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Experiments on Computer Assisted Optimization of the EscherichiaColi Fermentation Process Using Optferm

  • Tânia Teixeira
  • Sérgio Deusdado
Part of the Advances in Intelligent and Soft Computing book series (AINSC, volume 93)

Abstract

We used the software Optferm to model and optimize the bioprocess of escherichia coli fermentation, simulating the conditions of a fed-batch bioreactor. The results, obtained by employing different AI approaches, provided useful orientation for nutrient feed strategies for increased productivity. In conclusion, we believe in silico tools can perform a rapid and valid optimization of bioprocesses avoiding expensive experiments.

Keywords

Simulated Annealing Differential Evolution Fermentation Process Butanol Production Interpolation Factor 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2011

Authors and Affiliations

  • Tânia Teixeira
    • 1
  • Sérgio Deusdado
    • 2
  1. 1.Superior Agrarian SchoolPolytechnic Institute of BragançaBragançaPortugal
  2. 2.CIMO – Mountain Research CenterPolytechnic Institute of BragançaBragançaPortugal

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