Skip to main content
SpringerLink
Log in

Risiko, Prävention und Vorsorgeuntersuchungen

  • Chapter
Management des Magen- und Ösophaguskarzinoms

Part of the book series: Onkologie aktuell ((ONKAKTUELL))

  • 55 Accesses

Zusammenfassung

➲ Aufgrund der Lokalisation eines Karzinoms in der Speiseröhre oder im Magen und der damit verbundenen relativ leichten Zugänglichkeit durch endoskopische Diagnostik kommt der Risikobeurteilung einer Karzinomentwicklung sowie den damit verbundenen Möglichkeiten an Vorsorgeuntersuchungen und Prävention eine besondere Bedeutung zu.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 59.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 79.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 99.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  • Altorki NK, Sunagawa M, Little AG, Skinner DB (1991 ) High-grade dysplasia in the columnar-lined esophagus. Am J Surg 161:97–99

    Article  PubMed  CAS  Google Scholar 

  • Appelqvist P, Salmo M (1980) Lye corrosion carcinoma of the esophagus. Cancer 45:2655

    Article  PubMed  CAS  Google Scholar 

  • Arnott SJ, Pearson JG, Finlayson ND, Shearman DJC (1971 ) The association of squamous esophageal cancer an thyroid disease. Br J Cancer 25:33

    Article  PubMed  CAS  Google Scholar 

  • Attwood SEA, Barlow AP, Norris TL, Watson A (1992) Barrett’s oesophagus:effects of antireflux surgery on symptom control and development of complications. Br J Surg 79:1050–1053

    Article  PubMed  CAS  Google Scholar 

  • Beresford SAA (1985) Is nitrate in the drinking water associated with the risk of cancer in the urban UK? Int J Epidemiol 14:57

    Article  PubMed  CAS  Google Scholar 

  • Bloss RS, Miller TA, Copeland EM (1980) Carcinoma of the stomach in the young adult. Surg Gynecol Obstet 150:883

    PubMed  CAS  Google Scholar 

  • Blot WJ, Devesa SS, Fraumeni Jr JR (1993) Continuing climb in rates of esophageal adenocarcinoma:an update. JAMA 270:1320

    Article  PubMed  CAS  Google Scholar 

  • Bonavina L, Ceriani C, Carazzone A, Segalin A, Ferrero S, Peracchia A (1999) Endoscopic laser ablation of nondysplastic Barrett’s epithelium: is it worthwhile? Gastrointest Surg 3:194–199

    Article  CAS  Google Scholar 

  • Bosseckert H, Rabbe G (1983) Multiple polyps in the stomach-how many polyps should be ectomized. Endoscopy 15:150

    Article  PubMed  Google Scholar 

  • Brand DL, Ylvisaker JT, Gelfand M, Pope CE (1980) Regression of columnar esophagus (Barrett’s) epithelium after antireflux surgery. N Engl J Med 102:844–888

    Article  Google Scholar 

  • Bremner CG, DeMeester TR (1998) Pathology and pathogenesis of Barrett’s esophagus. In: Proceedings from an international conference on ablation therapy for Barrett’s mucosa. Dis Esophagus 11:1–27

    CAS  Google Scholar 

  • Brown L, Swanson C, Gridley G et al. (1995) Adenocarcinoma of the esophagus. Role of obesity and diet. J Natl Cancer Inst 87:104–109

    Article  PubMed  CAS  Google Scholar 

  • Cameron AJ, Carpenter HA (1997) Barrett’s Barrett’s esophagus, high-grade dysplasia, and early adenocarcinoma: a pathological study. Am J Gastroenterol 92:586–591

    PubMed  CAS  Google Scholar 

  • Cameron AJ, Lomboy CT, Pera M, Carpenter HA (1995) Adenocarcinoma of the Esophagogastric Junction and Barrett’s Esophagus. Gastroenterology 109:1541–1546

    Article  PubMed  CAS  Google Scholar 

  • Cameron AJ, Ott BJ, Payne WS (1985) The incidence of adenocarcinoma in columnar-lined (Barrett’s) esophagus. N Engl J Med 313:857–859

    Article  PubMed  CAS  Google Scholar 

  • Chen VW, Abus-Elyazeed RR, Zavala DE et al. (1990) Riskfactors of gastric precancerous lesions in a high-risk Colombian population. Nitrate Nitrite Nutr Cancer 13:67

    CAS  Google Scholar 

  • Chen LQ, Hu CY, Ghadirian P, Duranceau A (1999) Early detection of esophageal squamous cell carinoma and ist effects on therapy:an overview. Dis Esophagus 12:161–167

    Article  PubMed  CAS  Google Scholar 

  • Chow W, Blot W, Baughan T et al. (1998) Body mass index and riskof adenocarcinoma of the esophagus and gastric cardia.J Natl Cancer Inst 90:150–155

    Article  PubMed  CAS  Google Scholar 

  • Chow W, Finkle W, McLaughlin J, Frankl H, Ziel H, Fraumeni J (1995) The relation of gastroesophageal reflux disease and its treatment to adenocarcinoma of the esophagus and gastric cardia. JAMA 274: 474–477

    Article  PubMed  CAS  Google Scholar 

  • Clark GWB, Smyrk TC, Burdiles P et al. (1994) Is Barrett’s metaplasia the source of adenocarcinomas of the cardia? Arch Surg 129:609–614

    Article  PubMed  CAS  Google Scholar 

  • Coordinating group for research in esophageal cancer-Linhsien County, Honan (1976) Early diagnosis and surgical treatment of esophageal cancer under rural conditions. Chin Med J 2:113

    Google Scholar 

  • Correa P, Fontham E, Pickle LW et al. (1985) Dietary determinants of gastric cancer in south Louisiana inhabitants. J Natl Cancer Inst 75:645

    PubMed  CAS  Google Scholar 

  • Cuello C, Correa P, Haenszel W et al. (1976) Gastric cancer in clomba:Cancer risk and suspect environmental agents. J Natl Cancer Inst 537: 1015

    Google Scholar 

  • DeMeester TR, Attwood SEA, Smyrk TC, Therkildsen DH, Hinder RA (1990) Surgical therapy in Barrett’s esophagus. Ann Surg 212: 528–540

    Article  PubMed  CAS  Google Scholar 

  • De Meester SR, De Meester TR (2000) Columnar mucosa and intestinal metaplasia of the esophagus. Fifty years of controversy. Ann Surg 231:303–321

    Article  Google Scholar 

  • Edwards MJ, Gable DR, Lentsch AB, Richardson DJ (1996) The Rationale for Esophagectomy as the optimal therapy for Barrett’s esophagus with high-grade dysplasia. Ann Surg 223:585–591

    Article  PubMed  CAS  Google Scholar 

  • Eng C, Spechler S, Ruben R, Li F (1993) Familial Barrett esophagus and adenocarcinoma of the gastroesophageal junction. Cancer Epidemiol Biomarkers Prev 2:397–399

    PubMed  CAS  Google Scholar 

  • Fahmy N, King J (1993) Barrett’s esophagus:an acquired condition with genetic predisposition. Am J Gastroenterol 88:1262–1265

    PubMed  CAS  Google Scholar 

  • Falk GW, Rice TW, Goldblum JR, Richter JE et al. (1999) Jumbo biopsy forceps protocol still misses unsuspected cancer in Barrett’s esophagus with high-grade dysplasia. Gastrointest Endosc 49:170–176

    Article  PubMed  CAS  Google Scholar 

  • Ferguson MK, Naunheim KS (1997) Resection for Barrett’s mucosa with high-grade dysplasia: implications for prophylactic photodynamic therapy. J Thorac Cardiovasc Surg 114:824–829

    Article  PubMed  CAS  Google Scholar 

  • Ferraris R, Bonelli L, Conio M, Fracchia M, Lapertosa G, Aste H (1997) Incidence of Barrett’s adenocarcinoma in an Italian population:an endoscopic surveillance programme. Gruppo Operativo per lo Studio delle Precancerosi Esofagee (GOSPE). Eur J Gastroenterol Hepatol 9 (9): 881–885

    Article  PubMed  CAS  Google Scholar 

  • Froelicher P, Miller G (1986) The European experience with esophageal cancer limited to the mucosa and submucosa. Gastrointest Endosc 32:88

    Article  PubMed  CAS  Google Scholar 

  • Gammon M, Schoenberg J, Ahsan H et al. (1997) Tobacco, alcohol, and socioeconomic status and adenocarcinomas of the esophagus and gastric cardia. J Natl Cancer Inst 89:1277–1284

    Article  PubMed  CAS  Google Scholar 

  • Graham S, Haughey B, Marshall J et al. (1990) Diet in the epidemiology of gastric cancer. Nutr Cancer 13:19

    Article  PubMed  CAS  Google Scholar 

  • Grunewald M, Vieth M, Kreibich H, Bethke B, Stolte M (1997) Untersuchungen zum Stand der Diagnostik des Barrett-Ösophagus. Dtsch Med Wochenschr 122:427–431

    Article  PubMed  CAS  Google Scholar 

  • Guojun H, Lingfang S, Dawei Z et al. (1981 ) Diagnosis and surgical treatment of early esophageal carcinoma. Chin Med J 94:229

    Google Scholar 

  • Haggit RC, Tryzelaar J, Ellis FH, Colcher H (1978) Adenocarcinoma complicating columnar-epithelium-lined (Barrett’s) esophagus. Am J Clin Pathol 70:1

    Google Scholar 

  • Hameeteman W, Tytgat GNJ, Houthoff HJ, Van Den Tweel JG (1989) Barrett’s esophagus: development of dysplasia and adenocarcinoma. Gastroenterology 96:1249–1256

    PubMed  CAS  Google Scholar 

  • Hamilton SR, Smith RR (1997) The relationship between columnar epithelial dysplasia and invasive adenocarcinoma arising in Barrett’s esophagus. Am J Clin Pathol 87:301–312

    Google Scholar 

  • Heitmiller RF, Redmond M, Hamilton SR (1996) Barrett’s esophagus with high-grade dysplasia. An indication for prophylactic esopahgectomy. Ann Surg 224:66–71

    Article  PubMed  CAS  Google Scholar 

  • Hirota W, Loughney T, Lazas D, Maydonovitch C, Rholl V, Wong R (1999) Specialized intestinal metaplasia, dysplasia, and cancer of the esophagus and esophagogastric junction: prevalence and clinical data. Gastroenterology 116:277–285

    Article  PubMed  CAS  Google Scholar 

  • Hölscher A, Gutschow KTE, Schneider P (1998) What is the evolution of Barrett’s mucosa after antireflux surgery? In: Guili R (ed) The esophagogastric junction. OESO, John Libbey Eurotext, Paris: pp 1047–1052

    Google Scholar 

  • Huang J, Subbaramiah S, Chen Y, Hunt R (1998) Meta-analysis of the relationship between Helicobacter pylori seropositivity and gastric cancer. Gastroenterology 114:1169–1179

    Article  PubMed  CAS  Google Scholar 

  • Iftikhar SY, James PD, Steele RJ, Hardcastle JD, Atkinson M (1993) Lenght of Barrett’s oesophagus:an important factor in the development of dysplasia and adenocarcinoma. Gut 33(9): 1155–1158

    Article  Google Scholar 

  • Jankowski JA, Wright NA, Meltzer SJ et al. (1999) Molecular Evolution of the metaplasia-Dysplasia-Adenocarinoma Sequence in the Esophagus. Am J Pathol 154:965–973

    Article  PubMed  CAS  Google Scholar 

  • Jedrychowski W, Wahrendorf J, Popiela T, Rachtan J (1986) A case-control study of dietary factors and stomach cancer risk in Poland. Int J Cancer 37:837

    Article  PubMed  CAS  Google Scholar 

  • Klinkenberg-Knol EC, Nelis F, Dent J et al. (2000) Long-term Omeprazole treatment in resistant gastroesophageal reflux disease: efficacy, safety, and influence on gastric mucosa. Gastroenterology 118: 661–669

    Article  PubMed  CAS  Google Scholar 

  • Knight TM, Forman D, Pirastu R et al. (1990) Nitrate and nitrite exposure in Italian populations with different gastric cancer rates. Int J Epidemiol 19:510

    Article  PubMed  CAS  Google Scholar 

  • Lagergren J, Bergström R, Lindgren A, Nyrén O (1999) Symptomatic gastroesophageal reflux as a risk factor for esophageal adenocarcinoma. NE 340:825–831

    Article  CAS  Google Scholar 

  • La Vecchia CL, Liati P, Decarli A et al. (1986) Tar yields of cigarettes and the risk of oesophageal cancer. Int J Cancer 38:381

    Article  PubMed  CAS  Google Scholar 

  • Levine DS, Haggitt RC, Blount PL, Rabinovitch PS, Rusch VW, Reid BR (1993) An endoscopic biopsy protocol can differentiate highgrade dysplasia from early adenocarcinoma in Barrett’s esophagus. Gastroenterology 105:40–50

    PubMed  CAS  Google Scholar 

  • Mecklin JP, Nording S, Sagrio I (1988) Carcinoma of the stomach and its heredity in young patients. Scand J Gastroenterol 23:307

    Article  PubMed  CAS  Google Scholar 

  • Ming S (1977) The classification and significance of gastric polyps. In: International Academy of Pathology Monograph-the gastrointestinal tract: 149

    Google Scholar 

  • Murson BC, Sobin LH, Grundmann E et al. (1980) Precancerous condition and epithelial dysplasia in the stomach. J Clin Pathol 33:19

    Article  Google Scholar 

  • Ortiz A, Martinez de Haro LF, Parilla P et al. (1996) Conservative treatment versus antireflux surgery in Barrett’s oesophagus:long-term results of a prospective study. Br J Surg 83:274–278

    Article  PubMed  CAS  Google Scholar 

  • Parsonnett J, Friedman G, Vandersteen DP et al. (1991 ) Helicobacter pylori infection and the risk of gastric carcinoma. N Engl J Med 325: 1127–1131

    Article  Google Scholar 

  • Pera M, Cameron AJ, Trastek VF, Carpenter HA, Zinsmeister AR (1993) Increasing incidence of adenocarcinoma of the esophagus and esophagogastric junction. Gastroenterology 104:510–513

    PubMed  CAS  Google Scholar 

  • Pera M, Fernandez PL, Pera M etal. (2001 ) Expression of cyclin D1 and p53 and ist correlation with proliferative activity in the spectrum of esophageal carcinomas induced after duodenal content reflux and 2, 6-dimethylnitrosomorpholine administration in rats. Carcinogenesis 22/2:271–277

    Article  Google Scholar 

  • Pera M, Trastek VF, Carpentier HA, Allen MS, Deschamps C, Pairolero PC (1992) Barrett’s esophagus with high-grade dysplasia: an indication for esophagectomy? Ann Thorac Surg 54:199–204

    Article  PubMed  CAS  Google Scholar 

  • Peters JH, Clark G, Ireland A et al. (1994) Ooutcome of adenocarcinoma arising in Barrett’s esophagus in endoscopically surveyed and non-surveyed patients. J Thorac Cardiovasc Surg 108:813–822

    PubMed  CAS  Google Scholar 

  • Rice TW, Falk GW, Achkar E, Petras RE (1993) Surgical management of high-grade dysplasia in Berrett’s esophagus. Am J Gastroenterol 88:1832–1836

    PubMed  CAS  Google Scholar 

  • Risch HA, Jain M, Choi NW et al. (1985) Dietary factors and the incidence of cancer of the stomach. Am J Epidemiol 122:947

    PubMed  CAS  Google Scholar 

  • Romero Y, Cameron A, Locke R et al. (1997) Familial aggregation of gastroesphageal reflux in patients with Barrett’s esophagus and esophageal adenocarinoma. Gastroenterlogy 113:1449–1456

    Article  CAS  Google Scholar 

  • Sagar PM, Ackroyd R, Hosie KB et al. (1995) Regression and progression of Barrett’s esophagus after antireflux surgery. Br J Surg 82:806–810

    Article  PubMed  CAS  Google Scholar 

  • Sampliner RE, Faigel D, Fennerty MB et al. (2001 ) Effective and safe endoscopic reversal of nondysplastic Barrett’s esophagus with high-dose acid inhibition: a multicenter study. Gastrointest Endoscopy 53:554–558

    Article  CAS  Google Scholar 

  • Sandler RS, Johnson MD, Holland KL (1984) Risk of stomach cancer after gastric surgery for benign conditions. A case-control study. Dig Dis Sci 29:703

    Article  PubMed  CAS  Google Scholar 

  • Schnell TG, Sonntag SJ, Chejfec A (1992) Adenocarcinomas arising in tongues or short segments of Barrett’s esophagaus. Dig Dis 37: 137–143

    Article  CAS  Google Scholar 

  • Schwindt WD, Berhardt LC, Johnson SA (1970) Tylosis and intrathoracic neoplasms. Chest 57:590

    Article  PubMed  CAS  Google Scholar 

  • Spechler SJ, Goyal RK (1986) Barrett’s esophagus. N Engl J Med 315: 362–371

    Article  PubMed  CAS  Google Scholar 

  • Spechler SJ, Zeroogian JM, Antonioli DA, Wang HH, Goyal RK (1994) Prevalence of metaplasia at the gastro-oesophageal junction. Lancet 344:1533–1536

    Article  PubMed  CAS  Google Scholar 

  • Stalnikowicz R, Benbassat J (1990) Risk of gastric cancer after gastric surgery for benign disorders. Arch Int Med 150:2022

    Article  CAS  Google Scholar 

  • Streitz JM, Andrews CW, Ellis FH (1993) Endoscopic surveillance of Barrett’s esophagus. Does it help? J Thorac Cardiovasc Surg 105: 383–387

    PubMed  Google Scholar 

  • The EUROGAST Study Group (1993) An international association between Helicobacter pylori infection and gastric cancer. Lancet 341: 1359–1362

    Article  Google Scholar 

  • Tigges H, Fuchs KH, Maroske J et al. (2001 ) Combination of endoscopic Argon plasma coagulation and antireflux surgery for treatment of Barrett’s esophagus. J Gastrointest Surg 5:251–259

    Article  PubMed  CAS  Google Scholar 

  • Trichopoulos D, Ourano G, Day NE et al. (1985) Diet and cancer of the stomach: a case-control study in Greece. Int J Cancer 36:291

    PubMed  CAS  Google Scholar 

  • Tsuji Nishiguro S, Mano M et al. (2000) Time trends for small gastric cancer in Japan. Gastric Cancer 3:123–127

    Article  Google Scholar 

  • Van der Veen AH, Dees J, Blankenstein JD, Van Blankenstein M (1989) Adenocarcinoma in Barrett’s oesophagus:an overrated risk. Gut 30 (1): 14–18

    Article  PubMed  Google Scholar 

  • Viste A, Bjornestad E, Opheim D et al. (1986) Risk of carcinoma following gastric operations for benign disease. Lancet II: 502

    Article  Google Scholar 

  • Wienbeck M, Berges W (1981) Oesophageal lesions in the alcoholic. Clin Gastroenterol 10:375

    PubMed  CAS  Google Scholar 

  • Williamson WA, Ellis HF, Gibb SP, Shahian DM, Aretz HT (1990) Effect of antireflux operation on Barrett’s mucosa. Ann Thorac Surg 49: 537–542

    Article  PubMed  CAS  Google Scholar 

  • Williamson WA, Ellis HF, Gibb SP et al. (1991) Barrett’s esophagus. Prevalence and incidence of adenocarcinoma. Arch Intern Med 151: 2212–2216

    Article  PubMed  CAS  Google Scholar 

  • Wynder EL, Reddy BS, McCoy GD, Weisberg JH, Williams GM (1976) Diet and gastrointestinal cancer. Gastroenterology 5:463

    CAS  Google Scholar 

  • Zhang Z, Kurtz R, Yu G et al. (1997) Adenocarcinomas of the esophagus and gastric cardia:the role of diet. Nutrition Cancer 27:298–309

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Allgemeinchirurgische Klinik Markus-Krankenhaus, Wilhelm-Epstein-Straße 2, 60431, Frankfurt/Main, Germany

    Professor Dr.med. K. -H. Fuchs

Authors
  1. Professor Dr.med. K. -H. Fuchs
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

Copyright information

© 2004 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Fuchs, K.H. (2004). Risiko, Prävention und Vorsorgeuntersuchungen. In: Management des Magen- und Ösophaguskarzinoms. Onkologie aktuell. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-18700-1_4

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-18700-1_4

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-62254-0

  • Online ISBN: 978-3-642-18700-1

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation