Adipose Stem Cell Engineering: Characterization and Current Application in Otolaryngology

Chapter

Abstract

The clinical potential for adipose-derived stem cell (ASC) is abundant and their capacity to differentiate into multiple lineages demonstrates the impact they can provide to regenerative therapies in otolaryngology – head and neck surgery. Adipose tissues have sufficient amounts of ASCs that can be derived from a single sample and harvested with minimally invasive procedures. Furthermore, ASCs can prevent the incidence of graft versus host disease by suppressing the immune response. Tissue engineering strategies can combine cell delivery with appropriate scaffold biomaterials that can mimic the unique physiological and biomechanical properties of ear, nose and throat. This chapter presents a review of the literature regarding the use of ASCs in otolaryngology head and neck surgery related research, illustrating their current and potential use in the field.

Keywords

Hyaluronic Acid Hepatocyte Growth Factor Vocal Fold Stromal Vascular Fraction Multilineage Differentiation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2011

Authors and Affiliations

  1. 1.Division of Otolaryngology Head and Neck Surgery, Department of SurgeryUniversity of Wisconsin - MadisonMadisonUSA

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