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Neurogenesis in adult brain: understanding its mechanism and regulation

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Stem Cells in the Nervous System: Functional and Clinical Implications

Part of the book series: Research and Perspectives in Neurosciences ((NEUROSCIENCE))

Abstract

Adult neurogenesis is an intriguing phenomenon because of the promise it holds for leading to a new understanding of brain functions and in providing new therapeutic tools for regeneration and repair of diseased and injured adult CNS. We need to truly understand adult neurogenesis - what triggers it, what inhibits it and how it is regulated - before we can use this phenomenon appropriately.

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Authors and Affiliations

  1. Department of Neuroscience, School of Medicine, University of New Mexico, Albuquerque, NM, 87131, USA

    Xinyu Zhao

  2. Department of Chemical Engineering, University of California, Berkeley, CA, 94720, USA

    David Schaffer

  3. The Salk Institute for Biological Studies, 10010 N Torrey Pines Rd, La Jolla, CA, 92037, USA

    F. H. Gage

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  1. Xinyu Zhao
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  2. David Schaffer
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  3. F. H. Gage
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Editors and Affiliations

  1. The Salk Institute for Biological Studies, 10010 N. Torrey Pines Road, La Jolla, CA, 92037, USA

    Fred H. Gage Ph.D.

  2. Wallenberg Neurosciences Center Department of Physiological Sciences, Lund University, BMC A11, 22184, Lund, Sweden

    Anders Björklund M.D.

  3. Ecole Normale Supérieure and CNRS UMP8542, 46 rue d’Ulm, 75005, Paris, France

    Alain Prochiantz Ph.D.

  4. Fondation IPSEn Pour la Recherche Thérapeutique, 24, rue Erlanger, 75781, Paris Cedex 16, France

    Yves Christen Ph.D.

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Zhao, X., Schaffer, D., Gage, F.H. (2004). Neurogenesis in adult brain: understanding its mechanism and regulation. In: Gage, F.H., Björklund, A., Prochiantz, A., Christen, Y. (eds) Stem Cells in the Nervous System: Functional and Clinical Implications. Research and Perspectives in Neurosciences. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-18883-1_1

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