Automatic Segmentation of Cardiac CTs - Personalized Atrial Models Augmented with Electrophysiological Structures
Electrophysiological simulations of the atria could improve diagnosis and treatment of cardiac arrhythmia, like atrial fibrillation or flutter. For this purpose, a precise segmentation of both atria is needed. However, the atrial epicardium and the electrophysiological structures needed for electrophysiological simulations are barely or not at all detectable in CT-images. Therefore, a model based segmentation of only the atrial endocardium was developed as a landmark generator to facilitate the registration of a finite wall thickness model of the right and left atrial myocardium. It further incorporates atlas information about tissue structures relevant for simulation purposes like Bachmann’s bundle, terminal crest, sinus node and the pectinate muscles. The correct model based segmentation of the atrial endocardium was achieved with a mean vertex to surface error of 0.53 mm for the left and 0.18 mm for the right atrium respectively. The atlas based myocardium segmentation yields physiologically correct results well suited for electrophysiological simulations.
Keywordsautomatic segmentation computed tomography cardiac atrium atrial fibrillation electrophysiological structures
Unable to display preview. Download preview PDF.
- 1.Jørgensen, H.S., et al.: The copenhagen stroke study (1996), http://stroke.ahajournals.org/ (accessed May 14, 2010)
- 2.Weber, F.M., Schilling, C., Straub, D., Gurm, S., Seemann, G., Lorenz, C., Dössel, O.: Extracting Clinically Relevant Circular Mapping and Coronary Sinus Catheter Potentials from Atrial Simulations. In: Ayache, N., Delingette, H., Sermesant, M. (eds.) FIMH 2009. LNCS, vol. 5528, pp. 30–38. Springer, Heidelberg (2009)CrossRefGoogle Scholar
- 3.Jacquemet, V., et al.: Modeling atrial arrhythmias: Impact on clinical diagnosis and therapies. IEEE Reviews in Biomedical Engineering 1 (2008)Google Scholar
- 8.Stehning, C., et al.: Black-blood restricted field of view sequence for pre-ablation imaging of the atria. Proc. Intl. Soc. Mag. Reson. Med. 18, 1409 (2010)Google Scholar
- 11.Si, H.: TetGen A Quality Tetrahedral Mesh Generator and Three-Dimensional Delaunay Triangulator. Weierstrass Institute for Applied Analysis and Stochastics. Version 1.4 edn. (2006)Google Scholar
- 15.Coffey, J., et al.: Specific absorbed fractions for photon sources uniformly distributed in the heart chambers and heart wall of a heterogeneous phantom. Journal of Nuclear Medicine 22, 65–71 (1981)Google Scholar