Whole-Body Applications of DWI

  • Joan C. VilanovaEmail author
  • Sandra Baleato
  • Joaquim Barceló
  • Antonio Luna


DWI has revealed great potential in cancer and bone marrow imaging of the body. Whole-body DWI is a recent application, performing multiple stations and a composite image of the entire body. The true utility of WB-DWI has shown the potential and clinical values of this emerging technique for oncologic as well as for nononcologic applications. A complete WB-MRI protocol with standard sequences, DWI, and dynamic 3D contrast-enhanced acquisitions can be performed in less than 40 min of examination. WB-DWI has focused on the detection of osseous metastases in patients with primary malignancies that had the potential to metastasize to the skeletal system and multiple myeloma, and also in the evaluation of the therapeutic response in human bone marrow. WB-DWI is superior to bone scan and PET in the evaluation of bone marrow tumoral involvement. WB-DWI provides also additional information of the extraskeletal areas. DWI is useful to quantify the results with the ADC values, with several clinical applications such as the differentiation between acute benign fractures from malignant and infectious lesions. Further research, comparing and evaluating complementary roles of PET and WB-DWI, is still needed


Multiple Myeloma Bone Metastasis Restricted Diffusion Plexiform Neurofibroma Stir Sequence 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Further Reading

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Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • Joan C. Vilanova
    • 1
    Email author
  • Sandra Baleato
    • 2
  • Joaquim Barceló
    • 3
  • Antonio Luna
    • 4
  1. 1.Department of Radiology, Clínica Girona-Hospital Sta. CaterinaUniversity of GironaGironaSpain
  2. 2.Department of RadiologyComplexo Hospitalario Universitario de SantiagoSantiago de CompostelaSpain
  3. 3.Department of RadiologyClínica Girona-Hospital Sta. CaterinaGironaSpain
  4. 4.MRI sectionClínica Las Nieves, SERCOSAJaénSpain

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