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Meshes: Benefits and Risks pp 161–169Cite as

Pathophysiology and Pathology of the Foreign-Body Reaction to Mesh Implants

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Abstract

Modern hernia surgery is no longer imaginable without the application of surgical meshes. Presently approximately 1 million meshes are implanted worldwide per year. The net-like alloplastic mesh is used to close the hernial gap and, with extended overlap, to reinforce the abdominal wall (Luijendijk et al. 2000). However, despite the increasing number of implantations, our knowledge about the tissue response to implanted meshes in humans and their long-term biocompatibility is still poor. Nearly all the data about the biological behaviour of these implants are obtained from animal experiments.

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Authors
  1. F. A. Offner
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Editors and Affiliations

  1. RWTH Aachen Klinikum, Chirurgische Universitätsklinik, Pauwelstraße 30, 52074, Aachen, Germany

    Volker Schumpelick

  2. Dept. Surgery (M/C 958), University of Illinois, South Wood Street 840, 60612-7322, Chicago, IL, USA

    Lloyd M. Nyhus

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© 2004 Springer-Verlag Berlin Heidelberg New York

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Offner, F.A. (2004). Pathophysiology and Pathology of the Foreign-Body Reaction to Mesh Implants. In: Schumpelick, V., Nyhus, L.M. (eds) Meshes: Benefits and Risks. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-18720-9_15

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  • DOI: https://doi.org/10.1007/978-3-642-18720-9_15

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-40757-7

  • Online ISBN: 978-3-642-18720-9

  • eBook Packages: Springer Book Archive

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