. In: Lee, R. (eds) Computer and Information Science 2011. Studies in Computational Intelligence, vol 364. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-21378-6_13
Download citation
DOI: https://doi.org/10.1007/978-3-642-21378-6_13
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-21377-9
Online ISBN: 978-3-642-21378-6
eBook Packages: EngineeringEngineering (R0)