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Nuclear Medicine in Psychiatry pp 301–310Cite as

Schizophrenia and Psychotic Disorder

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Abstract

It is clear that SPET and PET scanning methods have been of key importance in furthering the understanding of the pathophysiology of schizophrenia. The unique ability to image receptor flux in living subjects is vital to understanding this condition, in which the locus of disease is likely to be at the molecular, or neurotransmitter level. Work so far has concentrated mainly on the involvement of dopamine in schizophrenia, but this is not likely to be the whole story. As new ligands are developed, further insights will be gained in the underlying pathology in schizophrenia. New techniques combining functional imaging with genetic studies are likely to be of increasing importance in the coming years, and interest in neural plasticity will mean that future work will not simply be static analysis of receptor populations but will concentrate more on long-term dynamic changes induced by the illness and its treatments.

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Authors and Affiliations

  1. Institute of Psychiatry, De Crespigny Park, Denmark Hill, London, SE5 8AF, UK

    James Stone & Lyn S. Pilowsky

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  1. James Stone
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  2. Lyn S. Pilowsky
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Editors and Affiliations

  1. Division of Nuclear Medicine, University Hospital Ghent, De Pintelaan 185, 9000, Gent, Belgium

    Andreas Otte  & Rudi A. Dierckx  & 

  2. University Department of Psychiatry, University Hospital Ghent, De Pintelaan 185, 9000, Gent, Belgium

    Kurt Audenaert  & Kees van Heeringen  & 

  3. Department of Medical Imaging Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820, Merelbeke, Belgium

    Kathelijne Peremans

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© 2004 Springer-Verlag Berlin Heidelberg

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Stone, J., Pilowsky, L.S. (2004). Schizophrenia and Psychotic Disorder. In: Otte, A., Audenaert, K., Peremans, K., van Heeringen, K., Dierckx, R.A. (eds) Nuclear Medicine in Psychiatry. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-18773-5_18

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  • DOI: https://doi.org/10.1007/978-3-642-18773-5_18

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-62287-8

  • Online ISBN: 978-3-642-18773-5

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