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Vergleich der lokalen Effektivität und des Metastasierungsverhaltens nach Resektion, Kryotherapie und Lasertherapie an einem colorectalen Tumormodell in der Leber der Ratte

Comparison of the local efficacy and pattern of metastases following resection, cryotherapy and laser therapy in a rat liver tumour model of colorectal cancer

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Chirurgisches Forum 2003 für experimentelle und klinische Forschung

Part of the book series: Deutsche Gesellschaft für Chirurgie ((FORUMBAND,volume 32))

Abstract

A rat colon cancer cell line (CC531) was implanted into the livers of 85 WAG rats and in animals surviving the implantation the liver tumour was subsequently treated with sham laparotomy (n = 15), resection (n = 20), cryotherapy (n = 19) or laser therapy (n = 20). Local recurrence or persistence of the tumour in animals surviving the procedure was observed in 15 of 15 following sham laparotomy, in 0 of 15 following resection, in 3 of 17 following cryotherapy and in 10 of 14 following laser therapy. However, peritoneal disease and lung metastases were more frequent and extensive following resection as compared to cryotherapy or laser therapy.

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Correspondence to J. K. Seifert .

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© 2003 Springer-Verlag Berlin Heidelberg

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Seifert, J.K., Becker, J., Burg, J., Dutkowski, P., Junginger, T. (2003). Vergleich der lokalen Effektivität und des Metastasierungsverhaltens nach Resektion, Kryotherapie und Lasertherapie an einem colorectalen Tumormodell in der Leber der Ratte. In: Menger, M.D., Haas, N.P., Neugebauer, E., Bauer, H. (eds) Chirurgisches Forum 2003 für experimentelle und klinische Forschung. Deutsche Gesellschaft für Chirurgie, vol 32. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-19024-7_50

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  • DOI: https://doi.org/10.1007/978-3-642-19024-7_50

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-00659-6

  • Online ISBN: 978-3-642-19024-7

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