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Atypical Cribriform Lesions of the Prostate Gland: Emerging Concepts of Intraductal Carcinoma of the Prostate (IDC-P)

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Abstract

Atypical cribriform lesions of the prostate gland consist of proliferation of cribriform glands lined by cytologically malignant cells with partial or complete basal cell lining. It may represent cribriform “high-grade prostatic intraepithelial neoplasia” (HGPIN) or “intraductal carcinoma of the prostate” (IDC-P), and are distinguished from cribriform prostate cancer by lack of confluent and/or infiltrative architecture and presence of basal cells [1]. In 1996, IDC-P was first proposed by McNeal and Yemoto [2], and several studies have attempted to further refine histologic definition of IDC-P in the past decade [1, 3–5]. IDC-P is almost always associated with clinically aggressive high-volume prostate carcinoma [1,6].

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References

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Correspondence to Rajal B. Shah M.D. .

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Shah, R.B., Zhou, M. (2012). Atypical Cribriform Lesions of the Prostate Gland: Emerging Concepts of Intraductal Carcinoma of the Prostate (IDC-P). In: Prostate Biopsy Interpretation: An Illustrated Guide. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-21369-4_8

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  • DOI: https://doi.org/10.1007/978-3-642-21369-4_8

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-21368-7

  • Online ISBN: 978-3-642-21369-4

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