Abstract
Open surgical biopsy has long been considered the conventional gold standard for obtaining thoracic and abdominal lymph node samples in patients with lymphoma, especially for the original diagnosis. However, this procedure can have significant complications. With advances in cytopathologic diagnostic techniques, percutaneous image-guided needle biopsy with its high overall accuracy has become the procedure of choice, and is taking a prominent place in the management of lymphoma in both adults and children. It is now considered a relatively painless, quick, safe, low cost, and valuable tool for patients with suspected or recurrent lymphomas. A well-planned and executed biopsy provides an accurate diagnosis and facilitates treatment. CT is a widely available imaging modality and allows image-guided needle biopsy in a large majority of patients. US-guided biopsy is an alternative method of guidance and at some institutions is the guidance technique of choice. In this chapter, we will describe the technique and give some alternatives for when the procedure tends to be difficult, especially in posterior and/or deep-seated lymph nodes.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
References
Agid R, Sklair-Levy M, Bloom AI, Lieberman S, Polliack A, Ben-Yehuda D, Sherman Y, Libson E (2003) CT-guided biopsy with cutting-edge needle for the diagnosis of malignant lymphoma: experience of 267 biopsies. Clin Radiol 58: 143–147
Ben-Yehuda D, Polliack A, Okon E, Sherman Y, Fields S, Lebenshart P, Lotan H, Libson E (1996) Image-guided core-needle biopsy in malignant lymphoma: experience with 100 patients that suggests the technique is reliable. J Clin Oncol 14:2431–2434
Bressler EL, Kirkham JA (1994) Mediastinal masses: alternative approaches to CT-guided needle biopsy. Radiology 191:391–396
Carrasco CH, Richli WR, Lawrence D, Katz RL, Wallace S (1990) Fine needle aspiration biopsy in lymphoma. Radiol Clin North Am 28:879–883
Dachman AH (1998) A biopsy compression device for use in cross-sectional or fluoroscopic imaging. AJR Am J Roentgenol 171:703–705
de Kerviler E, Guermazi A, Cazals-Hatem D, Frija J (1996) Use of abdominal compression as an aid to CT-guided retroperitoneal biopsies. AJR Am J Roentgenol 167:1346–1347
de Kerviler E, Guermazi A, Gossot D, Cazals-Hatem D, Zagdanski AM, Mariette X, Brice P, Frija J (1998) Use of an abdominal compression device for CT-guided biopsy of enlarged abdominal or pelvic lymph nodes. J Vasc Interv Radiol 9:353–357
de Kerviler E, Guermazi A, Zagdanski AM, Meignin V, Gossot D, Oksenhendler E, Mariette X, Brice P, Frija J (2000) Image-guided core-needle biopsy in patients with suspected or recurrent lymphomas. Cancer 89:647–652
Demharter J, Muller P, Wagner T, Schlimok G, Haude K, Bohndorf K (2001) Percutaneous core-needle biopsy of enlarged lymph nodes in the diagnosis and subclassification of malignant lymphomas. Eur Radiol 11:276–283
Dodd GD 3rd, Esola CC, Memel DS, Ghiatas AA, Chintapalli KN, Paulson EK, Nelson RC, Ferris JV, Baron RL (1996) Sonography: the undiscovered jewel of interventional radiology. Radiographics 16:1271–1288
Esola CC, Chopra S, Dodd GD (1997) Sonographic guidance in biopsies and drainages: techniques and applications. Semin Intervent Rad 14:343–369
Fisher AJ, Paulson EK, Sheafor DH, Simmons CM, Nelson RC (1997) Small lymph nodes of the abdomen, pelvis, and retroperitoneum: usefulness of sonographically guided biopsy. Radiology 205:185–190
Garrett KM, Hoffer FA, Behm FG, Gow KW, Hudson MM, Sandlund JT (2002) Interventional radiology techniques for the diagnosis of lymphoma or leukemia. Pediatr Radiol 32:653–662
Haaga JR, Beale SM (1986) Use of CO2to move structures as an aid to percutaneous procedures. Radiology 161: 829–830
Hagberg H, Ahlstrom HK, Magnusson A, Sundstrom C, Astrom GK (2000) Value of transsternal core biopsy in patients with a newly diagnosed mediastinal mass. Acta Oncol 39:195–198
Hussain HK, Kingston JE, Domizio P, Norton AJ, Reznek RH (2001) Imaging-guided core biopsy for the diagnosis of malignant tumors in pediatric patients. AJR Am J Roentgenol 176:43–47
Hussain S (1996) Gantry angulation in CT-guided percutaneous adrenal biopsy. AJR Am J Roentgenol 166:537–539
Jeffrey RB, Jr. (1988) Coaxial technique for CT-guided biopsy of deep retroperitoneal lymph nodes. Gastrointest Radiol 13:271–272
Katada K, Kato R, Anno H, Ogura Y, Koga S, Ida Y, Sato M, Nonomura K (1996) Guidance with real-time CT fl uoroscopy: early clinical experience. Radiology 200:851–856
Kato R, Katada K, Anno H, Suzuki S, Ida Y, Koga S (1996) Radiation dosimetry at CT fluoroscopy: physician’s hand dose and development of needle holders. Radiology 201: 576–578
Langen HJ, Jochims M, Gunther RW (1995) Artifi cial displacement of kidneys, spleen, and colon by injection of physiologic saline and CO2as an aid to percutaneous procedures: experimental results. J Vasc Interv Radiol 6:411–416
Memel DS, Dodd GD, 3rd, Esola CC (1996) Effi cacy of sonography as a guidance technique for biopsy of abdominal, pelvic, and retroperitoneal lymph nodes. AJR Am J Roentgenol 167:957–962
Moulton JS (1993) Artifi cial extrapleural window for mediastinal biopsy. J Vasc Interv Radiol 4:825–829
Moulton JS, Moore PT (1993) Coaxial percutaneous biopsy technique with automated biopsy devices: value in improving accuracy and negative predictive value. Radiology 186: 515–522
Pappa VI, Hussain HK, Reznek RH, Whelan J, Norton AJ, Wilson AM, Love S, Lister TA, Rohatiner AZ (1996) Role of image-guided core-needle biopsy in the management of patients with lymphoma. J Clin Oncol 14:2427–2430
Protopapas Z, Westcott JL (1997) Transthoracic hilar and mediastinal biopsy. J Thorac Imaging 12:250–258
Protopapas Z, Westcott JL (2000) Transthoracic hilar and mediastinal biopsy. Radiol Clin North Am 38:281–291
Quinn SF, Sheley RC, Nelson HA, Demlow TA, Wienstein RE, Dunkley BL (1995) The role of percutaneous needle biopsies in the original diagnosis of lymphoma: a prospective evaluation. J Vasc Interv Radiol 6:947–952
Schweiger GD, Yip VY, Brown BP (2000) CT fl uoroscopic guidance for percutaneous needle placement into abdominopelvic lesions with difficult access routes. Abdom Imaging 25:633–637
Silverman SG, Lee BY, Mueller PR, Cibas ES, Seltzer SE (1994) Impact of positive fi ndings at image-guided biopsy of lymphoma on patient care: evaluation of clinical history, needle size, and pathologic findings on biopsy performance. Radiology 190:759–764
Sklair-Levy M, Polliack A, Shaham D, Applbaum YH, Gillis S, Ben-Yehuda D, Sherman Y, Libson E (2000) CT-guided core-needle biopsy in the diagnosis of mediastinal lymphoma. Eur Radiol 10:714–718
Sklair-Levy M, Lebensart PD, Applbaum YH, Ramu N, Freeman A, Gozal D, Gross E, Sherman Y, Bar-Ziv J, Libson E (2001) Percutaneous image-guided needle biopsy in children-summary of our experience with 57 children. Pediatr Radiol 31:732–736
Wittich GR, Nowels KW, Korn RL, Walter RM, Lucas DE, Dake MD, Jeffrey RB (1992) Coaxial transthoracic fi neneedle biopsy in patients with a history of malignant lymphoma. Radiology 183:175–178
Zinzani PL, Corneli G, Cancellieri A, Magagnoli M, Lacava N, Gherlinzoni F, Bendandi M, Albertini P, Baruzzi G, Tura S, Boaron M (1999) Core needle biopsy is effective in the initial diagnosis of mediastinal lymphoma. Haematologica 84:600–603
Zinzani PL, Colecchia A, Festi D, Magagnoli M, Larocca A, Ascani S, Bendandi M, Orcioni GF, Gherlinzoni F, Albertini P, Pileri SA, Roda E, Tura S (1998) Ultrasound-guided core-needle biopsy is effective in the initial diagnosis of lymphoma patients. Haematologica 83:989–992
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2004 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Guermazi, A., D. Dodd, G. (2004). Percutaneous Image-Guided Lymph Node Needle Biopsy. In: Guermazi, A. (eds) Radiological Imaging in Hematological Malignancies. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-18832-9_26
Download citation
DOI: https://doi.org/10.1007/978-3-642-18832-9_26
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-62313-4
Online ISBN: 978-3-642-18832-9
eBook Packages: Springer Book Archive