Abstract
Cerebral blood flow and metabolism are generally interconnected. Alterations in brain function are associated with corresponding changes in perfusion. Radionuclide brain perfusion studies using lipophilic tracers are useful in the study of abnormalities of regional perfusion such as stroke and in the evaluation of changes related to neuronal activity like epilepsy and trauma. Their use in psychiatric conditions is promising. Several radiopharmaceuticals are used for imaging central nervous system. These include 99mTc HMPAO (Fig. 9.1), F-18 FDG (Fig. 9.2), and less commonly In111 DTPA.
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Further Reading
Gary R, Sinha P (2003) Scintigraphy as a confirmatory test of brain death. Semin Nucl Med 33:312
Ishibashi K, Saito Y, Murayama S, Kanemaru K, Oda K, Ishiwata K, Mizusawa H, Ishii K (2010) Validation of cardiac I-123 MIBG scintigraphy in patients with Parkinson disease who were diagnosed with dopa-mine PET. Eur J Nucl Med Mol Imaging 37:3–11
Mountz JM, San Pedro EC (2006) Basis and clinical application of functional brain imaging. In: Elgazzar AH (ed) Pathophysiologic basis of nuclear medicine, 2nd edn. Springer, Berlin
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Elgazzar, A.H. (2011). Central Nervous System. In: A Concise Guide to Nuclear Medicine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-19426-9_9
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DOI: https://doi.org/10.1007/978-3-642-19426-9_9
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