Integrated Molecular Circuits for Stem Cell Activity in Arabidopsis Roots

  • B. Scheres
Conference paper
Part of the Springer Proceedings in Mathematics book series (PROM, volume 15)


Pattern formation in biological systems has long been thought to emanate from hierarchical control systems. More recently, another view on the development of patterns has gained ground, where multilevel interactions (spanning molecular, cellular and organismal processes and allowing feedback between all levels) create different attractor states for the biological system. In moving towards attractor states, complicated patterns may ensue as an emergent property from simple interactions. We study these processes in plant development, because plant cells do not move relative to one another which facilitates analysis.


  1. 1.
    Aida M, Beis D, Heidstra R, Willemsen V, Blilou I, Galinha C, Nussaume L, Noh Y-S, Amasino R, Scheres B (2004) The PLETHORA genes mediate patterning of the Arabidopsis root stem cell niche. Cell 119:109–120CrossRefGoogle Scholar
  2. 2.
    Galinha C, Hofhuis H, Luijten M, Willemsen V, Blilou I, Heidstra R, Scheres B (2007) PLETHORA proteins as dose-dependent master regulators of Arabidopsis root development. Nature 449:1053–1057CrossRefGoogle Scholar
  3. 3.
    Grieneisen V, Xu J, Maré AFM, Hogeweg P, Scheres B (2007) Auxin transport is sufficient to generate maximum and gradient guiding root growth. Nature 449:1008–1013CrossRefGoogle Scholar
  4. 4.
    Wildwater M, Campilho A, Perez-Perez JM, Heidstra R, Blilou I, Korthout H, Chatterjee J, Mariconti L, Gruissem W, Scheres B (2005) The RETINOBLASTOMA-RELATED gene regulates stem cell maintenance in Arabidopsis roots. Cell 123:1337–1349CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  1. 1.Utrecht UniversityUtrechtThe Netherlands

Personalised recommendations