Measuring Bioactivity: KI, IC50 and EC50

  • Eric MarÉchalEmail author


Which quantity permits a characterisation of the performance of a bioactive molecule? How can a test be created so as to detect the effect of a molecule on a given target? Are there any general rules to respect? The design of a test is a complex problem dealt with in chapter 3; here we emphasise that, above all, the target must be a limiting factor in the reaction system.


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© Springer-Verlag Berlin Heidelberg 2011

Authors and Affiliations

  1. 1.Laboratory of Plant Cell Physiology, Institute of Life Sciences Research and Technologies CEACNRS - CEA - INRA - Joseph Fourier UniversityGrenobleFrance

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