Skip to main content
SpringerLink
Log in
Book cover

Radiological Imaging in Hematological Malignancies pp 473–484Cite as

Abdominal Effects of Therapy in Patients Treated for Hematological Malignancies

  • Chapter

  • 177 Accesses

Part of the book series: Medical Radiology ((Med Radiol Diagn Imaging))

Abstract

With the advent of improved diagnostic modalities and aggressive therapy, various gastrointestinal complications of hematological malignancies are becoming more common. Abdominal complications of treated hematological malignancies are no longer a life-threatening event. Early diagnosis and treatment are crucial to improve morbidity of these conditions. However, clinical presentation and plain radiographic manifestations may be non-specific; barium studies may be hard to perform in these patients and carry a risk of bowel perforation. Abdominal US is first choice for patients with abdominal complaints. However, it is entirely operator dependent and significant artifacts caused by bowel gas may be a problem. MR imaging may take a long time and imaging findings of this modality are not yet well reported. CT provides the most comprehensive radiographic evaluation for the detection and characterization of abdominal conditions in such patients. This chapter reviews the important clinical aspects of abdominal complications of treated hematological malignancy and presents mainly CT images.

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Adams GW, Rauch RF, Kelvin FM, Silverman PM, Korobkin M (1985) CT detection of typhlitis. J Comput Assist Tomogr 9:363–365

    Article  PubMed  CAS  Google Scholar 

  • Alexander JE, Williamson SL, Seibert JJ, Golladay ES, Jimenez JF (1988) The ultrasonographic diagnosis of typhlitis (neutropenic colitis). Pediatr Radiol 18:200–204

    Article  PubMed  CAS  Google Scholar 

  • Barrett J (1991) Worldwide bone marrow transplantation in the last decade: new strategies in bone marrow transplantation. Wiely-Liss, New York, pp 1-6

    Google Scholar 

  • Benya EC, Sivit CJ, Quinones RR (1993) Abdominal complications after bone marrow transplantation in children: sonographic and CT findings. AJR Am J Roentgenol 161: 1023–1027

    PubMed  CAS  Google Scholar 

  • Brown BP, Abu-Yousef M, Farner R, LaBrecque D, Gingrich R (1990) Doppler sonography: a noninvasive method for evaluation of hepatic venocclusive disease. AJR Am J Roentgenol 154:721–724

    PubMed  CAS  Google Scholar 

  • Champlin RE, Gale RP (1984) The early complications of bone marrow transplantation. Semin Hematol 21:101–108

    PubMed  CAS  Google Scholar 

  • Cohen EP, Lawton CA, Moulder JE (1995) Bone marrow transplant nephropathy: radiation nephritis revisited. Nephron 70:217–222

    Article  PubMed  CAS  Google Scholar 

  • Cruz-Correa M, Poonawala A, Abraham SC, Wu TT, Zahurak M, Vogelsang G, Kalloo AN, Lee LA (2002) Endoscopic findings predict the histologic diagnosis in gastrointestinal graft-versus-host disease. Endoscopy 34:808–813

    Article  PubMed  CAS  Google Scholar 

  • Day DL, Carpenter BL (1993) Abdominal complications in pediatric bone marrow transplant recipients. Radiographics 13:1101–1112

    PubMed  CAS  Google Scholar 

  • Del Fava RL, Cronin TG Jr (1977) Typhlitis complicating leukemia in an adult: barium enema findings. AJR Am J Roentgenol 129:347–348

    PubMed  CAS  Google Scholar 

  • Dewar GJ, Lim CN, Michalyshyn B, Akabutu J (1981) Gastrointestinal complications in patients with acute and chronic leukemia. Can J Surg 24:67–71

    PubMed  CAS  Google Scholar 

  • Dieterich DT, Rahmin M (1991) Cytomegalovirus colitis in AIDS: presentation in 44 patients and a review of the literature. J Acquir Immune Defic Syndr 4 (Suppl 1):S29–35

    PubMed  Google Scholar 

  • Donnelly LF, Morris CL (1996) Acute graft-versus-host disease in children: abdominal CT findings. Radiology 199: 265–268

    PubMed  CAS  Google Scholar 

  • Ferrara JL, Deeg HJ (1991) Graft-versus-host disease. N Engl J Med 324:667–674

    Article  PubMed  CAS  Google Scholar 

  • Francis IR, Glazer GM (1982) Case report. Burkitt’s lymphoma of the pancreas presenting as acute pancreatitis. J Comput Assist Tomogr 6:395–397

    Article  PubMed  CAS  Google Scholar 

  • Frick MP, Maile CW, Crass JR, Goldberg ME, Delaney JP (1984) Computed tomography of neutropenic colitis. AJR Am J Roentgenol 143:763–765

    PubMed  CAS  Google Scholar 

  • Herbetko J, Grigg AP, Buckley AR, Phillips GL (1992) Venoocclusive liver disease after bone marrow transplantation: findings at duplex sonography. AJR Am J Roentgenol 158: 1001–1005

    PubMed  CAS  Google Scholar 

  • Hunter TB, Bjelland JC (1984) Gastrointestinal complications of leukemia and its treatment. AJR Am J Roentgenol 142 513–518

    PubMed  CAS  Google Scholar 

  • Jacoby WT, Cohan RH, Baker ME, Leder RA, Nadel SN, Dunnick NR (1990) Ovarian vein thrombosis in oncology patients: CT detection and clinical significance. AJR Am J Roentgenol 155:291–294

    PubMed  CAS  Google Scholar 

  • Jones B, Kramer SS, Saral R, Beschorner WE, Yolken RH, Townsend TR, Yeager AM, Lake A, Tutschka P, Santos GW (1988) Gastrointestinal infl ammation after bone marrow transplantation: graft-versus-host disease or opportunistic infection? AJR Am J Roentgenol 150:277–281

    PubMed  CAS  Google Scholar 

  • Kaste SC, Rodriguez-Galindo C, Furman WL (1999) Imaging pediatric oncologic emergencies of the abdomen. AJR Am J Roentgenol. 173:729–736

    PubMed  CAS  Google Scholar 

  • Kawamoto S, Horton KM, Fishman EK (1999) Pseudomembranous colitis: spectrum of imaging findings with clinical and pathologic correlation. Radiographics 19:887–897

    PubMed  CAS  Google Scholar 

  • Kelly CP, Pothoulakis C, LaMont JT (1994) Clostridium difficile colitis. N Engl J Med 330:257–262

    Article  PubMed  CAS  Google Scholar 

  • McDonald GB, Shulman HM, Sullivan KM, Spencer GD (1986) Intestinal and hepatic complications of human bone marrow transplantation. Part I. Gastroenterology 90:460–477

    CAS  Google Scholar 

  • Moir DH, Bale PM (1976) Necropsy findings in childhood leukaemia, emphasizing neutropenic enterocolitis and cerebral calcification. Pathology 8:247–258

    Article  PubMed  CAS  Google Scholar 

  • Murray JG, Evans SJ, Jeffrey PB, Halvorsen RA (1995) Cytomegalovirus colitis in AIDS: CT features. AJR Am J Roentgenol 165:67–71

    PubMed  CAS  Google Scholar 

  • Myerowitz RL, Pazin GJ, Allen CM (1977) Disseminated candidiasis. Changes in incidence, underlying diseases, and pathology. Am J Clin Pathol 68:29–38

    Google Scholar 

  • Niccolini DG, Graham JH, Banks PA (1976) Tumor-induced acute pancreatitis. Gastroenterology 71:142–145

    PubMed  CAS  Google Scholar 

  • Pastakia B, Shawker TH, Thaler M, O’Leary T, Pizzo PA (1988) Hepatosplenic candidiasis: wheels within wheels. Radiology 166:417–421

    PubMed  CAS  Google Scholar 

  • Patzik SB, Smith C, Kubicka RA, Kaizer H (1991) Bone marrow transplantation: clinical and radiologic aspects. Radiographics 11:601–610

    PubMed  CAS  Google Scholar 

  • Prolla JC, Kirsner JB (1964) The gastrointestinal lesions and complication of the leukemias. Ann Intern Med 61: 1084–1103

    PubMed  CAS  Google Scholar 

  • Rosenberg RF, Caridi JG (1983) Vincristine-induced megacolon. Gastrointest Radiol 8:71–73

    Article  PubMed  CAS  Google Scholar 

  • Shapiro RS, McClain K, Frizzera G, Gajl-Peczalska KJ, Kersey JH, Blazar BR, Arthur DC, Patton DF, Greenberg JS, Burke B (1988) Epstein-Barr virus associated B cell lymphoproliferative disorders following bone marrow transplantation. Blood 71:1234–1243

    PubMed  CAS  Google Scholar 

  • Shirkhoda A (1987) CT fi ndings in hepatosplenic and renal candidiasis. J Comput Assist Tomogr 11:795–798

    Article  PubMed  CAS  Google Scholar 

  • Spiegel RJ, Magrath IT (1979) Tumor lysis pancreatitis. Med Pediatr Oncol 7:169–172

    Article  PubMed  CAS  Google Scholar 

  • Sullivan KM, Deeg HJ, Sanders JE, Shulman HM, Witherspoon RP, Doney K, Appelbaum FR, Schubert MM, Stewart P, Springmeyer S (1984) Late complications after marrow transplantation. Semin Hematol 21:53–63

    PubMed  CAS  Google Scholar 

  • Underwood TW, Frye CB (1993) Drug-induced pancreatitis. Clin Pharm 12:440–448

    PubMed  CAS  Google Scholar 

  • Wagner ML, Rosenberg HS, Fernbach DJ, Singleton EB (1970) Typhlitis: a complication of leukemia in childhood. Am J Roentgenol Radium Ther Nucl Med 109:341–350

    PubMed  CAS  Google Scholar 

  • Wall SD, Jones B (1992) Gastrointestinal tract in the immunocompromised host: opportunistic infections and other complications. Radiology 185:327–335

    PubMed  CAS  Google Scholar 

  • Winton PR, Gwynn AM, Roberts JC, Thomas L (1975) Leukemia and the bowel. Med J Aust 131:723–724

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Radiology, St. Mary’s Hospital, 422 Tusbukuhonmachi, Kurume City, Fukuoka, 830-8543, Japan

    Nobufusa Furukawa

  2. Department of Radiology, University of California, San Francisco, 350 Parnassus Avenue, Suite 150, San Francisco, CA, 94117, USA

    Ali Guermazi

Authors
  1. Nobufusa Furukawa
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Ali Guermazi
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Radiographic Laboratory Osteporosis & Arthritis Research Group, University of California, San Francisco, 350 Pernassus Avenue, Suite 150, San Francisco, CA, 94117, USA

    Ali Guermazi MD (Visiting Associate Professor Department of Radiology, Director) (Visiting Associate Professor Department of Radiology, Director)

Rights and permissions

Reprints and permissions

Copyright information

© 2004 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Furukawa, N., Guermazi, A. (2004). Abdominal Effects of Therapy in Patients Treated for Hematological Malignancies. In: Guermazi, A. (eds) Radiological Imaging in Hematological Malignancies. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-18832-9_24

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-18832-9_24

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-62313-4

  • Online ISBN: 978-3-642-18832-9

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation