Molecular Lipophilicity: A Predominant Descriptor for QSAR

  • Gérard Grassy
  • Alain Chavanieu


The discovery of a new medicine is a complex and costly process, in which the role of chance and fortuitous observation is often predominant. Substantial effort has been afforded to rationalise the discovery process as much as possible. The methodologies relevant to rational drug design (according to international terminology) are today omnipresent as much in academic research centres as in industry.


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© Springer-Verlag Berlin Heidelberg 2011

Authors and Affiliations

  • Gérard Grassy
    • 1
  • Alain Chavanieu
    • 1
  1. 1.Centre for Structural Biochemistry, Faculty of PharmacyCNRS - Servier - University of Montpellier - INSERMMontpellierFrance

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